Abemaciclib Verzenio for Stage IV

andy280

Thanks @seeq !

This is amazing information:

A time-dependent covariate analysis was performed to examine the association between current dose level (150, 100, and 50 mg) and PFS. Compared to being treated at the 150 mg dose level, there was no apparent difference in PFS for patients reduced to 100 mg (HR [95% CI]: 0.764 [0.467–1.251]; 

p= 0.2849) or to 50 mg (HR [95% CI]: 0.985 [0.511–1.902]; p= 0.9650)

Why would any doctor prescribe 150 when 100/50 works equally well with less side effects unless there are some other studies that show greater efficacy of 150

https://community.breastcancer.org/en/discussion/comment/5915706#Comment_5915706