Topic: Scared thick uterus lining

Forum: Hormonal Therapy - Before, During, and After — This is a safe place to share your experiences of others considering or on hormonal treatment.

Posted on: Feb 24, 2022 06:17PM

Posted on: Feb 24, 2022 06:17PM

livinginparadise wrote:

Hi everyone!


Went in today for a vaginal US which shows very thick uterine lining. No polyps or fibroids.

My last two periods have been very heavy and painful and last longer than usual.

The Dr said this could be caused by the tamoxifen but that I need a biopsy.

I'm obviously scared, and sad. Just hearing the word biopsy, again. And knowing this is my life, I will always need tests and tests and tests. Will I ever stop feeling scared?


Any of you experienced thickening of the uterus with tamoxifen

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May 22, 2022 05:02AM veeder14 wrote:

Hi eauclaire

My uterine lining was 2mm when I started Tamoxifen and 17 mm 4 months later. I wasn’t taken off of Tamoxifen but had a hysterectomy so I could continue taking it. I was 61 and post menopausal at that time. I didn’t want to switch to AL medication instead.


sounds like your lining is getting thicker but no where near how quickly mine did. I just know my lining thickness was out of control. Why would you need a biopsy? Are you having bleeding? Let us know what your Oncologist recommends


Dx 1/2/2018, ILC, Left, <1cm, Stage IB, Grade 1, 0/7 nodes, ER+/PR+, HER2- Surgery 1/26/2018 Lumpectomy; Lumpectomy (Left); Lymph node removal Radiation Therapy 3/8/2018 Hormonal Therapy 2/28/2019 Hormonal Therapy
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May 22, 2022 05:49AM rah2464 wrote:

Eauclaire that is the plan with me but that means going to an AI and that gets complicated with my bones. My lining has thickened to 8.7 and I have had some bleeding. So off for a procedure for me. You should have a biopsy just to make sure - but what a pain. Your oncologist should refer you to an oncological gyno for care. In fact, I would think they would refer you without even having to see you just to get the ball rolling. That is what my oncologist office does but everyone different. Nothing about this is easy is it?

Dx 5/23/2018, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- Surgery 6/27/2018 Mastectomy; Mastectomy (Left); Mastectomy (Right); Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Hormonal Therapy 7/27/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 22, 2022 11:30PM rain88 wrote:

I was peri-menopausal before starting on Tamoxifen, and after 15 months on it, I had a massive bleeding. The vaginal US showed a 24 mm thickened uterus, but in turned out it was a large - benign PHEW! - endometrial polyp. My MO did take me off Tamoxifen though, and advised to stay off it.

Dx 27/7/2019, Mucinous, 11 mm, Stage 1, Grade 1, 0/10 nodes, ER+/PR+, HER2-, Lumpectomy (right), Radiotherapy, Tamoxifen (15 months) Surgery 10/1/2019 Surgery 10/1/2019 Radiation Therapy 11/27/2019 Whole breast: Breast Radiation Therapy 11/27/2019 Whole breast, Radiation boost: Right breast Radiation Therapy 11/27/2019 Whole breast, Radiation boost: Right breast Hormonal Therapy 1/1/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy; Lumpectomy (Right) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole breast, Radiation boost: Right breast Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy (Right)
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May 24, 2022 03:51PM ladyc2020 wrote:

livinginparadise-

I was taking Tamoxifen for less than 2 months and developed thickened lining - 18mm. Had the biopsy and hysterscopy and d/c. All benign. Stopped tamoxifen right away and did the gene test - I don’t metabolize tamoxifen so all side effects and no benefit. Fingers crossed for you.

Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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May 29, 2022 03:14PM - edited May 29, 2022 03:16PM by pinger2474

Thanks Rah for your well wishes. Since the ultrasound which uncovered 14mm lining, I ended up getting a very heavy period after not having a period in 8 months and another period the following month. So even though I'm going to be 56 this year I am clearly not going into menopause. Would having a period decrease the lining?

I did end up getting a uterine biopsy which was interesting because the gynecology oncologist couldn't see the cervical polyp that my regular gynecologist mentioned. Maybe it detached with the heavy period? They did find a benign endometrial polyp which I am planning to have removed soon. Rain, I did ask about whether I should stop my Tamoxifen usage which is only 5mg a day but both. MO and GO said no. Are you on something else? Hope you are doing well. We have the same type of BC, mucinous.

Hope everyone is staying safe and healthy.

Dx 7/1/2020, IDC: Mucinous, Left, 2cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 7/23/2020 Lymph node removal; Mastectomy Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 29, 2022 03:48PM rain88 wrote:

Pinger, I am doing all right, thanks. I am not on anything else. I was on 10mg of Tamoxifen, as I couldn't tolerate well the 20mg dose. On 10 mg, I still had lots if side effects, but tolerable. After the episode of heavy bleeding we discussed switching to an AI, but my MO pointed out that I would most likely have another plethora of side effects. He then suggested to stay off estrogen blockers all together, since the benefit from them in my case would be in the range of 1 to 3%. Our type of cancer, as you most likely know, is also less aggressive, so I took that into account when I made the decision. All the best and lots of positive vibes going forward. ♥️

Dx 27/7/2019, Mucinous, 11 mm, Stage 1, Grade 1, 0/10 nodes, ER+/PR+, HER2-, Lumpectomy (right), Radiotherapy, Tamoxifen (15 months) Surgery 10/1/2019 Surgery 10/1/2019 Radiation Therapy 11/27/2019 Whole breast: Breast Radiation Therapy 11/27/2019 Whole breast, Radiation boost: Right breast Radiation Therapy 11/27/2019 Whole breast, Radiation boost: Right breast Hormonal Therapy 1/1/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy; Lumpectomy (Right) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole breast, Radiation boost: Right breast Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy (Right)
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May 30, 2022 05:36AM rah2464 wrote:

Pinger - the heavy period should shed the uterine lining but I would plan on a follow up pelvic ultrasound since you had a clean biopsy and you are continuing on the tamoxifen. I would think your GO would have that it the plan as an annual check.

My D&C is Wednesday will be so glad to get it done and determine if I have an issue or not. My MO has already pulled me off the Tamoxifen. I will get my original tumor tested early (at four years not five) to see if I need to try an AI.

Dx 5/23/2018, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- Surgery 6/27/2018 Mastectomy; Mastectomy (Left); Mastectomy (Right); Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Hormonal Therapy 7/27/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jun 3, 2022 02:24AM ladyc2020 wrote:

rah - I hope you’re feeling well after the d/c yesterday. Fingers crossed for you.

Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Jun 3, 2022 05:01AM rah2464 wrote:

Thank you so much ladyc2020 ! My results posted late yesterday and thankfully all benign. I was anticipating some dysplasia but all clear whew! Thankful it won't be a hysterectomy summer.

It will be interesting to see where my post op discussion goes given the level of irritation in my uterus.


Dx 5/23/2018, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- Surgery 6/27/2018 Mastectomy; Mastectomy (Left); Mastectomy (Right); Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Hormonal Therapy 7/27/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jun 3, 2022 06:30AM salamandra wrote:

Yay!!

Dx at 39. 1.8cm. Oncotype 9. Dx 9/19/2018, IDC, Right, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Surgery 10/18/2018 Lumpectomy; Lymph node removal Hormonal Therapy 11/1/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 12/3/2018 Whole breast: Breast Hormonal Therapy 12/19/2019 Fareston (toremifene)

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