Risk of dcis
Hi hope all is doing ok. Apologies if im posting to the incorrect thread. I didnt get responses from my other discussion. Moderators please feel free to move this to a more appropriate space. So a little history, im 41, no children, menstruation started at 10, never been pregnant , never breastfed. Family history with maternal grandmother and maternal aunty being diagnosed around age 50. two yrs ago i had a fibroadenoma surgically removed. About 2 months ago i had another lumpectomy for suspicious duct that was dilated, with also a bloody nipple discharge. See path report below. My question is, with having had three biopsies and 2 lumpectomies over a 2 yr period, what are my risks? over growth of cells but usual type (epithiliosis) was found, no atypia. Is it possible other ducts could be harbouring it? i have extensive duct ectasia too. Thanks in advance. Any and all advice is welcomed.
specimen 1 shows fribotic tissue with irregular proliferation of glandular structures. in parts having a fibroadenomatoid pattern. Apocrine blebbing is seen with focal cystic change whilst other areas show dilated ducts. Some of the dilated ducts contain macrophages and red blood cells and there is patchy chronic inflammation in the stroma. Minimal epitheliosis is seen but there is no cytological atypia. Immunohistochemistry using CD10, SMA, and P63 shows an intact basal layer.
Specimen 2 shows fibrofatty breast tissue with adenosis, ductal dilatation and focal apocrine change.
No obvious cytological atypia is seen. No evidence of malignancy is seen.
Whilst there is FOCAL EPITHELIOSIS, no evidence of cytological atypia, DCIS, or malignancy is noted.
Highlighed words were underlined by the specialist breast surgeon.