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New metastatic diagnosis

meme5 Member Posts: 43

I just received my path report after 4 months of testing for a suspicious lymph node in portahepatic area near liver

Results: porta hepatic lymph node positive for metastatic carcinoma with apocrine features. Tumor cells positive for GATA3 and CK7, negative for PAX8, GCDFP and mammoglobin. Although breast origin is favored GATA3 is not specific for breast primary.

Liver resection: benign hepatic parenchyma with no metastatic carcinoma

Can someone help me understand what all this means and what kind of treatment is ahead. I am 74 and otherwise in really good physical health. I was diagnosed with invasive lobular carcinoma, stage 2B in 2013. I did double mastectomy, 8 rounds of ACT and 5 years of AI.

Now what



  • parakeetsrule
    parakeetsrule Member Posts: 605
    edited October 2022
    Sorry you've found yourself here for this! You may get more responses if you ask this question in the threads specifically for liver mets and/or lobular.

    But the best thing to do is ask your doctor. I'm not a radiologist but it sounds like they aren't 100% sure it's breast cancer?

    What treatment is head depends on a lot of things.
  • cowgal
    cowgal Member Posts: 625
    edited October 2022

    Sorry you find yourself here and hope that you will find this site very helpful and supportive. I agree with parakeets that you can find some help on the threads specific to liver mets. I am not a radiologist either but I think it might mean that they do think it is breast cancer but that they think it may not be related to your original breast cancer. For example, in my case, they were able to determine that my recurrence of cancer in a lymph node and my collarbone was from my original cancer from my 2010 stage 2B diagnosis. Definitely ask you medical oncologist what path they are thinking you will be on.

  • meme5
    meme5 Member Posts: 43
    edited October 2022

    I received an addendum to my path report this morning stating the cancer in lymph node was weakly and partially positive for ER beta1 and negative for androgen receptor. Can someone shed some light on this for meaning? I know it means most likely coming from original breast cancer but what is beta1 and androgen receptor?
    Thanks for any insight.