Triple-Negative Breast Cancer

This is a way for us to find each other, please add your post so everyone can be found. We can discuss on this thread (hope this works out!)

SOS Triple Negative Metastatic P.s Long Post I would like to ask for opinions regarding my mother’s case. She was first diagnosed with breast cancer in Albania in November 2018. The tumor was ER-negative, PR-negative, HER2-low (0)PD-L1 negative, and BRCA1/BRCA2 genetic testing was negative.She has also no possibility for…

I am in treatment and while others say I'm doing well, I haven't felt it. I was diagnosed with triple negative IDC in my left breast at 38 this year. Multi-focal, 2 tumors - 1.6 cm and 5 mm. They said node negative but then later my second opinion team, NCI, saw the first place biopsied the wrong node so I had to do it…

I think that we tn's need to have a sign up list like some of the other threads have...maybe put your age, and also what treatment you have had or are now having. What to do you think? I can start: age 50, diagnosed at age 49 1/2, lumpectomy, 4 AC Dose dense (every two weeks) and 4 Taxol, Dose Dense every 2 weeks. 35 rads…

I went threw 6 rounds of chemotherapy and 2 rounds of Keytruda. The Keytruda was damaging my lungs so I was not allowed to take it anymore. After having several rounds of the same chemo I developed a allergy to it which caused me to end up in the hospital. I will be finishing radiation on July 3rd and starting Capecitabine…

Hi, I'm Vita.My mom is Stage 4 Triple Negative breast cancer, now metastasis to liver. We have to choose this week which chemo... does anyone have any experience with these 2 listed above? Any info will be appreciated...

Triple-Negative Breast Cancer Treatment: Where Are We? Dr. Lisa Carey explains the latest research on TNBC treatments. Mar 7, 2025 About 10% to 15% of breast cancers are triple-negative. This means they don’t have receptors for the hormones estrogen or progesterone, and don’t have too many HER2 proteins. So, hormonal…

Good afternoon! I and my daughter both carry the FANCM TNBC gene. I’m a breast cancer survivor who was diagnosed in 2011 at age 43. I had a 1 cm DCIS, Stage 0, Solid/Grade 3 tumor and a subsequent bilateral mastectomy. In 2011, the only recognized breast cancer genes tested were BRCA1 and 2, and TP53 which were obviously…

Newly diagnosed here. TNBC stage 1b grade 3. I met with my BS, MO, and RO for the fist time yesterday. Breast MRI shows a 1.5cm mass that hasn’t grown since mammo and US a month ago and no nodes involved. So the plan is: -Surgery first (I am leaning towards SMX no recon) -Chemo: 4 rounds of TC spread 3 weeks apart -No…

Hi. I had TNBC in one breast. I underwent chemo and had a successful lumpectomy. The surgeon and oncologist have confirmed the cancer is gone. I start radiation on March 16 to reduce the risk of recurrence in the breast. The oncologist recommends I take the oral chemo drug, capecitabine, for 6 months to reduce the…

I was diagnosed with invasive ductal carcinoma grade 3, stage 1 and triple negative in my left breast. After some tests and an MRI, a large mass was found in my right breast. Now I am waiting for my biopsy in my right breast to see if cancer is there as well. This will change the surgery and chemo treatment. It is hard to…

originally diagnosed IDC grade 2 , stage 3A HR+ with Allred score 8/8 and HER2- at the age of 46, 10 years back . Surgery, chemo and radiation therapy done as part of treatment followed by 5 years of tamoxifen followed by 5 years of letrozole and Zolenic acid. Now got bone pain few months back. When done pet scan and MRI…

Hi everyone who sees this post. I am posting this for my mom's circumstance. She has been diagnosed with breast cancer since 2007, which was luminal A category. She had reoccurance in 2016 and has been living as a metastasis patient since then with hormone therapy. Recently she has been newly diagnosed with a TNBC cancer…

Final Results From Early Trials on a Vaccine to Prevent TNBC December 11, 2025 At the 2025 San Antonio Breast Cancer Symposium, Justin Johnson, PhD, presented a poster detailing the final results from three groups of people in a phase I trial on a vaccine to prevent triple-negative breast cancer. Listen to the episode to…

Can We Stop Fat From Fueling Triple-Negative Breast Cancer? November 18, 2025 Dr. Andrei Goga and his colleagues found that triple-negative breast cancer cells build molecular tunnels called gap junctions into nearby fat cells and use the fat cells’ energy for fuel. When the scientists blocked the gap junctions, the tumors…

A2 Biotherapeutics is looking to recruit people with metastatic TNBC to a study on a CAR T therapy. The mTNBC must have EGFR expression and have lost HLA-A*02 expression. If you meet this criteria and would like to participate in this trial, you can email the study contact at: ClinicalTrials@a2bio .com Or, directly email…

Has anyone with Triple Negative Breast Cancer taken Xeloda that went through chemotherapy and then had a double mastectomy and lymph nodes removed? I am going to have radiation but, my oncologist wants me to take Xeloda but, I want to hear some feed back.

Hello all. Just curious if everyone is still having MRIs? My oncologist and breast surgeon have different opinions on this and I'm leaning to just doing mammograms at this point. Concerned about all that contrast dye accumulating. I am a TNBC 12 year survivor and tested negative for the BRCA genes however my mom had breast…

I have not started treatment yet but have been told to do keynote 522, surgery and radiation. For multiple reasons I do not want to do chemo treatment at this time. The tumor has gone from 3 cm to 5 cm and there may or may not be lymph node involvement scans say no but doctors think may be. I would like to do surgery and…

Hi my name is Deanna and I am 48 I recently went to the ER for a lump that is really hurting. So I got an biopsy and a CT scan done , and went a couple of weeks ago to the surgical oncologist for the results. He went over the results with me and my family explaining different tests like the Hormone receptors and said that…

Sep 23, 2025 Triple-negative breast cancer may come back as hormone receptor-positive disease about a third of the time. Triple-negative breast cancer is negative for both estrogen and progesterone receptors. So, it’s hormone receptor-negative. People diagnosed with this type of breast cancer aren’t offered hormonal…

I didn’t achieve pCR after DMX. My oncologist doesn’t feel like Xeloda is aggressive enough for my next line of treatment for my TNBC. Trodelvy is on the table, but she’s also looking for drug trials I might be eligible for. Looking for others in a similar situation - what are you taking and what side effects are you…

Keytruda Improves Survival in Triple-Negative Breast Cancer September 15, 2024 People diagnosed with early-stage triple-negative breast cancer who received the immunotherapy Keytruda (chemical name: pembrolizumab) along with chemotherapy before and after surgery had better event-free survival — how long they lived without…

Hi all, I was diagnosed last week with clinical stage 1 grade 3 ki 67 90% er-, pr-, and waiting on FISH results to find out if I'm also HER2-. Tumor size is 14mm. My care team is recommending a lumpectomy first since my tumor is small even though it is very aggressive followed by 4-6 months of chemo then choosing either…

Top Breast Cancer Research at ASCO 2025 Dr. Eleonora Teplinsky explains DESTINY-Breast09, ASCENT-04, and SERENA-6. Jun 2, 2025 The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting featured five days of presentations and educational sessions on all types of cancer. Dr. Eleonora Teplinsky, a board-certified…

Triple-Negative Breast Cancer and the TRIM37 Protein Is the TRIM37 protein one reason why Black women are more likely to be diagnosed with triple-negative breast cancer? Dr. Sanchita Bhatnagar discusses her research. Apr 4, 2025 It’s been known for many years that Black women are twice as likely as white women to be…

Trodelvy and Keytruda as First Treatment for Metastatic TNBC: A New Standard of Care? May 30, 2025 People lived longer without the cancer growing when they received Trodelvy and Keytruda compared to the current standard treatment. Read more…

Camrelizumab Seems Promising As New Triple-Negative Breast Cancer Treatment Apr 14, 2025 Adding the immunotherapy medicine camrelizumab to chemotherapy offered better outcomes than chemotherapy alone for TNBC. Read more…

With so many forums and threads on this site to go through for information, I thought it would be a good idea for all of us in the UK to form a forum specifically for us, and to give our details and experiences in a compact manner. Anyone else in the world is welcome to join in. I was diagnosed with a very large tumour,…

Hi everyone, I'm caring for my mother who was diagnosed with Stage II Triple Negative Breast Cancer in November last year. She is the third generation along my maternal line to be diagnosed, but her genetic markers came out negative. She’s been undergoing chemotherapy for the past 5 months and is currently on Adriamycin…