Best Of
Re: Are you currently (or have you been) in a Clinical Trial?
Well, here is something exciting, just published in Nature Communications:
This is preclinical (studies in mice)- researchers treated TNBC with radiation and immunotherapy (anti-CTLA4) and saw T cells enter the tumors, but nothing much else happened to shrink the tumors. They then added on Keytruda, which didn't help. they then added a CD40 agonist antibody- these antibodies stimulate dendritic cells, which are the first step in the killing of cancer cells- these are cells that eat the tumor cells and extrude cancer proteins on their surface to activate and target nearby T cells. the results were dramatic and most of the tumors went away.The three-pronged therapy resulted in complete or almost complete elimination of targeted tumors, as well as partial control of tumors that were not targeted by the radiation. However, the approach was not effective in eliminating micrometastases that had spread to the lungs. So not a cure but maybe a big step forward to make immunotherapy work in TNBC. A clinical trial is planned for MBC as the next step forward.
Re: My Husband, My Life, My Love, My Family, My Cancer
Well, Tigger is liking the kitten food which is good, really am trying to fatten him up a bit since he is thinner than he used to be. Ava is still getting regular food since she would just puff out like a marshmallow on kitten food.
Re: My Husband, My Life, My Love, My Family, My Cancer
Thank you everyone, I appreciate all the happy congrats 😁
illimae
Re: My Husband, My Life, My Love, My Family, My Cancer
Yes, I do enjoy the ride through looking at the lights as well.
OMG, there is a lot being built where the wee grocery store was built, there will be a Wendy's, already have a Tim Hortons and there will be a Dollar Tree going in. Our dollar Trees do not have freezer sections, good storage though. Once the snow is gone, can take Paratransit and look around. It is milding up next week though so snow will definitely do some good melting as well. A discount store may be going in as well. Interesting, I like where I am located as there are many places to go grocery shopping within a couple of square kms or a square mile.
Re: Can we have a forum for "older" people with bc?
Morning in central Illinois today is cloudy. We are due for more rain, but not sure when. That is REALLY making me appreciate Cindy's pictures and thank you so much. The water looks so nice as well. I'm a pushover for that as well.
My cousin did hypnosis to quit smoking and she seemed to have done fine with it after many yrs. of her habit. I'm told that a lot of people try several times before they get it done. I sure did. I recall one time when a friend and I bought a sm. pack of four filters. Each one used two weeks at a time removed more nicotine. I got all the way through the filters, and they worked really well. About three wks. later I discovered that I didn't have any cigarettes and promptly went out and bought some.
So much for having been a quitter for three weeks. It was a long time before I tried again, and I even tried the four filters again. Didn't work for me that time. What finally worked was just wanting to bad enough to figure out the best way and by that time I knew the "craving" would get me and that was what I most needed to defeat.
Interesting about the dreams. I don't remember dreams much so I don't recall if I had any. I think I dream more now because I think some of mine are caused by medication I take. My last remembered' dream was of giving Dh left-over food for supper that had been accidentally left out overnight. I didn't eat any but gave it to him and acted just like it had been stored properly the night before. He seems to still be alive, so it was just a dream.
Carole, the weight loss didn't take long after all. Good for you.
Chris, that was interesting to hear that we had highly recognized addictions so long ago — in BC era. Also I guess that it was gold as well.
I hope you will all have a wonderful day. I'm going to go look at Cindy's sun again.
Re: For Arimidex (Anastrozole) users, new, past, and ongoing
I am one of those who chose quality of life over hormone blockers. I am 71 and had surgery for stage 1 grade 1 breast cancer, no lymph node involvement. I did a lot of homework before making my decision. I studied the drug’s effects on the body and read hundreds of patient experiences. It seems the AIs speed up the aging process and it’s already going fast enough for me. I already have joint pain, trouble sleeping and am losing bone. I don’t need any of these to intensify. Many people report feeling like 90 on these drugs. I’m living my healthiest life possible and realize I’m taking my chances, but it’s a quality of life issue for me. Maybe 7 years on the drug is enough for you. Something to discuss with your doctor. We are all different and what is good for one may not be good for another. Btw, I took Fosemax years ago and was only on it for 15 months. I had horrific joint, muscle and connective tissue pain. I quit bone drugs too. I do my best to exercise to keep my muscles strong and flexible. It’s the best I can do.
saleen19
Re: Bone Mets Thread
Hello,
Just wanted to give you a quick update… I saw my oncologist on Wednesday and he didn’t seem to be too concerned about my cancer marker jump, he said he doesn’t find this particular test reliable therefore doesn’t like to do it all the time. He did move my scans to Jan 8th just to make sure all is good, so hoping for the good news 🙏🙏🙏 as I’ve been mainly stable since started the treatment in February ( ribociclib, falsodex, zometa / switched to xgeva last month)
I will try not to stress about this now over holidays and hope for the good news in the new year!
vik2ri
Re: Can we have a forum for "older" people with bc?
Yes, there is plenty in the OT about that. "Hunger for gold is made greater as more gold is acquired." Aurelius Prudentius Clemens AD 348-413 was a Christian, and I am sure he used scripture to firm up that perception. Yes, Jackie, you can use that one down the road, and I will make no comment. LOL!
mcbaker
Re: My Husband, My Life, My Love, My Family, My Cancer
Mara - Out to see the Christmas lights - good for you. That is always so nice. A friend of mine told me that she and another one of her friends tried to do that here the other night, but the weather was just too nasty, so they were half way to a neighborhood known for light displays and turned around and went back. Thought they might try it later. I just enjoy whatever I can see of my neighbors' from my apartment window anymore. It's not as good as getting out, but it does make the holiday a little brighter.