Fill Out Your Profile to share more about you. Learn more...

tnbc mutated to hormone positive?


Has anyone had their tnbc mutate to be hormone positive? I was originally 99% er+ and 1% pr+. Then I was tn. Now I'm 95% er+ and 75% pr+! My understanding is that breast cancer usually becomes less hormone positive, not more…I'm not sure what to think…


  • exbrnxgrl
    exbrnxgrl Member Posts: 5,060


    I have no medical training or expertise beyond being a stage IV patient for over 12 years. I know that there are “typical” occurrences, paths to progression, etc., but what I have learned over that time is that are also many atypical situations. Breast cancer is far more complicated than I could have ever imagined. Just because something might be usual doesn’t mean the unusual doesn’t happen sometimes. My whole bc experience has been unusual. Take care