Best Of

Maggie, thank you so much for the info you shared. It’s valuable, knowledge is power, especially when the healthcare team sometimes misdiagnoses us. I’ll dig into those symptoms since I have some of them.

Dulcea, thank you for opening this discussion. we learn so much from each other here, information we rarely get from our care teams.

Threetree, have you decided what treatment you prefer for your liver mets?

@maggie15 thank you so much! I have actually considered that it was the Enhertu increasing the issues with my liver and the ascites, especially since the first time I had the ascites, was a week after my first infusion. The increase in my liver numbers were thought to be a combination of both the Enhertu and the cancer. With your information though, I can do more digging and ask more questions along that vein. And now that you mention a statin, someone at the hospital had mentioned that to me. I think we all just assume that since I have cancer in my liver, it must be due to that.

Thank you again so much!

@dulcea, Have you been checked for drug induced liver injury? It’s rare but I ended up with sudden cirrhosis not related to cancer or anything else caused by a statin. There is a long list of drugs that can cause DILI and Enhertu is one of them. It puzzled four other specialists for eight months before it was diagnosed by a gastroenterology fellow specializing in hepatology who monitors my Barrett’s esophagus. Stopping the offending drug and taking steroids has helped. Your problem could be something else but it wouldn’t hurt to ask. Good luck finding the cause.

Hi Candy. Yeah, I need to fill out my profile. Yes, I’m bone only. My CT results just came in- all stable. Now I can exhale. My MO is fine doing it only once a year, but always gives me the option to scan pretty much whenever I want. I usually do every 6 months. I’m still on Ibrance and Femara and have been since 2017.

The crazy thing is, when I was very first diagnosed stage 2A, Ibrance was still in clinical trials and would not have been available. When I was dx stage iv in 2017, I started on it right after having a spinal fusion. They found a tumor wrapping itself around my spinal column. My neurosurgeon told me that if we had waited only a week to operate, I would be in a wheelchair now. It had wrapped itself around so tightly that it would have taken my ability to walk. I’m grateful every single day that I can get up and go about my normal day on my own two feet. Pretty scary when I sat and thought about it.