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Considering TH regimen for HER2+ microinvasive (very early stage) BC

Anyone have feedback who has done Taxol plus Herceptin? I just met with a medical oncologist to discuss possible chemo as I was thought to have DCIS but in fact, at mastectomy, was found to have about 8 foci of microinvasion (defined as < 1mm each).

I was wondering what your experience has been with the TH regimen. The other option we discussed was Kadcyla. Thanks!

Comments

  • lemonwedge
    lemonwedge Member Posts: 14

    Hi, saf1234, did you make a decision about your treatment?

    I'm in a similar boat and there aren't many of us!

  • snm
    snm Member Posts: 154

    @saf1234 hello! I also would love what your decision was? I was found to have a single focus of invasive 1.3mm along w high grade dcis. It was Her 2+ so I decided BMX but no to radiation (it was on left side and I didn't want to risk my heart).

  • snm
    snm Member Posts: 154

    @lemonwedge Hi there! Hopefully we get some response! What is your situation, if you mind sharing?

  • lemonwedge
    lemonwedge Member Posts: 14

    @snm Hi! Glad to hear from you. My situation was +++ microinvasive (by definition less than 1 mm each) multifocal (2) IDC with DCIS, and it was staged as T1mic, negative nodes. Had a BMX. Radiation was not on the table, but I can take tamoxifen, which will reduce my recurrence risk by not a whole lot. I was not offered any additional treatment. I don't really know how to feel OK with just being monitored yet. I'm thinking about taking the Signatera test just to stay on top of the possibility of recurrence.

  • snm
    snm Member Posts: 154

    @lemonwedge yeah I hear you.. does feel odd to be monitored only.. your tamoxifen decision is a big one given the side effects and tiny cancer. I was not offered the signatura test maybe bc my tumor was hormone negative? Anyway good luck with the decision making!

  • lemonwedge
    lemonwedge Member Posts: 14

    @snm I think doctors don't know what to do with Signatera yet. It can tell you if there is I don't know what you call it—"tumor debris" in your blood, but it doesn't say where it is, so that can cause a lot of panic and confusion. I still think it might be good for me to have that information even if I don't know what it means or how to pursue it. I don't think hormone status has anything to do with the test—they take the tumor and analyze it, making a test that is specific to you.