Best Of

@threetree and @norah2024 - I had seen a long, detailed video about it and found this short one. I just received my order and noted that it is packed in plastic. I will try half a tablet to try today because I am very sensitive:

https://www.youtube.com/watch?v=g2-0RMcygqk

@threetree , My MO always gives me a prescription for side effects meds and recommends to fill it in before starting treatment “just in case”. When I started Xeloda, she prescribed anti nausea, anti diarrhea and even an antibiotic. I use anti nausea med few times, esp in the first few months of treatment. It does not bother me much now. I started to experience more digestive issues lately but so far they could be managed with diet (i now include probiotic foods, like daily natural yogurt or skyr and I add fermented foods (kimchi, sauerkraut) as a small side dish couple of times a week. I have days when I am fatigued and need a nap, but then I have good days too, so I just take it as it comes.

My starting dose of Xeloda was 2000 mg/ day, two weeks on one week off. I had a really bad progression in my liver in February 2025 and my live panel values were so out of whack that my MO was afraid to put me on a higher dose. After a month values started stabilizing and my MO and I decided to take the risk and to increase the dose to 2500 mg/day. This is still only 60% of what would be my full dose, but it worked wonders: CA15-3 plummeted and PET scan in June confirmed a remarkable decrease in liver mets, To bring my hand food syndrome under control, we changed to 1 week on / one week off protocol, same dose, as of July 2025. I achieved NEAD by September ( 6 months of treatment).

Interestingly, at the December check up, my MO suggested to reduce the dose. I did not dare to and she kept me on 2500mg/day for now, but she also reassured me that “if it works, it works, even at a lower dose”.

Wishing you good luck, quick response and mild (or no) side effects.

@denny123 : Fantastic results! I'm so happy for you. Just a little more patience for the vegetable garden.

@bigred62 : Congratulations on your results. Yes, I confirm, taking Xeloda for one week followed by a one-week break is much easier to tolerate. I started at 3600 mg per day for 2 weeks of treatment and I was very tired. On this forum I learned a lot about the possibility of switching to a 1/1 alternation without loss of efficiency. I spoke with my oncologist and we we reduced it to 3000mg/day and 1/1. I have been taking it for over a year, my scan results are very good, no progression of the disease and markers are decreasing. I wish you much success with this treatment..

Hello and Happy New Year ! I'm just checking in to say hello and ask if anyone has had any good results from hydrogen water? I keep reading so much about it and willing to try! Google AI summarizes much of what I have read:

Hydrogen water shows promise in animal studies for preventing bone loss by reducing oxidative stress and inflammation, potentially protecting against bone issues related to estrogen withdrawal or diabetes, and even showing anti-tumor effects in some cancer models, suggesting a role in managing bone conditions like osteoporosis and potentially supporting bone health during cancer treatment, though human research is limited. It acts as an antioxidant, reducing damaging reactive oxygen species (ROS) and inflammatory cytokines (IL-6, TNF-α) that harm bone.

How it Might Help Bone Health

• Reduces Oxidative Stress: Cancer and its treatments generate oxidative stress, which damages bone cells. Hydrogen water neutralizes these harmful molecules (ROS).
• Anti-inflammatory Properties: It suppresses pro-inflammatory signals (like IL-6 and TNF-α) that drive bone breakdown.
• Protects Bone Structure: In animal models, it prevented loss of bone mineral density and improved bone strength.
• Inhibits Osteoclast Activity: It can specifically reduce the activity of osteoclasts, the cells that break down bone. 

Relevance to Cancer & Bone Metastases

• General Anti-Cancer Effects: Hydrogen has shown anti-tumor effects, potentially slowing cancer progression and reducing side effects of chemotherapy.
• Support During Chemotherapy: It can mitigate chemotherapy side effects, improving liver function and reducing inflammation, which indirectly benefits overall health during cancer treatment.
• Bone Metastases (Early Research): While direct research on hydrogen water and established bone metastases (cancer spread to bone) is scarce, its effects on bone loss (osteopenia/osteoporosis) and cancer suggest it could be a supportive therapy, though this needs more study. 

Current Status

• Promising, but Early: Much evidence comes from animal studies, but results are encouraging for bone conditions and cancer side effects.
• Needs Human Trials: More extensive clinical trials in humans are needed to confirm benefits for bone metastases and establish clear protocols, notes this Frontiers article. 

In Summary: Hydrogen water shows potential as a complementary therapy by reducing inflammation and oxidative stress, which are key factors in bone loss and cancer progression, making it an interesting area for future research in managing bone metastases. 

I was mostly interested in trying for digestive reasons and my research brought up so much more. Just curious about others' experiences?!! Thanks and have a great day. Terry B.