Starting this topic to share info about the new medication elacestrant.
Elacestrant (ORSERDU) was recently FDA approved for ER+/HER2- MBC for patients with the ESR1 mutation. Just before it was FDA approved, I was able to obtain the drug through an expanded access program (thanks to WeninWI for the info!). The expanded access program required a lot of sign-offs and steps. Hopefully, now that it has been FDA approved, elacestrant is easier to obtain.
I'm currently taking the 400 mg dose daily. I think this is actually the same as the prescribed "350 mg" dose. It is a large-ish bright blue tablet. Thus far, I've mainly had a minor altered taste in my mouth (although it seems to have lessened a bit) and possibly minor joint pain in my hands and feet. I was prepared for more significant nausea and not wanting to eat, but I've had the opposite effect. I have been eating more to try to mask the weird taste, but food tastes fine.
I'd love to hear from others who have taken or who might be starting elacestrant.