Taxotere, Carboplatin and Herceptin
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Hi everyone,
I'm new here. Hope you don't mind if I jump right in. I'm wanting ot hear from people who have already finished TCH Chemo. Was the first treatment an indicator of how subsequent treatments will be? I've read lots of people taking precautions before treatment for nausea, heartburn, etc etc. Should I take these meds beforehand just to be on the safe side or should I wait. Is there a cumulative effect or is the experience consistent. Is each treatment the same experience. I'm just trying to be prepared. My Onco. said not to take any over the counter meds, anything I need will be prescribed.
thanks in advance Jamie
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Michelle.. Amy is right about the PICC line, it is a permanent IV on the upper inside part of your arm. I had one that was intended to be in for 6 to 8 months according to the doctor, but they had to take mine out after 2 months because I got a blood clot in my arm. Most people here have a port and I will probably be getting one too in a few weeks. I should have gotten one in the first place but I didnt know which would be best and the doctor said he wanted me to have a PICC line. The PICC line does need weekly bandage changes and cleanings and flushing of the line, so it is more trouble. and also you can't get it wet so must wrap it to take a shower.0
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Pinkmama - Wow, you asked a lot. Please go back and read thru this thread, you will learn a lot. Yes, in SOME instances the effects are cummulative. Yes, chemo has side effects tha can be managed - See the thread on the chemo kit, But your questions are really to broad to give good answers. I know you are scared now, but get nour thoughts together and we are here to help.0
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Thanks Lisa, I will read the thread. I'll start with one question:
When I go for my 1st treatment, (which is in 5 days). Lets say I'm wiped on day 4, 5, & 6 and cannot work, will it pretty much go the same way after the 2nd treatment? Is it predictable?
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Pinkmama - I think that not everyones experience is the same. I went in believing my oncologist when she told me that the 1st one would be the hardest, and the the ones to follow would be easier. It was quite the opposite for me. Each one actually got worse, and I didn't always have the same side effects each time. And with each one, it would take me longer to "recover". I was determined through it though, to stay as active as possible. I didn't do much as far as exercise during the week following chemo, but in the 2nd and 3rd weeks I felt well enough to play tennis, which is my therapy. I can't do it for hours like I used to, but I can do it! I am just a week and a couple of days out from my last TCH.0
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I'm just a week past my 3rd TCH tx. The first one was the most intense emotionally b/c I didn't know what to expect. I learned some medical/supplement stuff to do after that so the 2nd and 3rd were a bit better in that way. However, I think I bounced back slower after the 3rd one, so maybe it is catching up to me.
But generally, I'd say they were pretty much the same (so far).
I did have that awful acne breakout after the first one, which only happened that one time, thank GOD because it was horrible.
I'm trying to take them one at a time and not compare too much. I'm glad I have three done, but I know I have three more to go. It's a mental game for me, more than physical, mostly.
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Pinkmama...Remember, not everyone's side effects will be the same AT ALL. I have had 4 treatments so far, and for me, I am wiped out day 3-7 and I do not work that week. Then I work half days the following 2 weeks. I think it depends on what kind of job you have too. I am a hairstylist and on my feet all day. Seems like my SE's are about the same each time with a new one added on each time as well. I am not nauseated because I have good meds for that, I am in chemo-fog where I feel out of it, very exhausted and can only do an activity for about 10 minutes before getting too tired. I get heartburn really bad when drinking all of the water, but I took Prilosec OTC the last treatment and that helped a lot. And now I have a lot of night sweats. What I do is write down my side effects each time on each day to know what to expect and compare with for the next.0
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Lisa and Amy: Thanks for the input...I have been researching ports and the PowerPort Implant seems to be the most popular one out there (at least based on input by others on the forum)... I'm just hoping my PS will give the ok and it won't interfere with the immediate recon. I cannot see why it would since immediate recon with TE is frequently done but, of course, I do worry. Hate the waiting and unknown...I would rather be in the thick of it actively fighting (for better or worse) then to be in limbo land wondering and anticipating...
Edited to Add: ccbaby thank you for your input as well...apparently my screen was not updated when I logged back in and I totally missed your post. I am having a bilateral mx and I am scared I'll have to delay recon. It sounds stupid to be worried about delaying recon, but I have come to realize in the last few weeks just how much I associate my breasts with how I feel about me as a woman and being feminine...
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o2bhealthy - I got my Power Port about 3 weeks after my bi-lateral. When I had the bi-lateral no one knew I was going to need the port, so it was not dicsussed, however. I had simultaneous reconstruction in the same surgery as the bi-lat and it was a LONG surgery - about 6.5 hours, so I dont know if they would have added another procedure or not.
Pinkmamma - I agree with Amy that the first tx was bad because of the unknwon and not knowing how to manage some of the se's. But for me, each treatment got a little worse and by #4 I was wiped out. I think #6 was managble only because I was mentally phsyched up because I was finished, But everyone is different and not every gets the same SE's. But the bottom line is, you can do it. It is not something you would wish on your worse enemy, but you can do it and you will survive. Just remember the wonderful bunch of people on this thread are here for you.
Lisa
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Thanks guys for the replies.
Tennisgirl: I am happy to hear you were able to exercise (play tennis) during your treatment. I do aerobics and want to be able to continue even if it is only once in awhile.
AmyisStrong: I agree about the first one probably being the worst one, since you don't know what to expect. I am full of anxiety. (sigh).
ccbaby: I am also a hairstylist and I LOVE my work and don't want to stop. I have my business at home and I'm fortunate that I can move the schedule around as needed. I am so relieved to hear that I will be able to work. It gets me out of Cancer World. I will keep a log of everything so that I can refer to it for the next one.
Lisa1964: Thanks for the encouragement and the info. I am worried about the first one (the unknown) Thank God I have this board. It is my lifeline.
Jamie
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I wonder if any of you can help me with something that's causing a great deal of anxiety for me, but probably sounds totally ridiculous to everyone else? This is really freaking me out guys!!
I'm on 12 weekly doses of Taxol and Herceptin with a heavier dose of Carboplatin added in every third week. I began treatment on May 6th and have completed 5 doses of T & H and 2 of T, C and H together. Right now I'm at day 12 since my 2nd Carbo and 33 days into treatment. This coming Wednesday I'll be halfway through treament.
I was told I would lose my hair within 21 days of my first treatment and I was prepared as anyone could be for something like that. I bought my wig and headcovers and started waiting just like everyone else here.
Now here I am, 33 days after treatment began and not one hair has fallen out of my head and it's scaring the every lovin' crap out of me that the Chemo is NOT working. If it can't even kill my hair cells, how the heck is it killing cancer cells!?!??! I know with weekly Taxol and Herceptin (thanks to NanaA) that sometimes the hair just thins, but I was told with the Carbo I would "definately lose my hair within 3 weeks".
Each week I go in for treatment and the Chemo nurses and the Onc. are shocked by the fact that I haven't lost my hair. They just shrug their shoulders and assure me it'll start happening "by next week", yet nothing happens.
I know this must sound like I'm looking a gift horse in the mouth, but this is scaring the heck out of me. The anxiety of thinking that Chemo is not working is freaking me out.
I have had some other side effects including fatigue on days 3 & 4, severe heartburn, feeling as though my entire body is bruised (sore to the touch), but my blood counts are in the normal range (barely) and I haven't had to take the Neupogen shots that were prescribed for me 3 weeks ago. I feel as if my body is resistant or something.
I mentioned this to the doctor the week before last and she sort of blew me off saying the hair loss will absolutely happen!
Has anyone else either had this experience or heard of someone having an experience like this? Please understand that I wouldn't ask unless it was causing this much anxiety, but it is. I'm not looking forward to losing my hair, but the idea that the Chemo might not be working is really upsetting me! HELP!!
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I can totally see how you are feeling. My hair didn't fall out as scheduled but took a little longer (not as long as yours though) and even then, a lot of it didn't fall out and is starting to grow back. I had it buzzed when it started to fall out, but what remained is growing (slowly) a little longer. I felt somewhat of the same way and asked about it as well. And they said the same thing - everything's fine, it's working.
I don't have any answers unfortunately except to say that I relate to your fears. The answer I would be looking for from the docs isn't "it will fall out eventually" but rather an assurance that the chemo IS working regardless of how your hair responds. That is the info I would push for (taking the focus off the hair and onto the cancer cells). I am so sorry you are going through this. I don't think you are looking a gift horse in the mouth AT ALL. You want to know that what you are going through is effective. And seeing the medical staff be so shocked when they see you with hair each week can't be helping.
Perhaps next week you can approach them again and push past the whole shocked thing and tell them calmly, "This is causing me significant anxiety and I need some answers. It is affecting my quality of life." (they love that quality of life thing!) I can see how they can shrug it off, but you are going to have to push them for data or evidence or SOMETHING that reassures you. YOU ARE WORTH IT and your peace of mind is worth it.
Good luck and please let us know what you find out.
Just another thought - there is a thread called "Hair Hair Hair' that is all about hair questions. I wonder if you post there, if you might find some answers because different people read that section.
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Thanks for being so understanding and helpful Amy!! It helps to know that even though are situations are a little different that you didn't experience total hair loss either. I'm also getting the same response you did: "Don't worry, the Chemo is working". How can you NOT worry!!?? As I said....if it's not killing my hair, how can I be sure it's killing the cancer!
I'm absolutely going to push harder when I see the Onc again. I'm getting tired of the "don't worry" and bemused looks on their faces. This is scaring me! This anxiety really is affecting my quality of life!!
Thanks also for the suggestion about posting this in the "Hair Hair Hair" topic. I'm going to go over there right now.
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Pinkmama...That is so great that you have your business at home. That should make it much easier for you.
Michelle... which type of recon are you going to get?
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Shadow: I am going in on Friday for #6-my final treatement. I never lost all my hair. I still have a good deal all over my head, though it is short b/c I had it cut short. One day, it just sort of stopped falling out. I had a month off in between #1 and #2 due to an infection. I still wonder if that's why it never all came out. Everyone is different and your treatment is different. I am on TCH every three weeks.
What concerns me the most is the approach of your onco. You're fears are justified and they should recognize that. You need to have all your questions and anxieties addressed by them! Is there another doc in the practice that you can meet with?
Maggie
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Shadow, I answered you over on the hair thread, but I agree with everything the ladies said here too.
Pinkmama - the more active you can stay the better off you will be. I am a cosmetology instructor and I worked all thru treatment except on the infusion week. My tx's were 3 weeks apart. Week 1 I would stay home, Week 2 back at work and by the end of week 2 and all of week three I worked my normal schedule and rode my horse.
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shadow, I was told that the intensity of side effects doesn't indicate whether chemo is working or not. Some of our bodies just react differently to the chemo drugs. I lost my head hair but never lost eyebrows or lashes. Perhaps not getting the triple dose of taxotere with the carboplatin is letting your hair hang in there.
o2bhealthy, I had my port put in a few weeks after my lumpectomy. I asked when I went in to get my port why they didn't just put it in during the lumpectomy. The radiologist said that they prefer to put it in in radiology where they have better imaging to see that they are getting the catheter in place properly.
Jamie, my symptoms during cycles stayed similar. The first one was a little different because I didn't get Neupogen at first and my white cell count went really low. I got a fever from low white cells so then the oncologist prescribed Neupogen to bring them back up. On the rest of the cycles, I got Neupogen to start a few days after chemo so that wouldn't happen again. Other than that, my bad days always started about the same time but they lasted a bit longer on the later cycles.
Except for the last cycle, I always felt okay during week 3. My magnesium had gotten low by the end of chemo and I was anemic so that time I didn't feel good until I got a blood test and they gave me a transfusion and magnesium.
The only medicine that I took before chemo was the prescribed steroid, Decadron, and anti-nausea pill, Zophran.
I didn't take any over the counter medicine until I had symptoms that needed it. What I used was mostly immodium because chemo tended to give me diarrhea and sometimes Aleve because bursitis that I had before starting chemo was bothering me. Some other people have had constipation so which way your stomach will go is difficult to predict and its best to have both on hand. Some have acid reflux, but I didn't. I had dry eyes at times so I had eye drops on hand. I use the ones that are just saline in single use vials because they don't have preservatives. Some people get drippy eyes instead. At times during chemo I had dry skin so I had moisturizer for that. It is nice to have one that is unscented because smells can bother you during chemo. At one point, I had dry skin on my cheeks which was getting a little chapped and at the same time some pimples by my nose.
I did work through chemo just taking a few days off or taking a nap some days. I work from home most of the time so I could do that. On the third week of some of the cycles I went on business trips.
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Amy, the wedding date is about 10 months after you finish chemo, right? I think most people have a good head of short hair by then. Herceptin may slow hair growth, but it doesn't stop it. Like Lisa, I'm a bit less than 4 months after my last chemo. My head is fully covered with a "marine hair cut" - hair about 1/2 inch long. I expect that in 6 months I should be able to have a nice short woman's cut.0
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Lisa: what kind of recon did you have done? I was told it would be 4-5 hours for my surgery.
bluedasher: thank you for the heads up on why they waited for your port...it makes sense, I'm just impatient...
ccbaby:I am having immediate recon with TE after my bilat mx...
shadow: I can only imagine how scared you must be and how frustrating it is to feel like your care team is not listening or validating your concerns. I agree with Amy and Magnola - see if there is another doc in the office you can talk to...your in my thoughts and prayers...
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Catching up after serveral days in bed with low white count and fever.
You ladies are amazing! The support and guidance here is extraordinary. I know I post this often, but each time I return to the board, I am overwhelmed by the informative and caring words that are offered here. Bluedasher, you are always so fantastic with technical information; you have taught me so much. Rita (Bold), you have such a lovely way of encouraging us to be spiritually healthy and balance that so nicely with your medical background. Lisa and Jamieh you are fantastic cheerleaders with so many wonderful suggestions. Swampy, I am so very impressed with you--when you first started your treatments, I couldn't even begin to imagine how you were going to work out the logistics of your treatment, but you seem to indeed be stronger, meaner, and happier than than your chemo treatments--you are an inspiration! Tennisgirl congratulations and thank you for letting us know what it feels like to be at the end of the Herception treatments.
I have laughed, cried, fumed, and smiled through four pages of posts. Congratulations to you all for all the great things that are happening in your lives, and thank you to the ladies that are willing to vent--understanding that venting is essential to our process and there is no better, or safer place to vent, was an important lesson for me to learn.
Rita, Shari, and Cakelady I am so glad that you are feeling better. I pray for Cupcake and hope to hear from soon.
Cheers!
Cloud
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o2bhealthy - My recon was simultaneous with the bi-lat mx. I have silicone implants. I already had implants before bc, so I had the cavity in place and was able to by-pass the expander phase.
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Hi Taxotere Girls !
Where did I go wrong?
Had finished 4xAC and had my first Taxotere 6 days ago
Day 1 was fine -day 2 was fine -thinking I am going to get away with this lightly day 3 wham! I am unable to walk -the soles of my feet feel like they have been beaten with a rubber hose and I have 10x flu pains -my mouth ,throat and all my nether areas sore-took antinflammatory meds -its now day 6 and I am not too bad can walk in crocs only but feet and bones still sore. This was really bad I was ill-much worse than the AC even the nausea was preferable with the AC than this -and the neulasta shot was tolerable before.
So Im thinking maybe I didnt drink enough water(which I hate now )-maybe that Claritin( i was given Zirtex )-or more steroids-any suggestions -any other recipes for the mouthwash-cant get Biotene here. Un bearable shooting pains in the lumpectomy breast.
Any one got any suggestions apart from seeing the onc again and "noone has ever comlpained of that before" makes me out to be a wimp!
Would ice on my feet help next time?
Have a good day all
Anna
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Anna, all of your symptoms are normal. Call the doc and get a prescription for Magic Mouthwash. I am 17 weeks post chemo and my feet still hurt. You really need to talk to a doc about the shooting pains in the lumpectomy side. Good luck.
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Anna, I have had feet pain for a long time even before Cancer and still have it when my fibromyalgia is acting up. You can get rebound pain from the steroids (decadron) and that is when I had my worse arthritis pain ever. I am in the trows of a arthritis rebound pain now because I get a steroid shot every 3 months form arthritis doc and it just wears off too soon. Makes me wonder if it is worth getting when the rebound pain hits. I am not sure why a persons feet hurt like that. I never even asked my rheumatologist. I find a supportive shoe helps since I am a bank teller and work on my feet. I did have to go to court a long time ago to get to wear the athletic shoes for work but I got it with doc prescription.
I am now 6 months past TC but still taking Herceptin and this was supposed to be my last treatment this month but last time the doc said I would have to go past a year on it but would not discuss why. He just wanted me to get a heart check up asap but that turned out good except for 2 valves that were a little less tight but the cardio said it was not bad considering all I had been through and age. It can improve after Herceptin but my blood output was in the normal range which is 50 to 70 percent. I am 55 so lower than it was but still acceptable. We will see June 17 how much longer it will be on Herceptin and why. I am having a difficult time breathing since radiation which could have caused it.
I have a port and I am so glad I have it. I got several blood transfusions and they can put it in the port. I was not given a choice but I am happy with it even though it sticks out more than some do. I am bony there but not skinny and also mine has turned a little so it is not flat like most. They said losing weight is probably why. I had mine put in 2 weeks after surgery and then a week later I started chemo. My friend had a problem with hers on the first treatment but she had another put in and it worked fine. She was really upset about it but then things happen sometimes. She had her next treatment the next day after having it put in.
My hair did not completely fall out but enough that I had bald spots so I had it burred off and wore a hat or scarf. I was so glad when my hair filled in enough to not wear anything and a lot of my customers like my short hair. It does not seem to be growing much but everyone says it is. I think the top is growing slower than the sides and back. My last TCH was early Nov so it has been a while but I would not mind being in pictures at a wedding like this. You could get extensions I guess if you are not happy about the hair length by then.
I agree with the ones that say everyone is different on how you will react and when to treatments. Mine always hit me on the weekend because my treatment was on Wed. each one was different but once I figured out what to take and when it went better. Still sick but knew how to treat it. I had diarrhea mostly but I did find out if I had my bowels moving good before the tx then it was easier. I got constipated the week before 4th tx and I had a rough time. So my advice to newbies is to take a stool softener or a mild laxative a couple of days before the tx. Senacote has a mild laxative and stool softener you might try. I am not sure how to handle the constipation like some had but just to do what they did and water, water, water. You must drink water. After the tx you have to drink lots of water or non caffenated stuff ( juice etc. to wash it out) My friend was not told this and got kidney damage. He had lots of chemo though. More than I ever had. Just remember water even if it does not taste good to you.
Okay I am through preaching. I heard from Cupcake a while back and she was doing good and had gotten a new convertible from her husband. She may be driving the wheels off it. LOL. I hope this is the case and not that she is ill but her surgery had gone well at that time.
Carolyn
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Michelle--I had my port put in the day of my mastectomy. It was a different procedure--before the actual surgery, but the same day. I also had immediate reconstruction. It's a little sore at first, but by the time I had my first TX, it was fine.
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Anna, you would be different from us because we didn't get AC before and we got/get Carboplatin with the Taxotere which causes its own set of symptoms. Taxotere can cause nerve pains or numbness in the extremities. I only had a bit of numbness and tingling in my fingertips but others get the foot pain. It is commnon to feel fine for the first couple of days after chemo and have the symptoms hit on day 3 or 4.
Shooting pains in the breast may be due to the nerves regenerating after surgery. I've had those from time to time. I was told that could happen during the year after surgery. I had it mostly during radiaiton which was about 6 months after my lumpectomy.
You could try putting some lemon in the water. I'm getting over a cold and find it soothing to put a teaspoon of honey and some lemon in some hot water. Soup is another way to get the fluids you need. I found I could drink beef or chicken broth when I wasn't interested in other foods during chemo. If you have mouth sores, you should ask your onc for a Magic Mouthwash perscription like Lisa said. I had a cup of ice chips to suck on during the Taxotere infusion to try and prevent mouth problems and that worked for me.
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Hi Magnola:
First of all CONGRATULATIONS ON YOUR LAST TX!! I'm so happy for you!! Thanks for the input. So nice to know someone else didn't completely lose their hair. I'm only halfway thru treatment so it's possible I'll end up like you, losing some of my hair but not all.
Thanks for the input on the Onc as well. Honestly, I think she really believed all my hair would go. I spoke with her this morning and she said I had not conveyed how upset I was. She could be right. I sometimes have a problem allowing myself to appear very upset. I tend to hide things and sometimes I don't come across as upset as I really am. I appear casual. I can't help it. It's just the way I am and it's not doing me any favors in treatment since I tend to delay asking for help and I "suck it up" until I can't take it anymore. Stupid, I know. She also said I was "the exception to the rule" and didn't want to give me false hope at the beginning of treatment since a huge percentage of people do lose all their hair. She said it still may thin out or go completely. We won't know it till it happens.....or doesn't.
Hi bluedasher:
I think you've just hit on what may be the reason for my NOT losing my hair. I was told today by the Onc that there are much less side effects with the weekly Taxol vs. the every 3 week. She also confirmed just what you said: That the intensity of side effects has nothing to do with whether the chemo is working. That was apparently an old school way of thinking and has been proven false in recent years. You live and learn.
Dear o2bhealthy:
Thanks so much for your input and for caring. I really appreciate it. As I said earlier, apparently I don't convey my discomfort and upset very well when I'm with the Onc. She was very supportive and caring when I finally let it fly this morning. It's partially my own fault. I spoke to my husband and he agreed that I tend to NOT show how upset I am when I speak with the doctor. I've learned my lesson. I'm going to let it fly more often and NOT suck it up anymore. The Chemo nurses on the other hand, did absolutely blow me off. I'm going to need to be stronger with them. Polite but more firm in terms of my concerns and discomfort. I'm not going to sit around and worry about something anymore. If I have a problem, the Onc is getting a call. If I'm not satisfied with her response, I'll see her partner or another doctor. Whatever it takes.
Hi anna:
Don't let them get away with that "no one every complained of this before"!! Don't be a mouse like me!! It's caused me more stress than the Chemo! Do or say whatever you need to in order to get your point across!!
To Whomever Was Asking About the Mouth Sores:
Sorry.....I can't seem to locate your name. I got the mouth sores right from the first treatment. I used a combination of Maalox and Benydryl (1 tsp of each mixed together 5 times per day) and it kept the sores at bay for the first 3treatments. By # 4 it wasn't working as well and I was given a prescription for Nystatin which worked wonders. They were gone in a couple of days. It's a liquid. You swish and swallow 1 tsp 4 times a day. Hope that helps.
My very best to ALL! May your side effects be few!!
Love, Kathy
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Linda~ (Denali) I hope you where able to get treatment today.
I got my herceptin only today BUT I am back for a blood transfusion on Wednesday. My RBC are in the toilet again. I just hope sitting for 6 hours makes my blood work look wonderful and helps me recover from surgery easier.
Does everyone here get Hercepting pre-meds ?? I got benedryl today and I still feel out of it 5 hours later. I had them cut it back to only 1/2 the normal dose but I feel horrible still.
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Jamieh - I'm still in the TCH tx phase but my chemo nurse already told me that when I get to the H only, they tend to keep you on the Benadryl a a pre-med, and that it is unnecessary after the first one or two. She said that for women who have things to do afterwards (like who doesn't?), we should ask to eliminate the benadryl from the drip for subsequent treatments after the first few. That's what I intend to do. The Benadryl really knocks you out!
Shadow- Good for you for realizing this and changing your approach to get the results you want. What I have found works, and suggest you consider, is not necessarily to ACT more emotional (b/c they hate seeing emotions and can stop hearing what you are saying if you get too upset), but to use strong language. (No, not THAT kind!
) For instance, I make eye contact and say "This is very distressing to me and I need to ....." whatever you need. At one point last tx, they wanted some new nurse to access my port and I wanted the nurse I have come to trust to do it. They said she was busy and I said I would wait. The nurse made a little joke and laughed it off and I said "No, I'm not laughing here." And they went and got the nurse I wanted. I think a calm demeanor with strong, pointed language (if you can manage it) is the way to get results. When they were blowing off my huge acne-like breakout, I finally called and said "I know you want to give it a few more days, but this has become a quality of life issue for me and I do not want to live with it" and they called in an RX right away. (Now to be fair, my skin turned the corner that day and I never did need to use the Rx, so they were right, but I had HUGE peace of mind knowing I had the medicine on hand if I needed it.)I think that firm and direct language that says exactly what you need is the best way to get results. There was one time with my oncodoc that I told him i wanted to have an eye-to-eye discussion and I made him stop looking at his laptop and maintain eye contact because I had some serious things to say and i wanted his full attention. He did, and it ended up being the best interaction we have had yet. But usually, his head is in the chart and I had to insist in order to get that.
So keep going in the direction you are already. Just don't feel you have to ACT all emotional. Just verbalize the strong emotions that surround the issue & I believe you will get what you want.
GOOD LUCK! This is harder for some than for others. For me, my challenge is to keep my mouth SHUT!
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Jaimieh - I don't get any pre-meds for Herceptin. I never got Benedryl. For TCH, my premeds were only the oral Decadron and Zophran. I would hate to get Benedryl when I don't need it.
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