Posted on: May 29, 2016 08:26PM
Does anyone have information about taking DIM with Femara? I'm post menapause/post bc. Just started Femara a month ago and I'm curious if DIM would help metabolize/flush estrogen, and if that would help with the side effects. Or if there are any negative interactions that anyone knows of. My docs look at me like I have three heads when I ask about any natural/holistic support or supplements. Ugh.
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Apr 14, 2017 11:32AM - edited Apr 14, 2017 11:34AM by geohart
Apr 14, 2017 11:34AM geohart wrote:
I am wondering the same thing. I am about to start femara and really nervous about it due to osteopenia. I was thinking of taking half dose and supplementing with DIM. I can't find any information of drug interactions. My Onc is not open to Complementary therapies either.
Apr 15, 2017 08:53AM dtad wrote:
High guys. IMO there is no need to take DIM with Femara. I take DIM inlleu of anti hormone treatment to avoid the SEs. Not saying that's what everyone should do. Jus my opinion...
Apr 15, 2017 03:30PM - edited Apr 15, 2017 03:33PM by labelle
That was my first thought too, that someone taking an AI would not have any estrogen to metabolize, but AI therapies like Femara prevent only about 1/2 of expected recurrences. What about everyone else?
In women who take an AI and have a recurrence, what happens? Does the AI somehow fail to block all the estrogen production? If so, perhaps taking DIM might not be a bad idea. Because AI therapy obviously doesn't work for everyone,(although I'm not exactly sure why) and it doesn't prevent anywhere close to all expected recurrences, using DIM as a back-up might make sense. By nearly all reports taking DIM is as safe as eating lots and lots of brocolli and as far as supplements go, it is pretty affordable.
I take DIM with tamoxifen, but that is a whole different ballgame, it works (when it works) quite differently and taking DIM makes a lot of sense to me.
Apr 16, 2017 07:46AM dtad wrote:
labelle...as usual your post makes a lot of sense. You are right!
May 7, 2017 09:37PM ChiSandy wrote:
I’ve read the reason for ER+ recurrence is not that the AI inadequately reduces estrogen (AI “failure”), but that the tumor cells can evolve to synthesize their own estrogen. Also, new research (recommended by the Mods) indicates that older women (IIRC, >60) with less-aggressive tumors can safely stop AIs after 5 yrs. because our life expectancies are shorter—we’d die of other age-related natural causes before ER+ mets would get us. Although it is true that for us old farts, continuing to suppress estrogen after 5 yrs lessens the chance of mets, apparently, it doesn’t extend life.
Jul 8, 2017 01:55AM Sonya9 wrote:
Iabelle you said you take DIM with tamoxifen? I started tamoxifen 2 months ago and my oestrogen levels have tripled- so I'm looking for a natural supplement I can take with it. My onc ignores all discussion of natural treatments. Did DIM + tamoxifen work for you?
Jul 8, 2017 02:06AM Momine wrote:
The AI prevents your body from converting testosterone into estrogen. So there is no need to "flush" any estrogen. However, from stuff I read (albeit a long time ago) a high-fibre diet and probiotics can help eliminate any residual estrogen.
Jul 28, 2017 07:55AM Momine wrote:
I didn't find anything about femara, but found the following on possible interaction between Tamox and DIM:
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