May 25, 2021 02:43PM moth wrote:
I would encourage you to consider this:
-there are plenty of people who don't have awful side effects but they tend to not post about that. So there's a bias in the reporting.
-your Oncotype recurrence score is assuming you will take your hormone therapy. If you take that off the table, your risk of recurrence goes up.
-the recurrence all oncologists are trying to prevent with this medicine is metastatic recurrence. That is not curable. It's fatal. I feel we're sanitizing things by saying 'recurrence risk' (which of course can also be regional - ie in the breast, but that's not the one we're worried about). Hormone therapy is trying to reduce your risk of terminal cancer which will kill you.
-you can put your stats into Predict - a well validated tool - and see how survival rates over 5/10/15 years play out with and without hormone therapy. https://breast.predict.nhs.uk/tool Think about which group you would hope to be in in 15 yeas.
-consider also that most premenopausal women are hoping to live longer than 15 years & the risk of recurrence of hormone positive breast cancer continues beyond that 15 years.
As a stage 4 pt, I'm hugely biased to say anything you can do to reduce risk of metastatic recurrence is worth it because there's no going back if it metastasizes. But everyone has different risk profiles. I am sad and mad that my cancer returned but I know I did everything I could to reduce my risk of that happening. If I hadn't I'd have huge regrets. Others feel differently and as with so much, there's evidence and then there's what you choose to do with it.
It's a lot to think about. Best wishes
Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the OddsDx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, ER+/PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External Hormonal Therapy 12/16/2020 Femara (letrozole) Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone