Breaking Research News from sources other than Breastcancer.org

claireinaz · July 2018

Ah, I get it now. Arizona has no such warning, but I do know about the hazards of paper receipts from stores (grocery etc) and wash my hands to remove the chems that can cause cancer from those receipts. Whole Foods, I know, uses paper that is safe, but others don't.

Claire

aterry · July 2018

Marijen & Claireinaz, the warning exists on products all over the country. I live in NYC. I call it the California warning because it relates to legislation passed in that state and because the warning specifically says, "...known to the state of California to cause cancer and/or birth defects...." The guy at the hardware store said to me, "You don't have to worry about it since this isn't California." I said, "Do you think cancer knows what state you live in?" A neighbor found the warning on a portfolio that she bought for her art work. I think it's widespread.

And, yes, the products I saw were made in China but I don't know whether manufacturers in the US have eliminated those chemicals from their supply chain.

marijen · July 2018

aterry, great answer. What did the hardware guy say to that

Chemokaze · July 2018

Oncolytics: Significant Pipeline Value In The Fastest Growing Area Of Oncology

http://flip.it/IeTS-A

marijen · July 2018

Who are 'You People' Anyway? – National Pain Report

http://nationalpainreport.com/who-are-you-people-a...

marijen · July 2018

APPROVED FOR TREATMENT AFTER SURGERY FOR 1 FULL YEAR (UP TO
18 CYCLES)

PERJETA® (pertuzumab) is approved in combination with
Herceptin® (trastuzumab) and chemotherapy for patients with
HER2+ early breast cancer that has a high likelihood of coming back.

https://www.perjeta.com/patient.html

Is this old news? It came in my mail today.

illimae · July 2018

marijen, I think the new part is the additional of Perjeta in early stage treatment. As stage IV HER2+, this combo is standard protocol.

minustwo · July 2018

I agree. I know some women who had H&P along with neo-adjuvant chemo but still had to fight to get their insurance to pay for Perjeta the rest of the year after surgery.

marijen · July 2018

Oh good, then I'm glad I posted it. Thanks Illimae and MinusTwo. It says 18% more chance of recurrence for HER+

illimae · July 2018

yeah, 18% is not good. HER2 also likes the brain as I and many have discovered. Oh well, we do what we can.

Thanks for posting all, I read this often but don’t add much.

aterry · July 2018

Chemokaze, thanks for posting the Siddhartha Mukherjee article. Many times when people learn that I've just been treated for cancer they tell me about anti-cancer diets they've heard about. They are always very intense about these diets and are frustrated if I don't immediately embrace the diet. During my treatment I relied on the nutritionist at the Dubin Breast Center when I wasn't sure how to plan. I think it's great that there will be actual data about a specific approach.

mike3121 · July 2018

Something I came across:

https://medicalxpress.com/news/2018-07-scientists-sharpen-edges-cancer-chemotherapy.html

My wife is now on Halaven as her Xeloda failed her. She's tolerating it okay. Her ER/PR+ turned triple negative about 1 1/2 years ago and was put on Xeloda.

pi-xi · July 2018

Comparison of Treatment Outcomes with Breast-conserving Surgery plus Radiotherapy versus Mastectomy in Patients with Stage I Breast cancer: A Propensity Score-matched Analysis

Not that I had a choice in my surgery, but this wasn't a great abstract for me to see first thing in the morning. Good news for others though.

marijen · July 2018

CDC Opioid Restrictions Reading List | EDS and Chronic Pain News & Info - long list of links here

https://edsinfo.wordpress.com/pain/cdc-opioid-restrictions-reading-list/

marijen · July 2018

Get Ready for the Future!

Trackable Pill Technology and Smart Bottles

6 Replies

https://edsinfo.wordpress.com/2018/07/11/trackable...

Chemokaze · July 2018

Fighting Cancer With Cancer: Scientists Use CRISPR To Tweak Tumor Cells And Make Them Attack 'Their Own Kind'

http://flip.it/hq2KKN

(This article includes METASTATIC BREAST CANCER

marijen · July 2018

That’s funny! I hope it works

Lumpie · July 2018

Potential DNA damage from CRISPR has been 'seriously underestimated,' study finds

https://www.statnews.com/2018/07/16/crispr-potenti...

Research published on Monday (16 July 2018) suggests that... CRISPR-Cas9 can cause significantly greater genetic havoc than experts thought... perhaps enough to threaten the health of patients who would one day receive CRISPR-based therapy.... Some CRISPR'd cells might be missing a key anti-cancer mechanism ....

Lumpie · July 2018

Curing Metastatic Breast Cancer

http://ascopubs.org/doi/full/10.1200/JOP.2015.0089...

Metastatic breast cancer is generally considered incurable, and this colors doctor-patient interactions for patients with metastatic disease. Although true for most patients, there appear to be important exceptions, instances where long-term disease-free survival occurs. Although these instances are few in number, they suggest the possibility of cure. How will we move toward cure for a much larger population of patients with metastatic disease? This article outlines a potential research agenda that might move us toward that distant goal.

{article is from 2016 but interesting}

marijen · July 2018

A very interesting, honest and sobering article Lumpie, thanks for posting. Just as I suspected.

minustwo · July 2018

Wow Lumpie. Yes, thanks for posting. Since I had what was called a 'recurrence' after BMX, and the type 'mutated' from DCIS to IDC - this article makes sense of a lot of loose ends.

heidihill · July 2018

Lumpie, thanks for the link. I am a long-term survivor of mets at almost 11 years out. Just eyeballing those stats I will likely make it to 15, even 20.

"Studies of tumor-infiltrating lymphocytes in the adjuvant setting have suggested that their presence is a powerful predictor of outcome, suggesting that we already rely on the immune system for therapeutic impact even in the absence of immune-based therapies.^26"

This has been the only explanation that made sense to me, although I don't really know if my tumor had a lot of TILs. Given the outcome, it probably did.

I had neoadjuvant chemo, surgery, radiation and hormonal treatment.

I put my hopes on this article from 2001 when I started treatment in 2007, Can We Cure Limited Metastatic Breast Cancer? The odds were much lower then.

http://ascopubs.org/doi/full/10.1200/JCO.2002.20.3.620

marijen · July 2018

Heidihill, that’s great for you! May I ask why you didn’t start Tamoxifen until 2015?

marijen · July 2018

FDA Expands Ribociclib Breast Cancer Approval Under New Pilot Programs

https://onclive.cmail19.com/t/j-l-ntujruk-jrtrfkdyh-y/

marijen · July 2018

Optimal Duration of Adjuvant Endocrine Therapy Undecided in ER+ Breast Cancer

Caroline Seymour

Published: Tuesday, Jul 10, 2018

Www.onclive.com

Under breast cance

marijen · July 2018

Optimal Use With Adjuvant Endocrine Therapy Continues to Unfold in ER+ Breast Cancer

Caroline Seymour

Published: Monday, Jul 09, 2018

Excerpt

"You're treating 20 to 30 patients with a drug for 10 years to help one patient," said Denes. "We have to figure out how to better identify that one patient and let the other patients live happy lives."

Www.onclive.com