AST 107/ALT 203- talk me down please
Hi Everyone,
Talk me down. I just moved across the country 2 weeks ago and saw my new oncologist yesterday. She wanted to get her own labs even though I had them done a month ago.
My cancer diagnosis:
35 year old female
Stage 1A 40% low intensity ER, 5%PR and HER2-.
Finished 4 AC, 12 weekly tax/carbo 6/25/2024 (Full pathological response)
Finished immunotherapy Feb 2025.
Lumpectomy+ Radiation
I've been on lupron and femara. Crestor (20mg 8 years)
I have been drinking more than I should probably….
I saw the results AST 107/ALT 203 yesterday and have spiraled since, She ordered an ultrasound of the liver as STAT.
Of course- I googled it and I'm scared out of my mind.
Anyone similar experiences?
Comments
-
I’m currently dealing with a similar situation. My high liver enzymes showed up incidentally on a CMP that my endocrinologist had ordered a year prior. They ran a whole battery of liver blood tests and did an ultrasound. The doctor also stopped my lovastatin which I have been taking for over two years since it can rarely cause drug induced liver injury. It’s been five months now and the AST/ALT are slowly coming down. I have an appointment with a hepatologist in a couple of weeks.
How much I drank was the first question I was asked. I stopped drinking after my first child was born since it caused migraines. The doctor said quitting cold turkey would have been his advice otherwise. Crestor can cause DILI as can chemo, immunotherapy and Femara. OTC drugs like acetaminophen are also DILI culprits.
The liver is pretty good at healing itself but anything which happens to be toxic to your liver needs to be stopped to allow repair. You should make an appointment with a liver specialist gastroenterologist to go through the process and evaluate whether there is any permanent damage (scarring.) If the ultrasound shows fatty liver you will probably be given dietary advice to follow. Sometimes you are able to restart meds in an organized challenge process to avoid the culprit(s.) Otherwise alternate drugs for your medical problems can be found.
Mets are a less likely possibility. I’ll be having a fibroscan and possibly a biopsy to check for permanent damage since the ultrasound showed some irregularities. DILI due to the statin seems to be the cause in my case but my slow rate of improvement means it will be up to the hepatologist to figure out if I need to treat my high cholesterol another way. My MO will order a liver MRI if the hepatologist thinks it is warranted.
Finding the cause of high liver enzymes is a process but most likely it will not be cancer. I hope things work out well for you.
0
