Digestive side effects from Verzenio
Hi there. I was initially diagnosed with Stage 3a HR+, Her2- breast cancer at the age of 39 (2004). Treatment included a mastectomy with 23 lymphnodes removed (1 positive one), typical AC/T chemo regimen, radiaction, and Tamoxifen for 5 years. I was in remission. Fifteen years later, almost to the day, I started to have trouble breathing. I passed it off to either pneumonia or asthma (neither of which I had ever had), but I was taking care of my mother who was fighting Stage 4 colon cancer and was right then dealing with bleeding from her nipple from her remaining breast (she had had breast cancer and a mastectomy of her right breast at the age of 52), so I didn't have time to deal with me. Once I got her medical issues handled, I saw a doctor and after 3 different doctor visits and 1 chest xray, it was discovered I had a large pleural effusion on my right side which had collapsed my right lung and partially collapsed my left lung and I had fluid around my heart. The oncologist who originally treated me started me on Verzenio 200mg dose along with anastrozole. I had improvement in my breathing and energy level (heart fluid mimicked symptoms of heart failure so I could barely walk around) after being in treatment for about 2 years on it, I have maintained my improvement and have felt pretty good and I have now been on that treatment regimen for about 3 years 10 months. My RBC and WBC count is somewhat low and my immune system has taken a hit so the doctors tell me to watch closely for infection. Here is my question to see if anyone else has experienced this:
In November 2021 one night, my stomach started cramping really bad, as if I was in child labor. The craps continued from about 7pm until about 3am and it included vomiting at about 12am. When they finally subsided and I was able to get some sleep. During the cramping, I took GasX and some Senekot because I had no idea where this pain was coming from. Since that first time, I have had this happen about 3 more times: stomach cramping, vomiting, everything subsiding after about 9 hours. It always has happened at night, starting usually when I'm about to go to bed and the pain continues until early morning, when it finally subsides. I've continued to take Senekot each time in hopes that getting everything out of my stomach and intestines will help, but the pain subsides before the Senekot even accomplishes its goal. This latest time (last Sunday), I also took some Motrin hoping that would alleviate some of the cramping. The following Wednesday, I had a bowel movement that had the "coffee ground" appearance which possibly indicates blood. I've had this a couple of other times as well over the last year, but I didn't pay attention if they coincided with the stomach cramping issue. I have an appointment coming up with the oncologist for a follow-up soon, but wondering if anyone else has had this problem. I'm not really very good about avoiding the foods which are recommended to stay away from (fried foods, raw veggies and fruits, dairy, etc). Could it be I've irritated my stomach and intestines by eating the wrong things while on these meds? After this latest bout, I've been eating really clean and drinking water and I feel good, but just checking if anyone else has experienced this. Sorry for the long post.