Tamoxifen and bleeding
I am 44 years old and premenopausal. I have been taking Tamoxifen for 8 months. I stopped getting my period in December right after starting the Tamoxifen and have not had a period for 8 months, not even spotting. This week I was at work and started what I thought was my period but after a couple hours turned into excessive bleeding like a faucet turned on and passing multiple large clots. I was soaking through a large pad every half an hour. I ended up in the ED a few hours later and was admitted. My hemoglobin dropped 3 points in 24 hours and I had to have a D&C to stop the bleeding and take biopsies. My imaging from my transvaginal ultrasound showed my endometrial lining in my uterus over a year has gone from 7mm to 2.4 cm. This is concerning for endometrial cancer. My biopsies came back benign thankfully. Has anyone had these issues with thickening of the endometrial lining causing severe bleeding from Tamoxifen? They seem to think it is the Tamoxifen and have taken me off of it until this resolves. I will be seeing my gyno and oncologist in a couple weeks but was curious if anyone has had this happen with no period at all for 8 months then severe bleeding?