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Information on GATA 3+ Cancer
Hello Friends, Thank you for accepting me in the group. I am ER+, HER2+ and GATA3 +. I was recently diagnosed (December 12, 2022) with Stage 4 Breast cancer with metastasis to Bones, lymph nodes and spleen. My chemotherapy regimen includes Trastuzumab(once every 3 weeks), Paclitaxel (every week) and Zoledronic acid (every…
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Metastatic or Terminal
Some posters have pondered what to call it. Many posters to this forum have wondered about this. When I tell people that I have Stage 4 Metastatic Breast Cancer, I get a whole range of reactions. Many do not know what Stage 4 means - to them, either you have cancer or you don't. Metastatic (it's all Greek to me) is usually…
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Has anyone been on Herceptin more than 15 years (or less)?
On and off this forum, I notice that many of you have been on Herceptin for a long time, When I was first diagnosed denovo, I started out with Herceptin, so it's been 15 years for me on the same drug. I receive it now every three weeks, and I've taken arimedex/anastrazole every day all that time, too. At the tine, I was…
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Kisqali Exemestane Xgeva Lupron
I am starting this regiment tomorrow and am hoping there are others out there that are currently on this same protocol or have been and can offer advice and knowledge of side effects, etc. pretty nervous about tomorrow, keeping a positive outlook and want to do anything and everything I can do to manage side effects and…
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Liver mets: resection, ablation, SBRT, Y-90, anything else?
I'm interested in who has had local treatment for liver mets and what was your experience and outcome. I've been talking about this with my onc, and he seems a little hesitant. I have my regular appt. for a 2-mth MRI of brain and followup with rad onc. I plan to ask him about the possibilities. I think that some of the…
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Kisqali Exemestane
Hello, Anyone on a Kisqali and exemestane combo? I'm just finishing my first cycle--after 8 rounds of paclitaxel was getting to be too much for me, my onco and I decided to try this oral chemo. Noticing my hair thinning, which is extra upsetting as I cold-capped with the paclitaxel expressly because I did not want to lose…
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MBC Approved Treatments, Dealing with Side Effects, and More
Are you facing a treatment change and questioning what drug may be next on the list? Dealing with treatment-related side effects? Or wondering about cutting-edge research? If you answered Yes to any of these and want science-based information at your fingertips, read my book, "The Insider's Guide to Metastatic Breast…
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A break from BCO
Dear Friends, I'd like to start by wishing you all a happy, merry everything as we approach the holidays! BCO has been a wonderful place for me over the years and I truly appreciate the support and input I have received. Some of you may be aware of the fact that over the course of 11+ years I have been the recipient of…
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Digestive side effects from Verzenio
Hi there. I was initially diagnosed with Stage 3a HR+, Her2- breast cancer at the age of 39 (2004). Treatment included a mastectomy with 23 lymphnodes removed (1 positive one), typical AC/T chemo regimen, radiaction, and Tamoxifen for 5 years. I was in remission. Fifteen years later, almost to the day, I started to have…
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Kisqali + Hormonal Tx Better as 1st Tx for Advanced-Stage BC
Kisqali Plus Hormonal Therapy More Effective Than Chemotherapy as First Treatment for Advanced-Stage Breast Cancer Dec 19, 2022 Pre-menopausal women diagnosed with advanced-stage, hormone receptor-positive, HER2-negative breast cancer got more benefits from Kisqali and hormonal therapy than chemotherapy as a first…
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33, TNBC, skin mets, and chest wall recurrence.
Hi All, not really a point to make but at 33 this is an isolated club to be a part of. Just want to share my experience, thoughts and treatment incase anyone is going through what I am. I found a lump in 2020 at 31. Was told it was nothing. 6 months later I was diagnosed with stage 3, TNBC. I did 4 AC, 4 Taxol, 1 failed…
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Enhertu's Benes Conf. for HER2+ MBC; Could Help Early Stages
Enhertu's Benefits Confirmed for Metastatic, HER2-Positive Breast Cancer; Could Help Treat Early-Stage Disease Dec 14, 2022 Updated results from the DESTINY-Breast02 and DESTINY-Breast03 studies confirmed the benefits of Enhertu for previously treated metastatic, HER2-positive breast cancer, and results from the TALENT…
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Chemo v. Targeted theraphy
Hello, this month I was diagnosed with MBC, pet scan shows bone met on several locations, 1.7 lungs nodule, and met on my chest lymph nodes. I am ER+(98%), PR-, HER2-. Biopsy on my fibula confirmed as cancer. My Onco recommended Abraxane chemo for 3 months and Zometa every month for 5 months. I saw my 2nd opinion doctor,…
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21 Years of Stage 4 MBC de novo!
Yay me! Today is the first day of my 21st year after being diagnosed with Stage 4 MBC de novo! Originally ER+, PR-, Her2+++ with liver mets. I had a recurrence in 2 chest nodes 11 years ago, which changed me to Her2- Somatic. I have had A/C, Taxotere, Gemzar, Herceptin, Aromasin, Faslodex, Kadcyla, Poziotinib, and now on…
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Podcast: Experimental Capivasertib Promising for HR+, HER2- MBC
Experimental Capivasertib Seems Promising for Advanced-Stage, Hormone Receptor-Positive, HER2-Negative Breast Cancer Dec 15, 2022 Dr. Nicholas Turner explains research looking at capivasertib, a new targeted therapy medicine. Researchers are always looking for new treatments for advanced-stage breast cancer. Dr. Nicholas…
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Podcast: Overall Survival in Enhertu vs Kadcyla for HER2+ MBC
Enhertu Offers Better Overall Survival Than Kadcyla for Metastatic HER2-Positive Breast Cancer Dec 9, 2022 Dr. Sara Hurvitz discusses new overall survival results from the DESTINY-Breast03 study. 2021 results from the DESTINY-Breast03 study showed that Enhertu (chemical name: fam-trastuzumab-deruxtecan-nxki) more than…
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Podcast: What I Get From Breastcancer.org Meetups
What I Get From Breastcancer.org Meetups Dec 10, 2022 Breastcancer.org Community Member Vanessa Onsurez talks about her diagnosis, #ThisIsMBC, and Meetups. Vanessa Onsurez, who was diagnosed with metastatic breast cancer in 2021, explains the #ThisIsMBC project at the 2022 San Antonio Breast Cancer Symposium and the…
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Paid survey
Hi! As you know, I talk highly of RC Horowitz and have been taking surveys with them since 2020. I am not employed by them. They are looking for participants for another survey. The requirements for this one are as follows: HR positive / HER2 negative NOT currently taking Hormonal/Estrogen therapy but has taken in the…
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Podcast: Elacestrant Seems Effective for HR-Resistant BC
Experimental Elacestrant Seems Effective for Breast Cancer Resistant to Other Types of Hormonal Therapy Dec 8, 2022 Dr. Virginia Kaklamani explains the latest results from the EMERALD trial comparing elacestrant to the standard of care. Doctors are looking for new treatment options for people diagnosed with metastatic…
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Podcast: What Pts Want Drs & Resrchrs to Know Abt Living W/ MBC
What Patients Want Doctors and Researchers to Know About Living With Metastatic Breast Cancer Dec 7, 2022 Metastatic breast cancer patient advocates Christine Hodgdon and Stephanie Walker explain why the viewpoints of people living with metastatic breast cancer need to be incorporated into research. A number of issues…
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Newbie Questions
Hello All! I am new here....some background. Family has history of BC. Can be traced back to my great grandmother. No genetic mutations found. Had BC first time 2006 (bilateral mastectomy with implants, salpingo oopherectomy, 3 rounds of taxol), recurrence 2013 (mastectomy redone, ACT(taxotere not taxol) DIEP Flap,…
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Question about new treatment for MBC
Recently diagnosed with MBC after removing two lymph nodes near liver which confirmed related to original lobular ILC in 2013. My oncologist has put me back on letrozole 2.5 and I will have blood work and pet scan on 12/6 to compare with pet scan in July. Then I may begin Ibrance, Verzinio or Kisquali. My question is does…
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CK4/6 comparisons
Of the three CK4/6 drugs which are Kisquali, Ibrance and Verzinio is there one that is the most effective when used with letrozole? Also is there one that has fewer side effects than the others. I am anticipating that my oncologist will put me on one of these and trying to gather info to discuss my options. Thanks for any…
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Weekly Zoom meet up for those of us still working
The Mods contacted me via private message to see what time and day would work best for those of us who are still working and finding it hard to participate in the current stage 4 weekly Zoom calls. They are trying very hard to get a meeting that will work for us. If you could please post which day(s) and time(s) would work…
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HER2+ MBC. Anyone 5 years out?
My name is Peoy. Singapore Chinese. Dx Oct 2022 with 8 sclerotic bone mets from T8 to pelvis and lymph nodes. My cancer cells have morphed: ER80%+ to 5%+. PR+ to -. Her2+ remained 3+. Just started Taxol+Herceptin+Perjeta. Xgeva mthly. My MO said median prognosis is 57mths. I also hope to discuss HER2+ MBC treatment lines.…
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Gemzar
is there anyone here on Gemzar? Had my first treatment on minday
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Lynparza/Olaparib Anyone?
I'm looking to share side effects or just any updates on Lynparza / Olaparib. I just started targeted therapy on Jan 12th. Aside from a little heartburn at first (helped with OTC pill), I've now started some daily Immodium, which the pharmacy sent WITH the Lynparza. Lol. I've started to just feel plain odd and very…
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Fall 2022 New Covid Shot?
I was just curious if anyone had got it yet. My MO told me a couple of months ago to go ahead and get another booster but by that point, it made sense to wait until the new Covid shots came out and hopefully get better protection against the new strains. However, I am not sure from what I am reading if the Covid vaccines…
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DVT’s
I wasn’t sure which thread to post this on, and I didn’t see one specific to the topic. Have any of you had DVT’s? I’m freaking out somewhat. On Wednesday morning, I noticed my left leg was swollen when I put pants on and they were tight on my left calf. It was swollen and felt tight, but no pain, discoloration, etc. I did…
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Medicare questions
This is pertaining to Medicare in the U.S.---- I will be eligible to start Medicare in January 2021--- 2 years after being approved for Social Security Disability. I do not know anything about Medicare as I am not close to regular Medicare age (I am 50 years old). I want to do some research now in preparation for applying…