Did your doctor talk about your Ki67 %
Hello - I have IDC Stage 2 (++-), and I am one week out from my bilateral mastectomy.
My lymph Node pathology reports were posted online, and from what I can read, there is no cancer in my lymph nodes. However, my Ki67% - was reported at 43%. so I have a Ki67: 43%. Is that bad?
Did your doctor put much stock into your Ki67 number? I was just wondering what others have learned about their Ki67 number and how it might have impacted treatment.
Maybe now that I had a BMX it doesn't even matter what my Ki67 score is?
Thank you
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I am still waiting on my bilateral mastectomy, but all the surgeon told me was that I still MAY need chemo because of the high grade and the high Ki-67. But im only stage 1 and doesn’t appear to be in my lymph nodes. My ki67 is 40%. But I wont know for sure of my treatment plan until I see my oncologist for the first time after my surgery. I’ll be interested in knowing how’s your oncologist treats you! I’m so anxious over here. My diagnosis was 2/1 but I still haven’t received a surgery date.
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Hi @nilespark44 and @ebfitzy -
Although KI67 is one indicator of the BC biology, I think it has to be looked at as only one piece. I had a Ki67 of 40% (considered high), but also high ER+, low PR+ and Grade 3. I had no positive lymph nodes and was Stage 1. The best thing to try and determine chemo needs is the Oncotype test. You might want to ask about that soon as it does take a week or 2 to come back. I was really resistant to doing chemo—-just hated the idea. However, my Oncotype test came back high, so really not much choice if I wanted to reduce my odds of recurrence.
Know that if you do end up with chemo, you WILL get through it. It's another club no one wants to join, but you do what you gotta do.
For now, take things one step at a time.
Take care. You'll get through this whatever is your treatment plan!
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mandy23, ebfitzy - thank you both for your responses. I did hear from the doctor's office today, and they confirmed that the cancer has not progressed to my lymph nodes. When I asked about KI67, the nurse said the next step was to get the Oncotype report back and see an oncologist. It will take about 2 weeks to get the report back.
Ebfitzy, I hope you are closer to a surgery date now. I just had my BMX last week, so if I can help answer any questions about the surgery or items I used to help me reover. Let me know!
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I agree, I won't know anything till I see the Oncologist and get the OncoType report. Till then….I wait. I am now getting impatient….as I want to know what all this stuff means that I am reading about.
My diagnosis was 2/11, and I had surgery last week. I had a skin-sparring mastectomy with expanders. So far, the recovery hasn't been bad at all. I've managed the pain with Tylenol and ibuprofen. They did give me something stronger for pain, and I've taken it 2x to help me at night with sleep.
I've been walking a little bit each day since surgery and doing the arm exercises they told me to do, and I swear it helps. Please, if you can, get up and move around after mastectomy. Even if it's walking in your backyard or house, movement helps.
If you have any questions about mastectomy, please let me know. I just went through it. Below are some items that have helped me this week!
Some items that helped me from Amazon:
Chest Pillow from Amazon: MOYOAMA Post Mastectomy Pillow with Cold Pack - Recovery After Breast Cancer Surgery, Breast Augmentation - Lightweight Post Surgery Pillow with 4 Built-in Pockets to Support Healing
I slept in my bed with this from Amazon:
Lunix LX5 4pcs Orthopedic Bed Wedge Pillow Set, Post Surgery Memory Foam for Back, Leg Pain Relief, Sitting Pillow, Adjustable Pillows Acid Reflux and GERD for Sleeping, with Hot Cold Pack, BrownMastectomy Shirt From Amazon: I wore this shirt home from the hospital daily. I have a few. It's not as expensive as some other mastectomy shirts, and it's comfy, and the snap-buttons and inside pockets are excellent. Amazon: RENOVA MEDICAL WEAR Mastectomy Recovery Shirt with Drain Pockets
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Sept. 2022-Left breast. 1A, or stage 2, ER 100%, PR 70%,HR-2 Neg. (score +1), Ki-67 8%, 2 lymph nodes positive with cancer. They did not offer a mastectomy since it had entered my nodes. Anastrozole for 5 years, max radiation to left breast. DNA test -14%. So they say , I have a 85% chance to live 10 more years. Average for my diagnosis is 41 Months.
Anasrozole has hit me hard. Weak, bone and joint pain, eating issues, weight down 10 pounds, night sweats and hot flashes, mood swings and sleep disruption. I am half the person I was , anger and frustration became the norm. Searching for hours on line to understand what was happening
Nurse said I should not be having so much trouble with adjusting to Anastrozole and there must be something else was wrong. Spent time going to my GP looking for answers. nothing came out of that.
Worked with a dietitian and have seen some improvement.
Currently my left eye has been swollen for weeks, pressure and shots of pain radiating down nose and up head. Tried antibiotics for 10 days with no change. That was 2 weeks ago. They said to wait and see if things got better . Returning to GP this am, possibly more antibiotics.
My situation is also compromised because I can not have a MRI which is recommended to find new cancers that might develop. I have 13 screws and a metal plate in my left arm that reacted during a MRI and caused nerve damage on my entire left side of my body.
Water Fitness has helped more than anything for body pain. Spend 2 days a week for 1hour in a therapy pool working muscles and joints. Always feel better after that .
Thanks for listening and I hope things get better for you.
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Hi @artwish -
Wow. Really sorry to hear that all this is happening to you. 😒
Have you talked to your MO about switching to a different AI? There are 3 of them and some people have don't have as bad reactions to one or another. They are Anastrozole (Arimidex), Exemestane (Aromasin), and Letrozole (Femara). It seems like if this all started after the Anastrozole, it would be worth trying a different one? Are you able to see the MO if the the onc nurse isn't helping? Or is there a different nurse or MO that you could see to hope they will have a different perspective? If the oncology department isn't responding to your concerns, maybe your GP could help you find a different onc group?
Sometimes you do need to advocate for yourself….unfair as it is. One would hope they would listen to your concerns. Good to hear that at least water fitness is helping. By all means keep doing that.
Hang in there and I hope you find some relief soon.
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I _ agree with Mandy23; please talk to your medical oncologist about all this. Advocate for yourself. This is not the way you should feel. I am thinking of you and hoping your days are getting better. Please respond if you need more advice or want to vent.
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Thank you, Might have put too much of the negative in my first post. Things are better than a year ago mostly due to water fitness. Last Spring, I tried Tie Chi & Yoga, but my left arm would hurt too much. Took a class called Water Walking and my arm felt better right away. It is also helping to keep my fast developing arthritis from getting worse. A good friend who is suffering from the side affects of chemo works out with me. We are both doing better. As for changing meds. not going to happen. Chemo is the other choice with no better out come. My research says this is the best choice foe my age, 72. I was very active kayaking, gardening and dancing, Not to mention caring 50# boxes of clay for my work. I just miss my old self ,but the new self is getting better.
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