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@hoping4hope, I have posted two replies and lost them both - lol - technology wins. I am on Ribociclib/letrozole. So far, they have been effective. You will find great support and experience on this website. I know how difficult it can be but the best advice I can give is to be kind to yourself. This can be a long enough road, without being hard on yourself. Take each day as it comes. In your pocket💓