natural girls
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Below are articles on the anti-cancer properties that I have found on Pubmed.com, a digital library of 18 million articles. The evidence is overwhelming!
1. Journal: J Ethnopharmacol. 2009 Jan 21;121(2):241-7. Epub 2008 Nov 8.
Title: Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potential.
Authors: Gautam M, Saha S, Bani S, Kaul A, Mishra S, Patil D, Satti NK, Suri KA, Gairola S, Suresh K, Jadhav S, Qazi GN, Patwardhan B.
Abstract summary: To study the effect of standardized Asparagus racemosus root aqueous extract (ARE) on systemic Th1/Th2 immunity of SRBC sensitized animals. RESULTS: Treatment with ARE (100mg/(kg b.w.p.o.)) resulted in significant increase of CD3(+) and CD4/CD8(+) percentages suggesting its effect on T cell activation. ARE treated animals showed significant up-regulation of Th1 (IL-2, IFN-g) and Th2 (IL-4) cytokines suggesting its mixed Th1/Th2 adjuvant activity. Consistent to this, ARE also showed higher antibody titres and DTH responses. ARE, in combination with LPS, Con A or SRBC, produced a significant proliferation suggesting effect on activated lymphocytes. CONCLUSION: The study suggests mixed Th1/Th2 activity of ARE supports its immunoadjuvant potential.
2. Journal: J Agric Food Chem. 2004 Apr 21;52(8):2218-22.
Title: Constituents of Asparagus officinalis evaluated for inhibitory activity against cyclooxygenase-2.
Authors: Jang DS, Cuendet M, Fong HH, Pezzuto JM, Kinghorn AD. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Abstract Summary: As part of a project directed toward the discovery of new cancer chemopreventive agents from plants, two new natural products, asparagusic acid anti-S-oxide methyl ester (1) and asparagusic acid syn-S-oxide methyl ester (2), a new acetylenic compound, 2-hydroxyasparenyn [3',4'-trans-2-hydroxy-1-methoxy-4-[5-(4-methoxyphenoxy)-3-penten-1-ynyl]-benzene] (3), as well as eleven known compounds, asparenyn (4), asparenyol (5), (+/-)-1-monopalmitin (6), ferulic acid (7), 1,3-O-di-p-coumaroylglycerol (8), 1-O-feruloyl-3-O-p-coumaroylglycerol (9), blumenol C, (+/-)-epipinoresinol, linoleic acid, 1,3-O-diferuloylglycerol, and 1,2-O-diferuloylglycerol, were isolated from an ethyl acetate-soluble fraction of the methanol extract of the aerial parts of Asparagus officinalis (Asparagus), using a bioassay based on the inhibition of cyclooxygenase-2 to monitor chromatographic fractionation. The structures of compounds 1-3 were elucidated by 1D- and 2D-NMR experiments ((1)H NMR, (13)C NMR, DEPT, COSY, HMQC, HMBC and NOESY). All the isolates were evaluated for their inhibitory effects against both cyclooxygenase-1 and -2, with the most active compound being linoleic acid.
3. Journal: J Ethnopharmacol. 2004 Jan;90(1):49-55.
Title: Immunoprotection by botanical drugs in cancer chemotherapy.
Authors: Diwanay S, Chitre D, Patwardhan
Abstract Summary: Asparagus racemosus (Willd.) exhibited various immunopharmacological activities in cyclophosphamide (CP)-treated mouse ascitic sarcoma. Treatment of ascitic sarcoma-bearing mice with a formulation of total extracts of Withania somnifera and Tinospora cordifolia (80:20) and alkaloid-free polar fraction of Withania somnifera resulted in protection towards CP-induced myelo- and immunoprotection as evident by significant increase in white cell counts and hemagglutinating and hemolytic antibody titers. Treatment with these candidate drugs will be important in development of supportive treatment with cancer chemotherapy.
4. Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 May;19(5):296-8.
Title: [Experimental study on apoptosis induced by ursolic acid isolated from asparagus in HL-60 cells]
Authors: Huang J, Sun Y, Lu S.
Abstract Summary: To study the inhibitory effect of ursolic acid isolated from Asparagus on the proliferation of HL-60 cells. METHODS: Effects of ursolic acid on the growth and apoptosis were evaluated by MTT assay, DNA gel electrophoresis and morphology observation respectively. RESULTS: The IC50 value of ursolic acid for HL-60 cells was found to be 8.26 mumol/L and 10-50 mumol/L of ursolic acid could induce apoptosis of HL-60 cells expressed to ursolic acid for 1 day. CONCLUSION: Ursolic acid can markedly inhibit HL-60 cells as well as induction of cells apoptosis
5. Journal: J Ethnopharmacol. 2000 Nov;73(1-2):137-43.
Title: Inhibition of tumor necrosis factor-alpha-induced apoptosis by Asparagus cochinchinensis in Hep G2 cells.
Authors: Koo HN, Jeong HJ, Choi JY, Choi SD, Choi TJ, Cheon YS, Kim KS, Kang BK, Park ST, Chang CH, Kim CH, Lee YM, Kim HM, An NH, Kim JJ.
Abstract Summary: A human hepatoma cell line, Hep G2 cells, is a reliable system for the study of alcohol-induced hepatotoxicity. In this study, we investigated the effect of an aqueous extract of Asparagus cochinchinensis(MERRIL) (Liliaceae) roots (ACAE) on ethanol (EtOH)-induced cytotoxicity in Hep G2 cells. ACAE (1-100 microg/ml) dose-dependently inhibited the EtOH-induced tumor necrosis factor-alpha (TNF-alpha) secretion. ACAE (1-100 microg/ml) also inhibited the EtOH and TNF-alpha-induced cytotoxicity. Furthermore, we found that ACAE inhibited the TNF-alpha-induced apoptosis of Hep G2 cells. These results suggest that ACAE may prevent the EtOH-induced cytotoxicity through inhibition of the apoptosis of Hep G2 cells.
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I wrote to Tervis to inquire if their tumblers contain bisphenol A. They responded with a pdf file, which I can't seem to copy and paste. Basically, the answer is yes, the tumblers contain BPA, and the bulk of the pdf file was citing reasons why I should believe BPA is safe. They claim BPA has a 50-year safety track record and is made in compliance with 21 CFR 177.1580.
I am seriously bummed to learn these tumblers have BPA. I've greatly reduced my consumption of disposable beverage containers by having my tumbler with me every time I leave the house. Also, these tumblers don't sweat, which is a huge bonus during the blistering hot summers here.
Living a simple lifestyle can sure be a challenge.
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Good thread.. before chemo.. i was on very little sugar, no dairy and gluten free. On chemo. oh my. sugar is such a crave!! I am grateful that so far.. appetite is good and am still eating pretty ok. salads, flax seed (1/4tsp), broccoli and good veggies steamed. chicken and meat... usally did not eat as much red meat until treatments started!!! BUT. the fact is before cancer and the change above, lost closed to 20 pounds and did alot of good detoxing liver and system as needed.
I am still able to do yoga and walk. IT is two-sixth day after chemo where i crash. BUT the appetite for sweets is big and do it but with boundaries. I am also with anemia since I lost alot of blood and had transfusions in surgery.Like STaceyR says.. keeping up with excrcise for me works for the pre treatment time.. which for me is Yoga and Pilates... Love the comments and help here!
I am taking my calcium, vit D and b complex and probiotics daily. Keeping my system goin has always been an issue and being on iron is not always easy to mangage.
Sooooo. can chemo just be a period where the taste of what you want is ok as i am craving the bad and try not to overdo!!!Fruits are being consumed daily also. IT is the chocolate covered pretzels and snicky snacks that i am measuring.
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DrJack-That study sounds interesting, but could you summarize it for us mere mortals? I did study basic anatomy and physiology, but I am still lost with all the techno speak. Also, does it explain why eating Asparagus makes your urine smell really bad? LOL
PS, I started growing my own asparagus two years ago. I now have my first crop of 1 stalk! Whoopee! Fortunately, I am the only one around here who likes it, so I will savor it, and then hold my nose when visiting the potty! Hopefully, the crop with be bigger next year!
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Wow!!! I just spent two hours reading this entire topic site! So great! I have learned so much. Real quick....I was diagnosed stage 2, grade 2 IDC in October. Had a double Pmx in December. Just did my "exchange" April 10 and feel great. I need to lose about 40 lbs...I think that is one of the reasons why my 99% estrogen positive cancer came about. I bet changing my diet will help. I have learned so much on the website....thinking about iodine, grapeseed oil and green tea. I do take the supplements (selenium, fish oil, CoQ, garlic, D, multi, calcium, probiotics) but my question is, does anyone have an opinion about WHEN to take them. I sort of slam them all when I go to bed and wonder if that is the optimum time, or if I should be taking them some other time. I don't like the fish oil in the morning as it makes me erpy (word?) and I have been on Tamoxifen for 4 months (no side effects at all) and take it at night to avoid the hot flashes.
Thanks for your feedback!
GG
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Thanks for the info on the plastic - I had it all wrong! Best to get away from all plastic I guess.
Donna - I too have always had a problem with keeping my digestive system running as it should. Throw in chemo and/or iron supplements, and things got real bad. I found this supplement called O3 Right that has really helped me as nothing else ever has. It supposedly works by oxygenating your colon. I order it from gethealthyagain.com.
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Thanks Munchy...good to know. I have been using Fiber Smart and Cleanse More by Renew Life and it works. AFTER Chemo, i will do some liver detoxing also thru Renew Life. That oxgenationing colon sounds good!! Before my cancer dx, when adrenals were very bad etc.. went thru a saliva testing process and a specific kinds of testing and having a Leaky GUT was a issue and for some reason, my food was not absorbing properly and had alot of enzymes to take and reroute the digestive system!!! I often now wonder if some of this stressed my system enough for my bc to really kick in?!
Vivre,, love asparagus!! My DH loves them as much and had a good amount last night!!!Good idea to add to the garden this year. Have to have the green beans in for sure as my GOLDEN loves them!!!
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Althea, I have Britta's glass jug and love it. Of course the water still has to pass through a plastic filter but I have not found a way to avoid that yet. At least once it passes through it, it does not sit in plastic. I try and avoid plastic as much as I can (but still draw the line at filtering, boiling and bottling water in glass bottles as recommended by J. Plant as that seems as too much effort).
Anomdenet, thank you for the info on kelp. I started taking it on recommendation from Jane Plant's book. The pills I bought are produced from kelp from shores of Northern Norway which is meant to be less polluted (I hope). I will look up iodoral once I finish the bottle.
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Hi Amberyba... I'm one of your natural girls!!! IDC stage 2 grade 1 ER/PR + Her2 -... Had my lumpectomy last week with sintinal removed (that was fun)... Refusing rads, chemo, and hormone therapy. I am starting on Protocel next week and I am Very excited about it. You need to get a couple books: The breast stays put and Outsmart your cancer.... They both have websites that are very informative and uplifting. Let's keep in touch. Kim
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Althea I like the idea of the glass pitcher. I am checking into that tomorrow. Also did you work up to 50 mg. of iodine slowly? I was getting some headaches and just tonight I felt a little too revved up. I am breaking one 12.5 pill and taking half in the morning half at about 2 or 3 o'clock.
Lisa thanks for the wellness letter website, I need to read about phytoestrogens. Again like soy 5 years ago, some doctors said ok some said no. I am getting the same story about flax seed again. I eat about a tablespoon or less of sprouted flax with cranberries and goji on my steel cut oats every morning, can't forget the fruit du jour and golden walnuts too! Yum, can't wait for the morning!
Have a great evening everyone, and welcome lemons.
namaste
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Thanks Lisa! Dr Christine Horner is the one who wrote the book I am reading (Waking the Warrior Goddess)...
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I worked up to 50mg of iodoral quickly. I took just one 12.5mg pill the first day, and then increased by one each day until I reached 5, which equals 50 mg. I think I might've had a twitchy eyelid for a day.
I was reading the iodine yahoo group just tonight where someone said flaxseed is goitrogenic. That's the first time I've ever heard that, and I've been eating it for breakfast nearly 2 years now. At the time, relief from fatigue was one of the many benefits listed for eating flaxseed (was reading Christiane Northrup's book on menopause at the time). I still suffer from fatigue, but I don't think it's from flaxseed interfereing with my iodine uptake.
Now that I think about it, I've been steering clear of juicing the cruciferous veggies for about a month now. No improvement in my fatigue and I miss the cruciferous veggies. Especially spinach. And collards and kale through the juicer were some of my favorite greens.
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Vivre, LOL....
Actually, have you tried juicing asparahus with a sclice of apple? It's quite tasty.
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Vivre ??? Your question answered - lol!
Why eating asparagus causes one's urine to have a strong, unique odor
Sulfur-containing amino acids in asparagus break down during digestion, creating an odor when urine is excreted. "It's the same sulfur group that makes skunks smell," said Barbara Hodges, a dietitian with Boston University's nutrition clinic, the Evans Nutrition Group (Hodges cited in Boston.com, 1994).
However, not everyone has the urine odor or perhaps not everyone can smell it. "There's something of a dispute," said Dr. David Stollar, chairman of biochemistry at Tufts University Medical School (Stollar cited in Boston.com, 1994). Some scientists think only half of the population can break down the sulfurous amino acids into their smellier components. Other scientists think that asparagus is digested the same by everyone, but that only half can smell the odor.
The unusual urine smell is nothing to worry about because "the syndrome does not have any pathological significance" (Dictionary of Medical Syndromes cited in boston.com, 1994).0 -
What is the taking of iodine do?
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<</strong> http://breastcancerchoices.org/iodine
Iodine and Breast Cancer
For breast patients, iodine's therapeutic mechanisms of action may be at least three-pronged: Hormonal (11), Biochemical (12-18), Genetic (19).
That is, iodine desensitizes the estrogen receptors, alters the chemical pathways
as well effects on the genes, resulting in less cell growth, and causing anti-tumor
effect by causing apoptosis (programmed cell death) of malignant cells.- Iodine-rich seaweed exhibits an anti-cancer effect in rats and in the lab on human
breast cancer cells. Adding seaweed to rats' food delays the onset and number of rat mammary tumors (20,21). And in the lab, mekabu seaweed plant induced cell death in three kinds of human breast cancer cells. Mekabu had a stronger effect on the cells than the chemo drug, 5-fluorouracil (22).
- Adding iodine to chemically-induced (DMBA) rat breast tumors stops the
growth of the tumors. Adding iodine plus medroxyprogesterone gave the
highestlevel of response: the growth-suppressed tumors showed 100% times
the iodine content than the full blown (nonsuppressed) tumors. The researchers
suggest that the uptake of iodine was enhanced by medroxyprogesterone. (23).
As David Brownstein, MD, phrased it, "You cannot give breast cancer to rats that
have sufficient iodine." - In small, preliminary patient studies, using the screening iodine-loading test,
breast cancer patients excreted less urinary iodine than healthy people, implying
iodine-deficiency (24,25)
Accumulating data has inspired several prominent researchers to call for the
immediate study of iodine as an adjuvant therapy for breast cancer (comparable
to the current use of Tamoxifen or Arimidex).
0 - Iodine-rich seaweed exhibits an anti-cancer effect in rats and in the lab on human
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Lucky...sounds like we have similar breakfasts! LOL
Allie...I bought Waking The Warrior Goddess last September when I was diagnosed...it's on my desk and I use it as a guide! Be sure to check out Dr. Horner's website.... http://www.drchristinehorner.com/
You can read about the relationship between iodine deficiency and breast cancer here
http://www.breastcancerchoices.org/iodineindex.html
http://www.drbrownstein.com/singleproduct.asp?id=787
http://www.femail.com.au/breast_cancer_iodine_thyroid_connection.htm
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Great info on iodine overvview. Does it still apply to those with triple negative cancer since tamoxifen or herceptin is not taken and does it matter if you had a bilateral mx,since there are no mamm. glands left? Had a medical counselor suggest to dab some iodine on my skin and see if it is absorbed withitn 12 hrs and if so, you need iodine. Thanks for the info!
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ngcm05, I have the same question as you.
How do you all space out your vitamins and supplements? I know I need to take my calcium at different times, so I take a multi at breakfast, and then another calcium at lunch and one at dinnertime. I take other things sort of spread around these three times also, but I do take a lot of stuff in the AM.
Hey, ladies, those of you on Iordoral. Dr. Flechas said I needed to take mine with 2 ATP co-Factor pills. Do any of you also do the ATP Co-Factor? Dr. Flechas said "2 pills" but the ATP co-factor bottle says one pill with Iordoral. Just wondering what you all do? I need to email them to find out exactly how much Vit B2 and B3 they suggest...
Spring.
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OMG, what a great thread! I haven't been to these boards for months, but I'm glad I stopped in today and found you all. Some quick breathless questions: is the plastic in the Brita Pitcher considered safe? I have one. How much iodine should one supplement with? Is eating seaween enough, or is a supplement the way to go? Do you all take vitamin D3, and if so, how much?
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Calypso, what is that in your avitar pic? I see hair, but of course, I am totally preocupied with hair these days! lol.
- I use a Briti Pitcher too, I hope it's safe!
- I supplement with 50mg of Iodoral (I did the test at BC choices.org)
- I heard sea weed or kelp may not be as safe?
- I take about 5000 Vit D. per day. I get tested. I am finally up in the mid ranges! yay!
Spring.
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I was reading that healthy adults can take 150 micrograms a day and others with health issues (assume that is us) can take more but it doesn't say how much. It does say one and a half teaspoons of seaweed is 225 micrograms--so it looks like not much is needed?
Also--what brand of multi-vitamin are you all taking? The first ingredient in the one I have now is soybean oil....so I assume I need another kind.
One more thing--if anyone is on tamoxifen, are you limiting your vitamin D so as not to interact with it?
Thanks! Have a great day everyone!
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Spring, I like to think my avatar pic is a goddess of spinning, at least that's why I picked it. She does have hair, I suppose, but who really needs it??
I will do the iodoral test pronto, as well. Don't suppose my regular doc would have the sense to test for it?
I am currently taking 12,000 IUs of D3, until I can get my levels up. Still only 35.1 6 weeks ago.
And I eat dried kelp root from Japan, my mother-in-law sends it to me, as its a big deal in Japan.
Not taking tamoxifen, much to my first onc's horror.
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If I remember correctly- the concern with plastics is the stuff they use to make then soft, bendy and pilable. The harder plastics are less of a concern. I will try to find the write up I read that in. Thinking Brita is ok, esp since water (at least in my house) doesn't stay in too long!
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Has anyone else discovered quinoa yet? It is supposed to be a near perfect protien. I love it
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We love quinoa.....eat it all the time!!!!!!!!!!
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I like Quinao too, need to eat it more. Perfect protein with beans or alone, Marilee? do you know?
I take Tamox. and had not heard, AllieM, that it "interacts" w/Vitamin D. ONC did not mention this. Just said can't take certain class of anti-depresants, that I don't take anyway... Let me know where you heard this? (always something!! aaahhhck!!)
Spring.
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Quinoa is perfect protein by itself!
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WOW..you ladies...I can not keep up!!! Ok..I'm interested in this iodine thing.
where do I get it and how much to take daily?
I have been eating quinoa and have now got my former salami.. white bread eating.. husband eating it!
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lexislove...I have my family loving it too! You can make it for breakfast, dinner or dessert!
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