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Herceptin alone or (Herceptin + Perjeta) together

Hi

I am a 54-year-old female, and I was diagnosed with HER2-positive breast cancer last April. I completed 8 cycles of TCHP (Taxotere (docetaxel), Paraplatin (carboplatin), Herceptin (trastuzumab), and Perjeta (pertuzumab)] treatment and then underwent surgery to remove the cancer along with 5 lymph nodes. I am scheduled to start radiotherapy in 2 months.

Initially, I had 5 spots on my liver, which were completely resolved with treatment. However, my doctor still considers the cancer metastatic because of the prior presence of these liver spots.

My question is regarding the maintenance phase (12–16 months): Should I take Herceptin (trastuzumab) alone, or should I take both Herceptin and Perjeta (pertuzumab) in combination?

I have received differing medical opinions and would appreciate clarification.

Comments

  • maggiehopley
    maggiehopley Member Posts: 148

    I'm not a doctor, so I can't give you medical advice, but my understanding is that Herceptin alone is only for small, stage 1 cancers. Most people in your situation seem to either be getting Herceptin + Perjeta or Kadcyla (T-DM1). I was just barely stage 2 and did Taxol, Herceptin and Perjeta before surgery and Kadcyla after.

  • darkside139
    darkside139 Member Posts: 2

    many thanks @maggiehopley

    wish u all the best