BRCA2 negative and now positive
Hi I posted this in Genetic testing but thought I would post her too.
Hello, I was first diagnosed in 2015 with early stage IIb. I had genetic testing done at the time and was negative for all mutations including BRCA1 and 2. I had a recurrence in 2022 and I had the Caris test done on the tumor and again no BRCA found. Just within the last month I had a PET scan turn up some swollen lymph nodes. Upon node biopsy they found breast cancer cells which means I am now metastatic. So I was on Verzenio at the time and my oncologist ordered a Gardant test to be done because he suspected that my cancer cells had mutated if the Verzenio stopped working for me. The Gardant test results came back today with a BRCA2 mutation. My oncologist says it is not something I was born with in my "germline" it is just a cancer mutation. I was wondering if this has happened to anyone else. I am more concerned if my daugher and son, sisters, etc should now have genetic testing done. He will be starting me on Lynparza asap.
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@mvspaulding we are so sorry to hear all you are going through, and so appreciate you sharing this story, as it can also help others. It would probably be a good idea to talk about this with your genetic counselor, and your family. We're here for you!
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I made the same suggestion on your other post. No need to test others at this point.
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