Best Of
Re: I say YES. YOU say NO....Numero Tre! Enjoy!
risinggoddess, welcome if you are supportive of anti-trump politics. If you are MAGA, this is not a forum for you. Not trying to be unwelcoming, but trying not to cause ill-feelings. Thank you.
betrayal
Re: I say YES. YOU say NO....Numero Tre! Enjoy!
Boy is he ever missed. Seems they had a rally in my town, too. Sorry I missed it.
One Maga on nextdoor made a comment about someone shooting at participants. Others called us traitors. I think those who have DJT syndrome are his followers. As a detractor, I do not feel I am deranged; just the opposite. I feel absolutely sane.
betrayal
Re: Stage IV MBC Fitness
I’m glad we’re all trying to keep up with the exercise. I’m still hitting the exercise classes.
aj
Re: Stage IV MBC Fitness
@threetree When you have time could you please post a picture of your footstool? I have very short legs and could use better support when I'm at the computer. Glad that your feet feel better.
Re: Can we have a forum for "older" people with bc?
Cindy - keeping your SO in my thoughts for a good outcome on the colonoscopy
Taco - enjoy golfing.
harley07
Re: Can we have a forum for "older" people with bc?
Cindy - interesting pictures. Our botanical garden and zoo all do special Christmas lights but like you, I've been there, done that.
Golf course opened this week but will be extra walking for a few weeks. I've really been lazy since it's been closed so it could be a very interesting morning. Weather is perfect however so I will give it a try. Mutz goes to the vet in the afternoon. Always a challenge although we have a wonderful, gentle vet.
This week's question for the Storybook is about our mothers - Ken's Mom and I were definitely on different wave lengths so I will really have to think about this. Sadly, DD wasn't close to either of her grandmothers. I blame them. They definitely showed preference for their biological grandchildren over their adopted ones.
Ken's watching the series. He's with you, CanaryCat.
1946taco
Re: My Husband, My Life, My Love, My Family, My Cancer
@irishlove You are right about DB and SIL, they will help. I'm giving space since SIL has something she is dealing with. She'll tell me later when I see her.
Re: My Husband, My Life, My Love, My Family, My Cancer
Good early morning all you night owls. Reading the posts to catch up it appears we need a good prayer group and lots of pockets filled with support. @shanagirl Glad to hear from you. I'm concerned about that unresolved pneumonia as it's a worry for me, too. I'm so sorry you couldn't go say those babies. I think snuggling with the wee ones is just what the doctor ordered. Please get back to being able to travel and enjoy your family.
@mara51506 Hi sweet gal. You're always organized and figuring out your plan of attack. I just know the procedure will be a success, as it was in the past. So happy that folks still know how to comfort even strangers as we are all in this together. I believe your SIL and DB will come shining thru for you. @chicagoan That is amazing how quickly you are healing and enjoying your walking. I see you said you restarted Ibrance. How long were you off Ibrance?? I'm a bit nervous since I've been off since Oct.6 and nurse said i need to stay off till I see MO on Nov. 10th. @eleanora Diverticulitis is a difficult SE to deal with. Been thru it 3 to 4 times while on Ibrance. Now the pneumonia, which is another SE is taking it's toll. I hope they sort this out and get you off antibiotics. @mkestrel I love your beautiful photography. It makes me smile. In your pockets and hoping the new plan will take good care of you for the future.
I apologize for missing so many that are struggling right now. We need stable time and I'm not talking about horses. Although I loved to ride in my younger days. Ok, I rattled on too long, but in every pocket with Halloween candy and lots of love.
Irishlove
Re: My Husband, My Life, My Love, My Family, My Cancer
@eleanora In your pocket, fingers crossed on Thursday.
@mkestrel What a beautiful serene picture, I can only imagine how nice the hot springs were. Glad you're able to breathe a little sigh of relief. May your plan be successful, fingers crossed for PET
@mara51506 Well glad you were able to test using the walker and get home safely. With your determination I know you will find the best safe method to get around. I always loved Honey-Nut Cheerios, haven't had it in years.Seems like it would be a good combo but maybe more of a snack.
@shanagirl Ugh that darn cough!! I'm sorry to hear you have to postpone your trip, cancer stinks! I like your Ortho/Onc's positive thinking we all wish the same for you.
@chicagoan Wow so happy you're making great progress!
@irishlove Oh Irish I'm sure you are exhausted! Anyone would be tired after all you have been going through. Wishing for better days soon, sending hugs and healing.
Hi to all you lovely ladies here, wishing you all a good week . Hope all appt and treatments go smoothly this week
cookie54
Re: Are you currently (or have you been) in a Clinical Trial?
Hi Saulius!! I wondered the same, and saw a couple of papers on PubMed that were one-off reports of patients who got the vaccine and had a great response to one drug or another. It's certainly possible to get a "boost" (pun intended) from a vaccine, but do remember they are talking about actual vaccine doses, which are higher than booster shots, and in one report the big benefit came after the second dose, and basically a strong reaction to the vaccine seems to correlate with general immune system mobilization. So it works on its own to give a systemic boost of immune activity, and if the cancer is already somewhat responsive to immune infiltration, etc, it boosts the effect of the treatment. But the real synergy is happening when immunotherapy is added- in part its because the immune system is increasing PDL1, thereby making the cancer more sensitive to Keytruda or other checkpoint inhibitors that work by blocking PDL1..
I really like the video in the link below, from the group at U-FLA who made this finding, they basically are working on cancer-specific vaccines and noticed that what was supposed to just be the control in their experiments (ie, an mRNA vaccine, Covid or just mRNA, not designed to target the cancer in any way) worked just as well as their anti-cancer vaccine, so it was just mRNA can boost the immune system…
There are other things this year that have popped up where drugs designed for other purposes can also stimulate immunotherapy, esp PCSK9 inhibitors (used for cholesterol) and SSRIs (anti-depressants) and so you wonder what would happen if you first got the full Covid vaccine, added immunotherapy, then the next month added PCSK9 inhibitor then another month later the SSRI, would they all work together? If you were strategic to only add one thing at a time and then check TMs to see if that one thing helped or not, that would be one way to check… Anyway, that's what I wonder, is it a case of the more the merrier? or could one of those things get in the way of how the others are acting? but, anyway, wow that all these things are available from your doctor right now, and we learned about all of them just recently…
Here is the video the lab put out:
