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Waiting for Onco test result…..


Had lumpsectomy and now waiting for onco test score to determine if I need chemo or not. Oncologist doesn’t think so based on my other data - eg Stage 1A 1.5cm tumor size . Grade 2

Can anyone tell me what the ER and PR mean below especially the 3+ want to work out my H score ?

Pathologic TNM Staging (AJCC 8th edition) pT1c pNO (i+) (sn)

ERA (IPOX) Positive (3+ in 91-100%), per case SUS-24-2020

PRA (IPOX) Positive (3+ in 91-100%), per case SUS-24-2020

HER-2/neu (IC) Negative (0, scale 0- 3+), per case


HER-2/neu (FISH) Negative, per case SUS-24-2020


  • exbrnxgrl
    exbrnxgrl Member Posts: 5,072

    No clue as I’m not a doctor nor have any medical training. By your “H score” do you mean HER2 neu? Clearly that was negative 😊 . Have you called your doctors office to ask those questions? Because of my lack of medical training, I am not comfortable interpreting medical reports (though having been stage IV for over a decade, I am more familiar with medical terms than I want…) but we do have members who don’t have my cautious attitude and will likely be along soon.

    I’m sorry you were dx’ed. Take care

  • maggie15
    maggie15 Member Posts: 1,081

    As exbrnxgrl said most of us are not doctors. The path report shows your tumor is highly positive for estrogen and progesterone receptors (3+, present in over 90% of cells) and negative for HER2 (score of 0.) HER2 scores of 3 are positive while scores of 1 are HER2 low and those of 2 are either low or positive depending on the result of the FISH test which must be done. The H score, if used, is calculated by a pathologist by hand or using a digital image analysis since it uses the visual IHC staining on the slides. I don't think that it would tell you anything you don't already know but you can ask your doctor about what your particular pathology lab does. Hopefully your oncotype score will be favorable but whatever the outcome you will get through your treatment. I hope things go well for you.

  • sosa98
    sosa98 Member Posts: 7

    thanks both for your thoughts and you are both heroes!

    Will ask Dr Monday but it was the 3+ in my PR and ER that I didn’t understand and was curious if anyone knew.

  • moderators
    moderators Posts: 8,287

    Hi @sosa98,

    You can read all about what the hormone receptor status means here:

    And more info about what each piece of your pathology report means here:

    We hope this helps! Let us know if there's anything else we can do to help.

    —The Mods