Any FANCM Triple Negative Breast Cancer Gene sisters?
Good afternoon!
I and my daughter both carry the FANCM TNBC gene. I’m a breast cancer survivor who was diagnosed in 2011 at age 43. I had a 1 cm DCIS, Stage 0, Solid/Grade 3 tumor and a subsequent bilateral mastectomy.
In 2011, the only recognized breast cancer genes tested were BRCA1 and 2, and TP53 which were obviously negative for me.
Just wondered if there are any other women who share this gene and what you did for treatment. I’m thinking about having a prophylactic solpinga-oopherectomy to limit the chance of ovarian cancer as well.
Daughter isn’t quite 30 but her doctors now are taking her screening seriously.
All the best to you!
Mom of three
Comments
-
Hi @m0m2three ,
Thank you so much for sharing this. There’s really a lot of thought and care in how you’re approaching this, both for yourself and your daughter.
It’s amazing how much genetic testing has expanded since your diagnosis in 2011. Many people are now finding out about genes like FANCM that simply weren’t part of the conversation back then, so you’re definitely not alone in trying to figure out what it means and what to do with that information.
You may or may not hear from others here with the same gene, but there are quite a few members navigating newer or less common genetic findings and making similar decisions around screening and preventive surgery. These choices can feel big, and many people find it helpful to talk them through with a genetics specialist or a care team that can look at the full picture—personal history, family history, and risk tolerance.
It’s really encouraging to hear that your daughter’s doctors are taking her screening seriously at her age. That kind of proactive care can make a big difference and often brings some peace of mind. So important.
If anyone here has experience with FANCM, hopefully they’ll jump in and share. In the meantime, you’re asking thoughtful, important questions. You’re not alone in figuring this out. Please let us know any updates. 💛
0
