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Tamoxifen side effects

Hi, I am a 69 year old diagnosed with Stage1 HER 2 + ductal carcinoma 4 years ago. Ive been taking Tamoxifen for 3 years post lumpectomy for removal of a lump less than 1 cm. Lymph node testing was negative. I completed Radiation, but no chemo was recommended. Genetic testing negative and no family history. I have Osteopenia that is stable since Parathyroidectomy 7 years ago to remove two benign tumors. Two of my 4 parathyroid glands were removed. In the past year I've developed joint pain and fatigue. Last month after having the combined Flu and Covid vaccines I developed severe chills and joint stiffness that kept me on the couch taking Ibuprofen and Tylenol for two days. Now, a month later, the joint pain and chills are still present and magnified after doing even light exercise. The exercise feels good at the time; swimming slowly 30 min, or rowing machine 20 min, or stationary bicycle 30 min. When I have lifted weights it is a light workout, careful not to fatigue my muscles followed by stretching. Joint ache and chills set in a few hours after exercise. I lie down for several hours after exercise when I can, and take Tylenol and Ibuprofen on days it is worse. I have discussed these issues with my Oncologist who recommends staying on the Tamoxifen. I am interested to hear your take on this addressing risk vs. benefits. I am not a candidate for Aromatase Inhibitors due to removal of two Parathyroid Glands.

Comments

  • moderators
    moderators Posts: 9,944
    edited December 2025

    Hi @brewerg, welcome to Breastcancer.org! We’re hate that you’re dealing with these symptoms, but we’re glad you reached out. We're sorry you still didn't get other members responses. While you’re waiting, here are a couple of resources from our main site that you might find helpful:

    https://www.breastcancer.org/treatment/hormonal-therapy/tamoxifen

    https://www.breastcancer.org/treatment-side-effects/pain/bone-joint

    In addition, many of our members report that taking Claritin helps with bone and joint pain, as some breast cancer treatments stimulate the immune system to help the body make more neutrophils, a type of white blood cell. This process also creates histamines, which may cause bone pain. So, Claritin, an antihistamine may ease the symptoms you're experiencing.

    We hope this helps. You’re not alone in this, and support is here. Please let us know how you’re doing or if you learn more after talking with your oncologist again.

    Best,

    The Mods

  • hi, have you considered/discussed with your doc, that you might still be having aftereffects from covid?> sorry you're going through this and hope it gets better soon!