ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, NBN, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53, mismatch repair genes (MLH1, MSH2, MSH6, PMS2, EPCAM), and VUS (variants of unknown significance)
Anyone with stage 1, grade 1 HR+, HER2- Invasive Ductal Carcinoma with a pathogenic BLM variant? Still waiting for final pathology after lumpectomy. With this genetic variant, a history of eczema & atopic dermatitis and numerous allergies, sensitive skin and hypermobility (connective tissue disorder), I am leaning towards…
Genetic Testing Saved My Life May 31, 2024 Dr. Brooklyn Olumba explains how discovering she had a BRCA2 mutation led to earlier breast cancer screening and detection. At the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, Dr. Brooklyn Olumba was part of ASCO Voices, a program that gives people in the…
Genetic Mutations More Likely in Breast Cancer Found Between Mammograms May 15, 2024 Having a family history of breast cancer and a mutation in any of the five main breast cancer genes may increase the chance that you may discover breast cancer between your routine mammograms. Read more…
Lynparza Approved To Treat High-Risk, Early-Stage, HER2-Negative Breast Cancer With BRCA Mutation Mar 13, 2022 The FDA approved Lynparza to treat early-stage, HER2-negative breast cancer with a BRCA1 or BRCA2 mutation and a high risk of recurrence, which also has been previously treated with chemotherapy — either before or…
ASCO and SSO Update Genetic Testing Guidelines for People With Breast Cancer Apr 8, 2024 Updated guidelines say anyone age 65 or younger diagnosed with breast cancer should have genetic testing for BRCA1 and BRCA2 mutations. Read more…
Hello, I was diagnosed with breast cancer at age 29. Genetic testing was brought up shortly after my diagnosis. I decided against it, at the time, for several reasons...the cancer institute in the city I live does not have a genetic counselor so I would have had to travel 5+ hours for this, no family history of breast…
Hi, I’m in NZ - stage 4 lobular snd looking at the tests that tell you what chemo will work. I’ve done Foundation One which my oncologist recommended. I’ve just found out about the Geonostics Exacta Test - snd the Gradient test I’m confused so just wondering if anyone knows what the differences are - or which one is best.…
Anyone else get tested for PALB2 gene mutation?
Preventive Removal of Ovaries, Fallopian Tubes Linked to Better Survival in BRCA-Positive Breast Cancer Oct 25, 2023 Removing the healthy ovaries and fallopian tubes improved survival in women with a BRCA mutation who were diagnosed with breast cancer. Read more…
Dear Members, Would you be willing to share your story about genetic testing? (no pressure, only if you are inspired!) We are interested in the following questions: What led you to doing the testing? What were your results, and what choices have you made based on the findings? Was payment an issue? How have you discussed…
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