Lupron, Tamoxifen and Oncotype
Hello All,
I had Stage 2A grade 3 DCIS & IDCIS Cancer. Im 42 and a Mas w/DEIP. My oncotype number was 19 with a 6% chance of recurrence however my oncologist used a tool call Exact Science RSClin tool that says given how big my tumors were (biggest tumor was 28mm) and high grade that my recurrence rate is 17% with only taking tamoxifen. Chemo would’ve only brought it down by 1-3% so my MO thought it would be best to take Lupron shots until menopause and then switch me to AI. I see other posts with women who recurrence numbers were lower than mine but prognosis were a bit worst. I have not decided on the Lupron shot as yet and haven’t spoke to my MO re it bc Im not a fan of hers. I’ve been on TMX for almost 3 weeks and I havent experience any SE…yet. I take it with a multi vitamin everyday and pray over it. I guess my question is, am I at high risk waiting to take Lupron until I feel comfortable with the idea of it? I don’t want to take Lupron and it messes up my no SE I’m having. Have any of your MO spoken to you re your recurrence #s based on the RSClin tool? I know ASCO was earlier this month, any news on new ways to suppress ovaries?
Comments
-
I can't answer your question directly but I am on monthly Zoladex injections plus tamoxifen and have very little in the way of side effects. I think chemo plunged me into menopause anyway so the odd hot flush I get I would put down to that. Are you still having periods?
0 -
Hi! Yes I still have my period.
0 -
I would consider the injections carefully then anekasan238. You probably don't have much to lose by trying them for a few months. I feel better as a menopausal woman than I did when I struggled with PMT and horrible heavy periods. I don't think I'm that unusual. It would be a different conversation if you have a pile of side effects. There is certainly evidence it increases the percentage survival in our situation (the SOFT trial from memory). Good luck with whatever you decide.
0 -
Hi @anekasan238,
We're just checking in to see how you're doing — have you talked to your MO yet about all of this? We're curious to hear the outcome and how you choose to move forward.
Also, here's some info on the SOFT trial that @starbridge mentioned:
Keep us all posted!
—The Mods
0
