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Topic: ATEMPT Clinical Trial - Roll Call

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Nov 21, 2014 11:43AM - edited Feb 7, 2017 10:43AM by MaggieCat

MaggieCat wrote:

The ATEMPT clinical trial has been going on for several years.

Are you participating?

The recruiting period is over. The planned participant level of 500 has been met.

Dx 10/16/2014, IDC, 1cm, Stage IA, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Dx 10/16/2014, DCIS, <1cm, Stage 0, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Surgery 10/31/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 12/16/2014 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 3/18/2015 Whole-breast
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Feb 7, 2020 01:00PM TinyDancer5 wrote:

TTFan - Wow, that's great news that a low carb diet helped with your neuropathy.

I had my two week checkup yesterday after my Ooph and I'm healing very well, but still a bit sore. Pathology report is negative - YAY! It's amazing how well this skin glue holds the incisions closed with no stitches.

Today I had my 5 year check up with my MO and we discussed switching to an AI - Anastrozole, now that my ovaries are gone. So I will try it for 3 months and see how I do with the side effects.

I hope everyone is doing well and have a great weekend.


Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Feb 11, 2020 09:36AM TinyDancer5 wrote:

I have been searching for Sarah Tolaney's presentation of the Atempt Trial results from the SABCS19 and I found some on Twitter (of all places). I searched "Atempt Trial" and found that many Doctors who were in the audience have taken pictures of her slides, but all of them are not there. I also thought it was interesting to read what other Doctors has to say about TDM1 and the "financial toxicity".

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Feb 17, 2020 07:16AM IsabelArcher wrote:

TinyDancer, great news about the clear path report. Hope you're all healed! I had the larger panel genetic testing last week and will get results in a few weeks.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Feb 21, 2020 06:58PM TinyDancer5 wrote:

Isabel, I hope your test results are negative.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Mar 5, 2020 08:20AM IsabelArcher wrote:

Results of my larger-panel genetic testing were all negative--no weirdo genes lurking around. I declined tests of genes for which there is no possible recommended action (as in they don't even know if you need more frequent screening--they don't know the significance of the variants or mutations), but the genetics counselor didn't see any reason to test for those based on family history anyway. I can always get tested again in a few years as the field advances. My brother had prostate cancer last year (he's fine) and also had gene testing that came back negative. This is good news for our kids.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Mar 5, 2020 10:10AM TinyDancer5 wrote:

Isabel, I'm so happy to hear that your results are negative.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Mar 6, 2020 08:32AM IsabelArcher wrote:

Thanks, TinyDancer. And I hope you're fully mended from your surgery!

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Mar 6, 2020 06:35PM TinyDancer5 wrote:

Yep, I’m all healed, thanks. I started Anastrozole on 2/26 and noticed that I feel cold/chilly all the time even while sleeping too. Except for the last few nights I am starting to heat up a bit while sleeping - about the same as when on Tamoxifen. I do have this weird thing with my pinky and ring fingers on both hands. Sometimes they will lock up, get stiff, cramp and hurt. Ouch. If I rub them, then they relax again. It doesn’t happen all the time, just once in a while.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Mar 10, 2020 12:46PM IsabelArcher wrote:

Tinydancer, I had the same thing with my little finger when on that drug--trigger finger. It drove me nuts. I also had all-over joint pain. I didn't last long on the drug. My onc took me off it since I'm so weakly ER+/PR+ anyway. Hope you have better luck adjusting to it.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Mar 14, 2020 05:45PM TinyDancer5 wrote:

Wishing all of us stay safe and healthy during this Coronavirus craziness. After going to four stores today and seeing empty shelves and the empty meat counters were a bit scary. I’m not too worried about myself at 55. I’m more worried about the elderly who can’t get around as much and who need to be protected and helped. I just hope we can all get through this safely.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Mar 23, 2020 04:04PM MIPat wrote:

The last few months have been very difficult. On December 2 my husband died unexpectedly. I am dealing with probate issues which is frustrating for a variety of reasons. Eight weeks ago I had a total knee replacement and was so fortunate and blessed that for the first four weeks my brother and sisters-in-law stayed with us to help. Now I am looking at a pandemic and financial crisis with two children under 18 being strong and confident for them, yet getting so weary. Please remember me in your prayers.

Surgery 5/30/2016 Lumpectomy: Right Dx 5/31/2016, IDC, Right, 1cm, Stage IA, Grade 2, ER-/PR-, HER2+ (IHC) Surgery 6/22/2016 Lumpectomy: Right; Lymph node removal: Sentinel Dx 6/23/2016, DCIS, Right, Stage 0, 0/1 nodes Targeted Therapy 7/31/2016 Kadcyla (T-DM1, ado-trastuzumab) Targeted Therapy 1/16/2017 Herceptin (trastuzumab)
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Mar 23, 2020 04:36PM MaggieCat wrote:

MIPat - With what you've gone through, is there anything other than remembering you in my prayers I can do? If you don't mind, tell us about your children. I have 2 grandsons (19 and 16) who lost their dad to cancer last year. Just wonder if they might be helpful in some way. Maggie

Dx 10/16/2014, IDC, 1cm, Stage IA, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Dx 10/16/2014, DCIS, <1cm, Stage 0, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Surgery 10/31/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 12/16/2014 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 3/18/2015 Whole-breast
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Mar 23, 2020 06:08PM MIPat wrote:

My daughter is 17 and very stoic. She does not like to talk about her feelings, but I periodically sit and talk with her. My father died when I was 13 and I’ve told her the she needs to work through this now or when she is thirty (like I did). She resists talking to anyone but I told both of them that we would be going to grief counseling, but now that is on hold. My son is 14 and took his father’s death hard. He will talk about his feelings with me and a few trusted adults but doesn’t like to talk with others. After the breast cancer diagnosis he had a lot of anxiety about me dying. My children have a loving support system on both sides of the family.

Surgery 5/30/2016 Lumpectomy: Right Dx 5/31/2016, IDC, Right, 1cm, Stage IA, Grade 2, ER-/PR-, HER2+ (IHC) Surgery 6/22/2016 Lumpectomy: Right; Lymph node removal: Sentinel Dx 6/23/2016, DCIS, Right, Stage 0, 0/1 nodes Targeted Therapy 7/31/2016 Kadcyla (T-DM1, ado-trastuzumab) Targeted Therapy 1/16/2017 Herceptin (trastuzumab)
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Mar 24, 2020 04:37AM MaggieCat wrote:

MIPat - Good morning. I hope this day is a good one for you. Are either of them into video games? I'm thinking that might be a silly question these days! Our 19 year old is also very stoic. Ryan went through counseling which helped to some extent. He appears to make friends online easily. Our 16 year old, Jason, is charismatic - the center of whatever group of friends he is with - very much like his father. Jason won't deal with this and to be honest is benefiting from "no school" as his grades went into the dumper this semester.

Dx 10/16/2014, IDC, 1cm, Stage IA, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Dx 10/16/2014, DCIS, <1cm, Stage 0, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Surgery 10/31/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 12/16/2014 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 3/18/2015 Whole-breast
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Mar 26, 2020 06:11PM TinyDancer5 wrote:

MIPat, I am so sorry for your loss. 🙏🏻 Wishing you peace to bring comfort, courage to face the days ahead and loving memories to forever hold in your heart.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Mar 27, 2020 11:40AM IsabelArcher wrote:

MIPat, I am so sorry and will be keeping you in my thoughts. I lost my father when I was 16, and there is no doubt it changed me forever. My mother and I had to soldier on with our separate and combined griefs (my older siblings were already married and living their adult lives). But the early loss also made me resilient, and more philosophical about life. What helped me most as a teenager was meeting a girl my age who had lost her mother early on--if your kids can talk to other kids in that situation, that might help them too. Just to feel understood is comforting.

You've had more than your fair share of terrible difficulties--I hope you can find solace in the small everyday things of life. Now that we're all homebound, those small things are what we have.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Mar 30, 2020 08:13AM MIPat wrote:

Maggie, thank you. John is very much into video games. He is able to connect with his friends during this time which is helpful since he is my extrovert. He does see a therapist and also talks with me so he is working through some of his grief. I think that he would benefit by more structure with schooling since we will probably be out of school for the rest of the year. Ava will deal with her grief in her own way with support.

Tiny thank you for your good wishes and prayers. I think that during this difficult time we can all use prayers.

Isabel, loosing our fathers does cause us to be more resilient. The loss is always there. My children are resilient. They lost their biological families, their first language, and culture. There is a fear that something will happen to me when they are young I don’t want them to loose any more.

As much as I panic every year when my mammogram is due, I am freaking out more this year because my April appointment was cancelled and rescheduled for August. Trying not to worry


Surgery 5/30/2016 Lumpectomy: Right Dx 5/31/2016, IDC, Right, 1cm, Stage IA, Grade 2, ER-/PR-, HER2+ (IHC) Surgery 6/22/2016 Lumpectomy: Right; Lymph node removal: Sentinel Dx 6/23/2016, DCIS, Right, Stage 0, 0/1 nodes Targeted Therapy 7/31/2016 Kadcyla (T-DM1, ado-trastuzumab) Targeted Therapy 1/16/2017 Herceptin (trastuzumab)
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Apr 2, 2020 10:34AM IsabelArcher wrote:

MIPat, just checking in to say hello, and send good wishes to you and your kids. The mammo delay adds worry but I don't think it add any actual risk. I remember my oncologist comforting me that things really don't move quickly with BC (I had a few months delay between diagnosis and surgery), and that was back when we all actually had it (so even less of a thing for routine testing). All best to you.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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May 20, 2020 01:33PM MIPat wrote:

I was able to get in today for my mammogram and got a clean bill of health! I was nervous (ok, cry high anxiety level) because I have been having some issues with the left side but it reminded me of when I was younger and had more problems with cystic breasts. Neither the mammogram or ultrasound showed anything. So I am happy.

Surgery 5/30/2016 Lumpectomy: Right Dx 5/31/2016, IDC, Right, 1cm, Stage IA, Grade 2, ER-/PR-, HER2+ (IHC) Surgery 6/22/2016 Lumpectomy: Right; Lymph node removal: Sentinel Dx 6/23/2016, DCIS, Right, Stage 0, 0/1 nodes Targeted Therapy 7/31/2016 Kadcyla (T-DM1, ado-trastuzumab) Targeted Therapy 1/16/2017 Herceptin (trastuzumab)
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May 25, 2020 01:28PM IsabelArcher wrote:

MIPat--this is wonderful to hear! Great news!

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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May 26, 2020 02:29PM TTfan wrote:

Congrats MIPat!

How is everybody doing in these Covid times? I'm feeling lucky to be retired. No extra risk as I would have had working at the hospital and no financial impact other than the stock market hit, but we'll weather that. My main complaint is missing being with my grandkids. One son's family is at pretty high risk for a variety of reasons, so we've not seen them since February. The other one is being super careful, both of them working from home and no exposures other than careful grocery shopping, so we decided to risk a visit for mother's day. Heaven on earth is holding your grandbaby again! She's almost 2 and before the stay at home order we were babysitting for her twice a week, so totally in each other's lives. I miss her soooo bad! Her 2nd birthday is coming up, so we may do another (very careful) cheat day with us and her other grandparents.

Hope you all are well and coping with these trying times!

Dx 9/21/2014, IDC, <1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ Surgery 10/9/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 12/2/2014 Herceptin (trastuzumab) Chemotherapy 12/2/2014 Taxol (paclitaxel) Radiation Therapy 3/23/2015 Whole-breast: Breast Hormonal Therapy 4/27/2015 Arimidex (anastrozole) Hormonal Therapy 3/1/2016 Aromasin (exemestane) Hormonal Therapy 8/7/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jun 17, 2020 08:48AM IsabelArcher wrote:

Hello, TTFan! I hope by now you've had many more chances to see your grandchildren! As for these Covid times, I'm lucky that I have always worked at home, so for me that part of life went on pretty much as before. What grieves me is the loss of arts events this summer and into the fall. My older son is getting married next summer (in our backyard), so I really really really hope large gatherings will be OK by then! Best wishes to all.

Dx 5/2013, IDC, <1cm, Stage IB, Grade 3, 0/0 nodes, ER+/PR+, HER2+ Surgery 7/8/2013 Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy 9/4/2013 Kadcyla (T-DM1, ado-trastuzumab)
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Nov 26, 2020 06:47PM TinyDancer5 wrote:

Wishing everyone here a Happy Thanksgiving!🦃🍁 I hope you all are well and staying safe during the holidays and end to this crazy year.

Diagnosed at age 51. Dx 5/28/2015, IDC, Left, 1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/22/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 8/20/2015 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 11/10/2015 Whole-breast: Breast Hormonal Therapy 1/19/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 8/26/2016 Surgery 1/24/2020 Prophylactic ovary removal Hormonal Therapy 2/26/2020 Arimidex (anastrozole)
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Jan 9, 2021 09:39AM littlecheese wrote:

I was diagnosed right when COVID hit so my oncologist was able to get me approved for Kadcyla to minimize visits to the treatment center. Encouraged by all of your comments that participated in this trial. Have a few more treatments to go and hoping I have the same good results.

Dx 3/2020, IDC, Left, 1cm, Stage IA, Grade 3, 0/7 nodes, ER+/PR+, HER2+ (IHC) Targeted Therapy Kadcyla (T-DM1, ado-trastuzumab) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Mastectomy: Left; Prophylactic mastectomy: Right Surgery Lumpectomy: Left; Lymph node removal: Sentinel
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Jan 9, 2021 02:30PM MaggieCat wrote:

Thanks for your message Little Cheese! Our small group - here on BC.org - had great results. I queried my oncologist in November about the other participants from our location. All are doing great, no cancer return - 5+ years out. Maggie

Dx 10/16/2014, IDC, 1cm, Stage IA, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Dx 10/16/2014, DCIS, <1cm, Stage 0, Grade 3, 0/6 nodes, ER-/PR-, HER2+ Surgery 10/31/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 12/16/2014 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 3/18/2015 Whole-breast

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