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BC mets in an.models reduced by mdifyng tumor electrical prop.
https://www.sciencedaily.com/releases/2022/01/2201... In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens. Marked by a breakdown in the normal electrical patterns generated by the cells, they lose their specialized functions, start expanding into a…
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liquid biopsy for early monitoring and outcome prediction
Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer https://www.nature.com/articles/s41523-021-00319-4...
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Podcast: Top Research Presented at the 2021 SABCS
Top Research Presented at the 2021 San Antonio Breast Cancer Symposium December 21, 2021 Dr. Sara Tolaney is chief of the Division of Breast Oncology and associate director of the Susan F. Smith Center for Women's Cancers at the Dana-Farber Cancer Institute, as well as associate professor of medicine at Harvard Medical…
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Podcast: Breast Cancer Research at ESMO 2021
Breast Cancer Research at ESMO 2021 October 21, 2021 Dr. Brian Wojciechowski practices medical oncology in Delaware County, Pennsylvania at Riddle, Taylor, and Crozer hospitals and also serves as Breastcancer.org's medical adviser. A native of South Philadelphia, he trained at Temple University School of Medicine and…
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Racial, Ethnic Minorities Underrepresented in Cancer Research
Racial, Ethnic Minorities Underrepresented in Cancer Research November 12, 2021 Black, Hispanic, American Indian, and Alaskan Native people are vastly underrepresented in research studies on breast, prostate, lung, and colorectal cancer. Read more...
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Cokie Roberts RIP
Stupid cancer. She was dx in 2002 at age 58 with breast cancer. RIP. 75 years old.
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Special Report: Increasing Racial Diversity in Clinical Trials
Clinical trials are the main way scientists develop new and improved cancer treatments. Yet less than 5 percent of adults with cancer participate in clinical trials, and most who do are white. Disparities in clinical trial participation among Black women could be one of the reasons they have worse breast cancer outcomes…
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BCO Revamped Section on Clinical Trials
Clinical trials are carefully designed research studies that depend on human volunteers to improve medical care over time. In cancer research, pre-clinical studies first test new treatments that show promise in the lab or in animals. These treatments may ultimately be tested in clinical trials involving people. Clinical…
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Podcast: The Importance of Diversity in BC Clinical Trials
The Importance of Diversity in Breast Cancer Clinical Trials September 15, 2021 Dr. Lola Fayanju is the Helen O. Dickens Presidential Associate Professor at the Perelman School of Medicine at the University of Pennsylvania, where she is also chief of breast surgery at Penn Medicine, as well as surgical director of the Rena…
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Enhertu shows Kadcyla Who’s Boss in HER2+ MBC / DESTINY 03
“Enhertu slashed the risk of disease progression or death by a massive 71.6% over Kadcyla in second-line HER2-positive metastatic breast cancer patients previously treated with Roche's Herceptin and chemo, AstraZeneca and Daiichi reported at the European Society for Medical Oncology 2021 virtual meeting. “The showing is so…
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Improved survival with Surgery in Metastatic Breast Cancer
Improved Survival With Surgery in Metastatic Breast Cancer | MedPage Today "Selected patients with metastatic breast cancer at diagnosis had significantly better survival with surgery in addition to systemic therapy, an analysis of almost 13,000 patients showed." "Primary Source Annals of Surgical Oncology Source…
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HER2+ update from OncLive
A recent email from OncLive.com highlights studies and treatments for HER2+ breast cancer, both early and MBC OncLive.com HER2+ Newsletter
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Seeking a unique treatment for lobular breast cancer
https://www.sciencedaily.com/releases/2021/07/2107... Though the two main histological types of breast cancer -- lobular and ductal -- are treated with the same hormonal therapies, women with lobular breast cancer often have recurrence or metastasis of the disease several years after their initial treatment. In an attempt…
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Podcast: Breast Cancer Research at the 2021 ASCO Annual Meeting
Breast Cancer Research at the 2021 ASCO Annual Meeting June 28, 2021 Dr. Jennifer Litton is a board-certified medical oncologist and professor of breast medical oncology at the University of Texas MD Anderson Cancer Center in Houston, where she is also vice president of clinical research. The 2021 American Society of…
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revolutionizing cancer therapy
https://www.sciencedaily.com/releases/2021/06/2106... Tel Aviv University's groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions. In the framework of this study, the researchers were able to create a new method of transporting RNA-based drugs to a…
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surfaces of silicone breast implants affect the immune system
https://www.sciencedaily.com/releases/2021/06/2106... Every year, about 400,000 people receive silicone breast implants in the United States. According to data from the U.S. Food and Drug Administration, a majority of those implants needs to be replaced within 10 years due to the buildup of scar tissue and other…
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New findings- improved therapy early-stage, BRCA mut.-assoc. BC
https://www.sciencedaily.com/releases/2021/06/2106... Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a drug that blocks cancer cells from repairing…
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High Dose Trastuzumab + Pertuzumab for HER2+ Brain Mets
“In the phase II PATRICIA trial reported in the Journal of Clinical Oncology, Nancy U. Lin, MD, and colleagues found that pertuzumab plus high-dose trastuzumab produced central nervous system (CNS) objective responses and clinical benefit in 68% of patients with HER2-positive metastatic breast cancer with progressive brain…
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Preprint: possible target to overcome Herceptin resistance
Sortilin-related receptor is a druggable therapeutic target in breast cancer “....Identifying alternative HER2-related therapeutic targets could offer means to overcome .... resistance mechanisms. We have previously demonstrated that an endosomal sorting protein, sortilin-related receptor (SorLA), regulates the traffic and…
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New study: Vaccine for Triple Negative BC
Has anyone heard of this new vaccine, developed by Cleveland Clinic, for triple-negative breast cancer? Key Takeaways * The FDA has approved a triple-negative breast cancer vaccine for use in human clinical trials. * The vaccine was developed by researchers at the Cleveland Clinic in Ohio and works by training the immune…
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Imaging IDs BC patients unlikely to benefit from hormone therapy
https://www.sciencedaily.com/releases/2021/02/2102... Hormone therapy commonly is given as a targeted treatment for women whose cancer cells carry receptors for estrogen. But the therapy only works for about half of all patients. Until now, there hasn't been a good way to reliably predict who will benefit and who will not.…
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NEW BCO Content: Understanding Breast Cancer Research
Check out our NEW content on how to understand breast cancer research! Understanding breast cancer research can be hard for someone who isn't a scientist. The language in research papers is very technical and complex. The point of the research may not seem clear at first glance. And you may be left wondering if the study…
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TORADOL (ketorolac) linked to Recurrence Prevention
My mantra for medical and nursing information for decades has been " Just when you think you know something look again" I thought I was done searching for an answer yesterday on something else, then I listened, "You don't know enough, look again, you don't know enough look again". That pesky little irritating voice that…
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low dose aspirin may act like an aromatase inhibitor
http://www.cnn.com/2017/05/01/health/breast-cancer...
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Mirena IUD/breast cancer
I wanted to reach out and see if anyone else had Mirena when diagnosed with breast cancer? I was only 30 years old when diagnosed and had Mirena put in about 1 year prior to me discovering a lump. I really think there may be a connection. I may be interested in getting together a class action suit, if there are enough of…
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Hormone Therapy with/without Afinitor (everolimus) SWOG-S1207
I started this clinical trial in May 2014 and would like to connect with anyone else who is on it. It's a Phase III trial for high risk hormone-positive, HER2- patients to see if adding one year of everolimus to hormone therapy improves disease-free survival. Anyone?