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Hormonal Treatment for Stage IV
This thread will be for the discussion of hormonal treatments as they relate to Stage IV members.
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Tried 5 drugs in the lat year, none worked
Hi all, My mother was first diagnosed with breast cancer in Nov 2014 (Grade II, ER+/PR+/HER2-). She did Chemotherapy (Doxorubicin + Cyclophosphamide + Paclitaxel) followed by radiation Then years later she found a lump on her left breast Dec 2019 and had surgery to remove it, after which the Dr said she was stage 1 because…
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FGFR1 amplification
I am asking for collective wisdom for those that have this genetic mutation. FGFR1 amplification is reported to be in 10-27% in breast cancer (per FoundationOne). I progressed after 3+ great years on Ibrance/Letrozole. Recent liver biopsy report from Foundation One(F1) showed FGFR1 amplification and ATM inversion exon 55.…
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Need Your Tips for Members Newly Diagnosed Stage IV
Looking for your tips to share with members who have been newly diagnosed stage IV/metastatic. Being diagnosed with Stage IV/Metastatic disease involves a unique set of concerns. If you could give your newly-diagnosed-with-mets self advice/tips/encouragement, what would you say? Please post in the thread below. We're…
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Stage 4 TNBC NED or Remission
Greetings everyone, I just wanted to know if there are any long term members who are NED or in Remission with TNBC. I was originally diagnosed with stage 3a triple neg. 4 lymph nodes cancerous in 2011. Treatment (Double mast., chemo and radiation) ended in March 2012. Found out I was stage 4 with a lung met in January…
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Lita57
I wanted to start a new thread for Lita, so she will only have to post on one thread. She has received some bad news this week. Let's all come together and walk with her through this. Lita, I posted on another thread that you posted on. Hope this is helpful that now you will only have to post once and everyone will know…
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MBC and Your Job -- whats your story?
We're looking for submissions about your experiences with a metastatic breast cancer diagnosis and managing your career. Did you find great support in the workplace from your employer and colleagues? Did you feel comfortable disclosing your diagnosis? Were there any unexpected reactions? How did you handle any…
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Please Read! Check Vit. D, 25-Hydroxy Levels
New research suggests that breast cancer patients with high levels of the vitamin in their blood are twice as likely to survive the disease than patients with low levels... The studies included a total of 4,443 patients with breast cancer and were performed between 1966 and 2010. All patients were followed for an average…
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For those on Ibrance, PFIZER Oncology Together can provide help
Pfizer Oncology Together is a first-of-its-kind program for patients taking Pfizer Oncology medicines that offers dedicated social workers called 'Care Champions' to help navigate the complexities that accompany treatment, such as identifying resources to help find emotional support, and workplace transition,…
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Is the Highest Dose Always the Right Dose for Us?
You may be interested in this article about a patient advocate-led survey which was presented in June at ASCO 2021. It's seen as the "first step" in determining whether there may be a different approach to treatment where people affected by metastatic breast cancer and their doctors collaboratively discuss the best dose…
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Black voices needed! Help make metastatic breast cancer research
Black voices needed! Help make metastatic breast cancer research more diverse by taking an anonymous patient survey about your thoughts on clinical trials (even if you've never participated in one). Survey closes July 15th. Go HERE to start the survey!
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Most W/ MBC Have Troubling SEs, Willing To Discuss Dosing
Most Women With Metastatic Breast Cancer Have Troubling Treatment Side Effects, Willing To Discuss Dosing Options With Doctor June 16, 2021 About 86% of women diagnosed with metastatic breast cancer had at least one bad treatment-related side effect, and 92% were willing to discuss options for different dosing levels of…
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Lets Talk About Oncologists
What do you look for in an oncologist? What is it about your onc that you like? Why I ask: My oncologist and her nurse are retiring soon. They've been with me for 10 years since I was first diagnosed. I got kinda spoiled, they were so good to work with in so many ways and I will miss them immensely. They are both over 70…
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Tukysa + Standard Tx Improves Survival in Advanced HER2+
Adding Tukysa to Standard of Care Continues To Improve Survival in Advanced-Stage HER2-Positive Breast Cancer June 15, 2021 Adding Tukysa to the standard of care of Herceptin and Xeloda continued to improve both progression-free and overall survival in people diagnosed with either metastatic or unresectable locally…
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Kisqali-Faslodex Combo Improves Overall Survival in Advanced HR+
Kisqali-Faslodex Combo Continues To Improve Overall Survival in Advanced-Stage, Hormone-Receptor-Positive Breast Cancer in Postmenopausal Women June 20, 2021 The latest results from the MONALEESA-3 study show that combining Kisqali plus Faslodex continues to offer better overall survival than Faslodex alone. Read more...
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Ibrance-Faslodex Combo Improves Overall Survival in Advanced HR+
Ibrance-Faslodex Combo Continues To Improve Overall Survival in Advanced-Stage, Hormone-Receptor-Positive Breast Cancer June 10, 2021 The latest results from the PALOMA-3 trial show that combining Ibrance and Faslodex continues to offer better overall survival than Faslodex alone. Read more...
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CA 27-29 testing
I have mets to my spine. My CA 27-29 had been running about 38-40 (normal 35) My Onc tested again 6 weeks after my total hysterectomy and it went to 134. At the time of the hysterectomy, they found many fibroids/ovarian cysts. Now, one month later he is testing again. He said if it trends up again "we will have to do more…
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Need your tips for taking a CDK 4/6 inhibitor
Tips for Taking a CDK 4/6 inhibitor such as Abemaciclib (Verzenio), Palbociclib (Ibrance), Ribociclib (Kisqali)—Before and During Treatment: Please share your advice for preparing to start treatment, dealing with side effects, testing during treatment, etc. Thank you!! p.s. this is to help us in a new content piece we are…
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Long term survival Her2 pos stage 4
Hi, I would like to hear from other long-term stage 4 survivors. Have any of you experienced ful remissions? What are your stories, what did you do personally to beat the odds? Below I will share my story. I am happy to expand on the integrative care I was/am receiving that has played a huge role in my well-being and…
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Newly diagnosed stage IV triple positive
I am 43 old mother of 13 and 9 year old girls and former police officer who was recently diagnosed with stage IV Breast Cancer. In the last two month I had a mammogram with a biopsy performed same day, been to a surgeon, received my pathology reported saying I'm triple positive with undefined cells, and told I was stage 2…
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Urgent call: Share your photo for Beyond Pink Website
Hi All, AstraZeneca is looking for photos and and quotes to be posted on their website, Beyond Pink: Sharing Our Metastatic Breast Cancer Story All you would need to do is: 1. sign release form 2. select photo to share 3. write quote (Per AstraZeneca: The quote can be anything you want to share with the community to…
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PROTON THERAPY
Has anyone had this done? If so, what did you have it done for Bone or Organ mets, and how was it as far as the actual treatment and side effects? Does anyone know if this is good for spine mets?
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CDK inhibitors may boost effectiveness of immune therapy in MBC
Just saw this and thought some of you might be interested. Cross posted from the research thread. CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer * Download PDF Copy Reviewed by Emily Henderson, B.Sc.May 10 2021 A class of drugs that inhibits breast cancer progression when used with…
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Gallbladder sludge and constipation-is there a connection
I had an abdominal MRI today. Everything seems okay except gallbladder sludge and fecal matter seen in whole colon. I’ve been dealing with constipation on all CT scans for a while. Is it from the gallbladder? I don’t have pain in my gallbladder, but I should say yet. My mom ended up having her gallbladder out later in…
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Please Take the MBC Alliance Surveys About the Pandemic
The Metastatic Breast Cancer Alliance (https://www.mbcalliance.org) is calling all metastatic breast cancer patients to take two surveys about your experience during the pandemic to help doctors improve care #MBCconnect Get started here. Thank you for your help on behalf of the Alliance.
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Stage IV breast cancer and Leptomeningeal carcinoma
Hi. I have a question. I was diagnosed in October with Leptomeningeal and stage 4 bc to my spine and pelvis. Had methotrexate and then switched Drs and had proton radiation. Went to dr yesterday I and she said I should either do Xoleda or try for a clinical trial. My question is Why do these treatments and feel worse when…
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Anyone know anything about Resolvin?
Hi all I read an article about chemo and targeted therapy being a two edged sword The cancer cell debris caused by therapy causes inflammation that can trigger new cancer cell growth!!! The body needs these Resolvins to help the system deal with the cell death debris. Anyone got any input? Ann
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Skin mets
My breast cancer has moved to my skin. I have had radiation to my chest and my back. The skin mets have returned. Some are small bumps and others are huge places that seem to be spreading. The radiation did not work. It only caused a lot of pain for me and loss of my skin. I was taking Xeloda with the radiation. In…
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Kadcyla/ other antibody conjugates and icing/ cold capping ?
wondered what was drug's pharmacology - does it stay where it has got to during IV infusion making it reasonable to use icing/cold caps with it or does it recirculate during it's presence in the body ( half life 4 days or thereabouts) making it pointless ?
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Stiffness after spine radiotherapy
Hi again. So after been in chronic back pain what i thought was down to my recent reconstruction, it was the cancer returning. Spine,pelvis,liver and nodes. Diagnosed 3 weeks ago. I went from bed bound in hospital, they managed my pain and i was pottering around with a walking frame. Im 47 and active usually. 2 weeks ago i…