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Letrozole vs Exemestane

siggy66
siggy66 Posts: 6
in Hormonal Therapy - Before, During, and After

has anyone switched from exemestane and noticed relief from some of the side effects of letrozole?

Comments

  • moderators
    moderators Posts: 10,431

    Hi @siggy66 ,
    Many members here have shared that switching from letrozole to exemestane can lead to some relief from side effects—especially joint pain and stiffness—though experiences do vary.

    For some, symptoms improve noticeably, while others find the side effects are similar between the two medications. Because each person responds differently, it can be a bit of trial and error.

    If side effects are impacting your quality of life, it may be worth discussing a possible switch with your care team.

    Hope others will chime in with their experiences 💛

  • siggy66
    siggy66 Posts: 6
    edited April 9

    thank you for that information. I just received the exemestane this week and plan on giving it a trial run.

  • jackaroe
    jackaroe Posts: 9

    I am considering the same switch. I have tried Anastrozole and Letrozole and had terrible side effects. After a discussion with my care team, they advised that I could be experiencing similar (awful) side effects because they are like "sister" medications, but exemestane is more like a "cousin" so the side effects may be different.

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