Breaking Research News from Breastcancer.org
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Women Without Prescription Drug Coverage Less Likely to Start Hormonal Therapy
November 24, 2015
A study has found that women diagnosed with early-stage, hormone-receptor-positive breast cancer with no prescription drug coverage were less likely to start hormonal therapy than women who had insurance coverage for prescription drugs. Read more...0 -
This isn't the correct summary
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Herceptin Plus Tykerb After Surgery No Better Than Herceptin Alone for Early-Stage, HER2-Positive Disease
November 28, 2015
Women diagnosed with early-stage, HER2-positive breast cancer treated with both Herceptin and Tykerb after surgery had the same disease-free survival as women treated with only Herceptin after surgery. Read more...0 -
Completely Removing Anaplastic Large-Cell Lymphoma Is Best Treatment
December 3, 2015
The most effective treatment for implant-associated ALCL is surgically removing the implant and surrounding tissue capsule. Read more...0 -
False-Positive Mammogram Results May Be Linked to Higher Risk Later in Life
December 4, 2015
A large study suggests that women with false-positive mammogram results have a slightly higher risk of developing invasive breast cancer within the next 10 years. Read more...0 -
Triple-Negative Disease May Have New Treatment Option
December 10, 2015
Two studies presented at the 2015 San Antonio Breast Cancer Symposium suggest that adding carboplatin to the standard neoadjuvant chemotherapy regimen may improve outcomes for women diagnosed with triple-negative disease. Read more...0 -
Prolia Reduces Recurrence Risk of Hormone-Receptor-Positive Disease in Women Taking Aromatase Inhibitors
December 10, 2015
A study has found that Prolia improved disease-free survival for postmenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer taking an aromatase inhibitor. Read more...0 -
Lumpectomy Plus Radiation May Offer Survival Benefits for Early-Stage Disease
December 10, 2015
Another study suggests that lumpectomy plus radiation may offer survival benefits for some women diagnosed with early-stage disease. Read more...0 -
Study Suggests Premenopausal Women With Certain Type of Breast Cancer Don't Benefit From Chemotherapy
December 10, 2015
Research suggests that premenopausal women diagnosed with luminal A breast cancer have the same disease-free survival rates whether or not they receive chemotherapy after surgery. Read more...0 -
Arimidex or Tamoxifen Reduce Recurrence Risk After DCIS Equally Well in Postmenopausal Women, Choice Depends on Age, Side Effects
December 12, 2015
Two studies presented at the 2015 San Antonio Breast Cancer Symposium looked at the effectiveness and side effects of Arimidex and tamoxifen to reduce recurrence risk after DCIS surgery and radiation in postmenopausal women. The studies found that the medicines reduced the risk of recurrence about the same amount, but there were differences in side effects. Read more...Marisa Weiss, M.D., Breastcancer.org chief medical officer and founder, talks about these studies in this Facebook video.
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Kadcyla Improves Survival in Women Diagnosed With Metastatic, HER2-Positive Disease That's Stopped Responding to Herceptin and Tykerb
December 14, 2015
The TH3RESA study found that Kadcyla improved overall survival in women diagnosed with metastatic, HER2-positive breast cancer that had stopped responding to Herceptin and Tykerb compared to the women's doctors' treatment of choice. Read more...0 -
New Guidelines Address Breast Cancer Survivors' Long-Term Needs
December 15, 2015
The American Cancer Society and the American Society of Clinical Oncology have developed new guidelines on breast cancer survivorship care. Read more...0 -
Podcast:
Research Highlights From the 2015 San Antonio Breast Cancer Symposium, December 14, 2015
In this Breastcancer.org podcast, Brian Wojciechowski, M.D., Breastcancer.org's medical adviser, talks about four studies that were presented at the 2015 San Antonio Breast Cancer Symposium, December 8-12, including studies that offer encouraging news about treatment for women diagnosed with triple-negative disease and metastatic, HER2-positive breast cancer. Listen to the podcast to hear Dr. Wojciechowski explain:
- what luminal A breast cancer is and why women diagnosed with this subtype didn't seem to benefit from chemotherapy after surgery
- why adding carboplatin to a standard chemotherapy before surgery for triple-negative breast cancer improved pathologic complete response rates and what this means for women with triple-negative disease
- why postmenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer who are taking an aromatase inhibitor and have experienced bone loss might want to consider taking the targeted therapy denosumab
- results showing that Kadcyla improves overall survival in women diagnosed with metastatic, HER2-positive breast cancer that has stopped responding to Herceptin and Tykerb
Running time: 18:51
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Blog:
Breastcancer.org Covers the 2015 San Antonio Breast Cancer Symposium, December 14, 2015
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FDA Approves Marketing of DigniCap in United States
December 18, 2015
On December 8, 2015, the FDA approved the marketing of the DigniCap Scalp Cooling System in the United States. Read more...0 -
Treating Residual Disease With Xeloda Improves Survival in Women With Early-Stage, HER2-Negative Disease
December 22, 2015
Women diagnosed with early-stage, HER2-negative breast cancer with residual disease who were treated with Xeloda after surgery had better survival compared to women who didn't get chemotherapy after surgery. Read more...0 -
Cancer My Story..... you might see this on a few discussion boards about ACLC because of my situation and the unknowns around all of it including the UNKNOWN if that is what I have but maybe someone else will chime in and explain anything they know,,,,, knowledge is power, right?
Somewhat a long complicated story, that was suppose to be a simple diagnoses of early detection through Mammo & Sonogram. Mammo always came back suspicious so they started to include it with a sonogram. In July 2013 DCIS was reported. Aug 2013 Bilateral Mastectomy with reconstruction with expanders, Dec 2013 implants put in. Cancer still seen in pathology behind left nipple, finally gave in Dec 2014 and had it removed and some revision on reconstruction. Waited the year for things to settle into position to see what revision might be needed before reconstruction and trying to decide about gambling the re-occurrence of the breast cancer because my Doctors opinion was the odds of cancer reoccurring that was seen behind the nipple was very low, 1% maybe. I don't gamble with money so why am I going to risk losing a bet that I had already lost with even getting DCIS.
After nipple removed I was going to take 2015 off and no surgeries. Replace nipple in 2016 but Capsular Contracture aka CC started in both breast. June 2015 continue to get worse in the left breast by Sept 2015 I had to have emergency surgery and have the implant removed because it was so badly infected. Infection was draining from the incision site and breast was red. The treatment plan was to let it clear up for 6 months and then put in the horrible and dreaded expanders, approx. 3 months after that then remove the right implant and clean up CC and put in 2 new implants. Start from scratch.
Here it is 3 months later Dec 2015 I had to request an MRI of both breast because of lumps I felt and doctor reluctantly agreed, those results came back that I need further testing on left breast area where I have NOTHING to see if cancer has returned. While waiting on that test the right breast is now infected. Saw it coming on with the redness, had labs for scheduled upcoming ONC appt WBC was on the higher side, went to PS and he put me on the antibiotics but not seeing any improvement. Actually, causing other female discomfort that normally goes along with using antibiotics that I felt after taking the 1st pill. Appt for ONC is day afer U/S - Biopsy.
Tomorrow I go for Ultrasound with Biopsy on both sides now that right one is infected otherwise it would have only been the left side. Doing some of my own research because I KNOW Doctors do not have all of the answers but if anything I can help provide them with information I find in the research I do than I have to help my own cause. There are so many unknowns and then I find this link http://center4research.org/medical-care-for-adults/breast-implants-and-other-cosmetic-procedures/breast-implants-and-cancer-of-the-immune-system/
Starting with a Google search of "Does Capsular Contracture cause" and was going to ask infection but saw the word cancer so I clicked on it. The following is from that link which includes the following along with other info….
Most women were diagnosed with implant-associated ALCL by testing the fluid that collects around the implant, called a seroma.4 Seroma is a potential complication of breast implants and is usually not caused by ALCL. It is important to note that even when ALCL is in the breast, it is not breast cancer, but rather a cancer of the immune system. Most breast implant-associated ALCL are called "effusions", because the cancer cells are within the fluid which has collected inside the scar capsule. Women with ALCL in the scar tissue surrounding the breast can be treated by removing the implant and the surrounding scar tissue. This surgery is known as a capsulectomy.
Although there have been few studies of ALCL among women with breast implants, one clinical follow-up of nine women who had a capsulectomy after being diagnosed with breast implant-associated ALCL found that all nine were healthy and disease free when they were studied 3.5 years later, and no chemotherapy or radiation treatment was necessary.5 However, there have been case studies reported of women with breast implants who went to their doctors because their breasts were swollen, and the doctors found a tumor near the breast implants. These women with tumors had a more aggressive form of ALCL that recurred after a capsulectomy and needed to be treated with chemotherapy or radiation.5 Although earlier studies reported shorter-term results, a recent long-term follow-up of 60 patients with breast implant-associated ALCL showed that the ALCL was more likely to be fatal for women who had a solid ALCL tumor than for women who had ALCL effusions (cancer cells in the surrounding fluid).6 All of the patients with effusion-type ALCL were still alive 5 years after their diagnosis, compared to only 75% of the patients with solid ALCL tumors. The effusion-type ALCL tumors were also less likely to recur after treatment, returning in only 14% of patients, compared to 50% recurrence ofsolid ALCL tumors.6Longer studies with more patients are needed to determine the best treatments for both types of breast implant-associated ALCL.
So far, there are not enough data to show if there is more risk for ALCL among women with silicone gel implants compared to saline implants or for women who get implants for reconstruction rather than augmentation purposes.2Since it is impossible at this time to tell which women are most at risk for ALCL, it is crucial for women with all types of implants to have routine follow-ups. For women with silicone implants, FDA recommends getting a breast coil MRI three years after getting silicone gel implants, and every two years after that.7 Women with saline implants should have regular clinical breast exams by an OB/GYN or other physician.
Implant companies and plastic surgeons have been quick to dismiss the FDA's findings, as they have with most claims about the safety of implants. A statement on ALCL from Allergan, a manufacturer of both silicone and saline breast implants, said, "A woman is more likely to be struck by lightning than to get this condition."8 Four hundred people are injured or killed by lightning every year.9 ALCL may strike fewer women but it is an avoidable risk that most of us would choose to steer clear of, just as we do not go swimming during a thunderstorm. In addition, it is possible that there may be more cases of ALCL than have been reported. It is not standard practice to examine the scar capsule after a woman has had her breast implants removed, and it is possible that among the many women who get their implants removed every year, some have slow-growing ALCL in the scar capsule that they were not aware of.5The FDA is in the process of establishing a registry to monitor the number of breast implant-associated ALCL cases and plans to continue studying the link between breast implants and ALCL. While the risk of ALCL appears to be very small, many women would not want to take the chance of developing cancer as a result of breast implants. In addition, the link between breast implants and autoimmune diseases has been hotly debated for two decades, and the evidence regarding ALCL once again raises questions about the possible impact of breast implants on autoimmune disease or symptoms such as joint pain, body pain, memory loss, and chronic fatigue.
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No surprise that those making the money on the products are quick to dismiss and claim more likely to get hit by lightning….. really???? Like they said you avoid areas that increase any chance of getting struck by lightning. With additional testing maybe they would see more of a connection between ALCL and implants for any reason reconstruction or augmentation. Does this mean I don't want to have reconstruction? No not in the least. I don't want to look like this forever and yes I want to move forward but it might be with a different kind of material. Research and studies are needed and the outcome of my additional test which are still ahead.
Not sure if my situation helps any one else in any way. I really am in shock that "simple" DCIS has continued on to this journey. I know I have dark days but I hide them the best I can behind the smile that I let others see. I don't want to be that person no one wants to be around when you are always depressed. I steer clear of those type of people so I don't want to be one. Yes it is a depressing but the saying is… you have a choice on your attitude…. Maybe not your situation but your attitude you can control. And I know that all of the things going on are in God's hands. So I have to trust He will take care of it.
Does that mean I still don't cry? Absolutely NOT, I cry ALOT.
Do I have days where I am losing my spirit, you Bet I do.
But I still TRY and control what I can which is my attitude. Not easy, never going to say otherwise. But I have the most amazing friends and family so many people that I LOVE and that I really appreciate.
To be continued……
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'Rogue' milk-producing protein helps breast cancer spread
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A fifth of cancer therapy trials fail to enlist enough participants
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FRIDAY, Dec. 11, 2015 (HealthDay News) -- A critical illness can lead to bone loss, a new study finds.
The research included 66 seniors who spent at least 24 hours on a breathing machine in an intensive care unit (ICU). One year after their ICU stay, the patients had 1.6 percent less bone density in their lower spines and 1.2 percent less bone density in their thigh bones than would be expected.
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Timely Breast Cancer Treatment Improves Survival
Dec 28, 2015
Two studies have found that delaying surgery by 30 days and chemotherapy by 90 days can lead to worse survival. Read more...0 -
Postmenopausal Women With Gum Disease Seem to Have Higher Breast Cancer Risk
January 5, 2016
Research suggests that postmenopausal women with gum disease are more likely to develop breast cancer than postmenopausal women who don't have gum disease. If a woman has a history of smoking, the risk of breast cancer may be even higher. Read more...0 -
Being Diagnosed at Younger Age Increases Risk of Cancer in Opposite Breast
January 6, 2016
Research suggests that women with an abnormal BRCA1 or BRCA2 gene who are first diagnosed younger than age 41 have nearly double the contralateral breast cancer risk of similar women diagnosed when they're age 41 to 49. Read more...0 -
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http://www.medpagetoday.com/HematologyOncology/Bre...
Radiologists Remain Scornful of USPSTF Mammo Guideline
But a more favorable reaction from other specialists
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Folks, we appreciate your wanting to share research, but please reserve this thread for Research News stories published by Breastcancer.org. Thank you!
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New Dietary Guidelines Issued, Focus on Dietary Patterns
January 8, 2016
The U.S. government has released new dietary guidelines; reactions from experts are mixed. Read more...0 -
Detection Rates Similar to Mammograms, Ultrasound May Be Option if Mammography Isn't Available
January 9, 2016
Ultrasound seems to be a good alternative for breast cancer screening if mammography isn't available. Read more...0 -
If Chemotherapy Before Surgery Destroys All Breast Cancer in Lymph Nodes, Survival Is Better, Especially for Women With HER2-Positive Disease
January 13, 2016
A study suggests that lymph node pathologic complete response is associated with better survival in women diagnosed with HER2-positive, stage II or stage III breast cancer. Read more...0
