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Capecitabine or ctDNA Monitoring with TNBC
Hi. I had TNBC in one breast. I underwent chemo and had a successful lumpectomy. The surgeon and oncologist have confirmed the cancer is gone. I start radiation on March 16 to reduce the risk of recurrence in the breast. The oncologist recommends I take the oral chemo drug, capecitabine, for 6 months to reduce the…
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Calling all TNs
I think that we tn's need to have a sign up list like some of the other threads have...maybe put your age, and also what treatment you have had or are now having. What to do you think? I can start: age 50, diagnosed at age 49 1/2, lumpectomy, 4 AC Dose dense (every two weeks) and 4 Taxol, Dose Dense every 2 weeks. 35 rads…
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Am I being under-treated?
Newly diagnosed here. TNBC stage 1b grade 3. I met with my BS, MO, and RO for the fist time yesterday. Breast MRI shows a 1.5cm mass that hasn’t grown since mammo and US a month ago and no nodes involved. So the plan is: -Surgery first (I am leaning towards SMX no recon) -Chemo: 4 rounds of TC spread 3 weeks apart -No…
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Waiting for a second biopsy to learn the course of treatment
I was diagnosed with invasive ductal carcinoma grade 3, stage 1 and triple negative in my left breast. After some tests and an MRI, a large mass was found in my right breast. Now I am waiting for my biopsy in my right breast to see if cancer is there as well. This will change the surgery and chemo treatment. It is hard to…
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Multiple skeletal Mets Strongly ER positive BC originally now showing as TNBC
originally diagnosed IDC grade 2 , stage 3A HR+ with Allred score 8/8 and HER2- at the age of 46, 10 years back . Surgery, chemo and radiation therapy done as part of treatment followed by 5 years of tamoxifen followed by 5 years of letrozole and Zolenic acid. Now got bone pain few months back. When done pet scan and MRI…
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(Seek Help) Long Term Luminal A BC transformed into TNBC (Surgery done and under chemo)
Hi everyone who sees this post. I am posting this for my mom's circumstance. She has been diagnosed with breast cancer since 2007, which was luminal A category. She had reoccurance in 2016 and has been living as a metastasis patient since then with hormone therapy. Recently she has been newly diagnosed with a TNBC cancer…
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Podcast: Final Results From Early Trials on a Vaccine to Prevent TNBC
Final Results From Early Trials on a Vaccine to Prevent TNBC December 11, 2025 At the 2025 San Antonio Breast Cancer Symposium, Justin Johnson, PhD, presented a poster detailing the final results from three groups of people in a phase I trial on a vaccine to prevent triple-negative breast cancer. Listen to the episode to…
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Podcast: Can We Stop Fat From Fueling Triple-Negative Breast Cancer?
Can We Stop Fat From Fueling Triple-Negative Breast Cancer? November 18, 2025 Dr. Andrei Goga and his colleagues found that triple-negative breast cancer cells build molecular tunnels called gap junctions into nearby fat cells and use the fat cells’ energy for fuel. When the scientists blocked the gap junctions, the tumors…
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Clinical Trial Opportunity: Metastatic TNBC with EGFR expression and have lost HLA-A*02 expression
A2 Biotherapeutics is looking to recruit people with metastatic TNBC to a study on a CAR T therapy. The mTNBC must have EGFR expression and have lost HLA-A*02 expression. If you meet this criteria and would like to participate in this trial, you can email the study contact at: ClinicalTrials@a2bio .com Or, directly email…
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Capecitabine - Side Effects
I went threw 6 rounds of chemotherapy and 2 rounds of Keytruda. The Keytruda was damaging my lungs so I was not allowed to take it anymore. After having several rounds of the same chemo I developed a allergy to it which caused me to end up in the hospital. I will be finishing radiation on July 3rd and starting Capecitabine…
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Xeloda (Capecitabine)
Has anyone with Triple Negative Breast Cancer taken Xeloda that went through chemotherapy and then had a double mastectomy and lymph nodes removed? I am going to have radiation but, my oncologist wants me to take Xeloda but, I want to hear some feed back.
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Advice on MRI over 5 years post treatment
Hello all. Just curious if everyone is still having MRIs? My oncologist and breast surgeon have different opinions on this and I'm leaning to just doing mammograms at this point. Concerned about all that contrast dye accumulating. I am a TNBC 12 year survivor and tested negative for the BRCA genes however my mom had breast…
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Diagnosed with TNBC in April
I have not started treatment yet but have been told to do keynote 522, surgery and radiation. For multiple reasons I do not want to do chemo treatment at this time. The tumor has gone from 3 cm to 5 cm and there may or may not be lymph node involvement scans say no but doctors think may be. I would like to do surgery and…
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Just dignosed
Hi my name is Deanna and I am 48 I recently went to the ER for a lump that is really hurting. So I got an biopsy and a CT scan done , and went a couple of weeks ago to the surgical oncologist for the results. He went over the results with me and my family explaining different tests like the Hormone receptors and said that…
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TNBC Can Change Hormone Receptor Status If It Comes Back
Sep 23, 2025 Triple-negative breast cancer may come back as hormone receptor-positive disease about a third of the time. Triple-negative breast cancer is negative for both estrogen and progesterone receptors. So, it’s hormone receptor-negative. People diagnosed with this type of breast cancer aren’t offered hormonal…
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Triple Negative Stage IV
This is a way for us to find each other, please add your post so everyone can be found. We can discuss on this thread (hope this works out!)
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Didn’t achieve pCR. Next steps for TNBC?
I didn’t achieve pCR after DMX. My oncologist doesn’t feel like Xeloda is aggressive enough for my next line of treatment for my TNBC. Trodelvy is on the table, but she’s also looking for drug trials I might be eligible for. Looking for others in a similar situation - what are you taking and what side effects are you…
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Keytruda Improves Survival in Triple-Negative Breast Cancer
Keytruda Improves Survival in Triple-Negative Breast Cancer September 15, 2024 People diagnosed with early-stage triple-negative breast cancer who received the immunotherapy Keytruda (chemical name: pembrolizumab) along with chemotherapy before and after surgery had better event-free survival — how long they lived without…
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TN- Surgery first or chemo first and Lumpectomy or Mastectomy?
Hi all, I was diagnosed last week with clinical stage 1 grade 3 ki 67 90% er-, pr-, and waiting on FISH results to find out if I'm also HER2-. Tumor size is 14mm. My care team is recommending a lumpectomy first since my tumor is small even though it is very aggressive followed by 4-6 months of chemo then choosing either…
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Top Breast Cancer Research at ASCO 2025
Top Breast Cancer Research at ASCO 2025 Dr. Eleonora Teplinsky explains DESTINY-Breast09, ASCENT-04, and SERENA-6. Jun 2, 2025 The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting featured five days of presentations and educational sessions on all types of cancer. Dr. Eleonora Teplinsky, a board-certified…