Topic: All About Doxil

Forum: Stage IV/Metastatic Breast Cancer ONLY — Please respect that this forum is for members with stage IV/metastatic breast cancer ONLY. There is a separate forum for caregivers and friends: Caring for Someone with Stage IV or Mets.

Posted on: Apr 10, 2019 02:04PM

Posted on: Apr 10, 2019 02:04PM

wallaby715 wrote:

As I haven't seen a specific page related to just Doxil treatment, I thought I'd start one because that is likely my next treatment progression and I've seen little discussion of it here. So, who has been on Doxil? What were the SEs? How did it affect you after the treatment, i.e. how long were you not feeling well or completely "down"? How long have you been on it? Anything else you can think of to relate would be helpful! Thank you!

Cindy

Dx 10/19/2006, ILC, Right, 5cm, Stage IIIC, ER+, HER2- Surgery 11/3/2006 Mastectomy: Right Chemotherapy 12/6/2006 AC Radiation Therapy 6/18/2007 3DCRT: Chest wall Hormonal Therapy 9/6/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/17/2016, Right, Stage IV, metastasized to bone/liver/lungs, ER+, HER2- Surgery 3/25/2016 Targeted Therapy 3/31/2016 Ibrance (palbociclib) Hormonal Therapy 10/27/2017 Faslodex (fulvestrant) Targeted Therapy 3/21/2018 Afinitor (everolimus) Hormonal Therapy 3/21/2018 Aromasin (exemestane) Chemotherapy Taxol (paclitaxel) Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone
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May 30, 2019 02:57PM Nancylm wrote:

Hi Lucy, You are so cute , and much loved I'm sure.💖💖. My kitty , Abbey, has to have surgery. She was restless and in some pain. Vet gave her a 2 week antibiotic shot. She is fine now, but they found 2 bladder stones and the have to be removed or could be a big problem later. Cost so far $1200.

Now about the doxil. I have been in bed for 7 days. Nothing but misery. Weak and some nausea. Each treatment puts me down with major fatigue. Has any one had a chemo that wasn't this bad? Well it's back to bed and back to prayers for all of us. Nancy (bye Lucy)🐾











Dx 2/11/2011, Left, <1cm, Stage IV, metastasized to lungs, Grade 1, 0/16 nodes, mets, ER+, HER2-
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May 30, 2019 05:16PM msmann63 wrote:

Hi Nancy -

I’m so sorry you’re not feeling well. I had my 2nd Doxil treatment last Thursday. I’ve been fairly good except for the blistered and peeling feet. Today, however, I have been totally exhausted and have a return of back pain. The Doxil has been easier than other infusion chemos I’ve had (fewer digestive issues and nausea). I wish I had helpful tips for you. I can only say rest as much as possible and let your doc know the effects you’re experiencing.

I’ll be praying extra hard for all of us! 🙏🏻🙏🏻💕💕

Bridget

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May 30, 2019 06:47PM Nancylm wrote:

May you have heaven in your heart

Starlight in your soul

And Angels all around you


♥️Blessings for all. Hope everyone has a nice weekend with plenty of relaxing. Nancy

Dx 2/11/2011, Left, <1cm, Stage IV, metastasized to lungs, Grade 1, 0/16 nodes, mets, ER+, HER2-
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May 30, 2019 07:15PM msmann63 wrote:

💕💕

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May 30, 2019 07:49PM wallaby715 wrote:

Nancy, I'm so sorry to hear your kitty has to have surgery. I'm sure it will turn out OK...Lucy sends her hugs!

And I'm also sorry you are feeling so bad. I wish the treatments could be easier on you. I had 3 liters of fluid drained today so I am feeling better, although I did not feel as bad when I went in this time as the last. Tomorrow I will get my Doxil and Zometa. Good thing there is a golf tournament to watch on TV this weekend as I command the family room from my recliner!

Here's to feeling better and many prayers for all of us!

Cindy
Dx 10/19/2006, ILC, Right, 5cm, Stage IIIC, ER+, HER2- Surgery 11/3/2006 Mastectomy: Right Chemotherapy 12/6/2006 AC Radiation Therapy 6/18/2007 3DCRT: Chest wall Hormonal Therapy 9/6/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/17/2016, Right, Stage IV, metastasized to bone/liver/lungs, ER+, HER2- Surgery 3/25/2016 Targeted Therapy 3/31/2016 Ibrance (palbociclib) Hormonal Therapy 10/27/2017 Faslodex (fulvestrant) Targeted Therapy 3/21/2018 Afinitor (everolimus) Hormonal Therapy 3/21/2018 Aromasin (exemestane) Chemotherapy Taxol (paclitaxel) Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone
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May 30, 2019 07:55PM wallaby715 wrote:

Hi Bridget: Glad to hear you are doing OK even if you are fatigued. My turn comes tomorrow. Please keep us updated on how you're feeling!

All the best!

Cindy

Dx 10/19/2006, ILC, Right, 5cm, Stage IIIC, ER+, HER2- Surgery 11/3/2006 Mastectomy: Right Chemotherapy 12/6/2006 AC Radiation Therapy 6/18/2007 3DCRT: Chest wall Hormonal Therapy 9/6/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/17/2016, Right, Stage IV, metastasized to bone/liver/lungs, ER+, HER2- Surgery 3/25/2016 Targeted Therapy 3/31/2016 Ibrance (palbociclib) Hormonal Therapy 10/27/2017 Faslodex (fulvestrant) Targeted Therapy 3/21/2018 Afinitor (everolimus) Hormonal Therapy 3/21/2018 Aromasin (exemestane) Chemotherapy Taxol (paclitaxel) Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone
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Jun 1, 2019 09:49AM msmann63 wrote:

Hi Cindy! How was your treatment?

Bridget

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Jun 1, 2019 11:41AM wallaby715 wrote:

Bridget: I am somewhat surprised at how good I feel today! No need for any Zofran (anti-nausea) pills today or yesterday evening. I am waiting for the other shoe to drop, however, knowing that fatigue or nausea can hit at any time. I'm sure the paracentesis has something to do with my feeling better and having more energy, combined with being able to eat a more normal amount because of the para. Not that I'm out mowing my lawn in back! I'm not quite that ambitious and my gardners will be here shortly to do it! I will be up and down most of the day as I got a new Shark stick vacuum that I LOVE so will be vacuuming the mountains of Labrador hair wafting around my family room!

My treatment this time took forever! I got there at 10:45 a.m., had labs drawn and then about 11:20 went back to start treatment. I got home at 2:00 p.m. and it's only about 20 minutes away from my house! I get the Zometa at the same treatment so that takes about 20 minutes extra on top of the Doxil etc. The good part of that is they only had to stick me once to get the IV in!

So, so far, so good! I do have some pain in my spine which I believe is from the Zometa and I hope means it is filing in those holes that are there and attacking what cancer is still there. It's a pretty consistent reaction to the Zometa for me.

Hope you're doing well and have a great weekend!

Cindy

Dx 10/19/2006, ILC, Right, 5cm, Stage IIIC, ER+, HER2- Surgery 11/3/2006 Mastectomy: Right Chemotherapy 12/6/2006 AC Radiation Therapy 6/18/2007 3DCRT: Chest wall Hormonal Therapy 9/6/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/17/2016, Right, Stage IV, metastasized to bone/liver/lungs, ER+, HER2- Surgery 3/25/2016 Targeted Therapy 3/31/2016 Ibrance (palbociclib) Hormonal Therapy 10/27/2017 Faslodex (fulvestrant) Targeted Therapy 3/21/2018 Afinitor (everolimus) Hormonal Therapy 3/21/2018 Aromasin (exemestane) Chemotherapy Taxol (paclitaxel) Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone
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Jun 2, 2019 08:20AM msmann63 wrote:

And the mouth sores have raised their ugly heads......

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Jun 2, 2019 03:50PM wallaby715 wrote:

Bridget: So sorry to hear that! I hate those things. So far, I have had a couple from the first treatment but they went away fairly fast. I hope they don't show up from this most recent treatment. I hope they make a quick exit for you!

Cindy

Dx 10/19/2006, ILC, Right, 5cm, Stage IIIC, ER+, HER2- Surgery 11/3/2006 Mastectomy: Right Chemotherapy 12/6/2006 AC Radiation Therapy 6/18/2007 3DCRT: Chest wall Hormonal Therapy 9/6/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/17/2016, Right, Stage IV, metastasized to bone/liver/lungs, ER+, HER2- Surgery 3/25/2016 Targeted Therapy 3/31/2016 Ibrance (palbociclib) Hormonal Therapy 10/27/2017 Faslodex (fulvestrant) Targeted Therapy 3/21/2018 Afinitor (everolimus) Hormonal Therapy 3/21/2018 Aromasin (exemestane) Chemotherapy Taxol (paclitaxel) Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Radiation Therapy External: Bone

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