Apr 7, 2022 06:47PM obsolete wrote:
Hello Canada & Alaska, best wishes for healthful healing to Boo. Friendly springtime 🌼 greetings to Rain and hoping everyone has a pleasant season. Peace 🕊️ & good intentions 🙏
CONSTRUCTION OF A PROGNOSTIC NOMOGRAM MODEL FOR PATIENTS WITH MUCINOUS BREAST CANCER( (2022)
"... there is a lack of reports of large sample studies on MBC, which predisposes to under-treatment or over-treatment."
"Univariate analysis of the survival of 2,776 MBC patients in the modeling group revealed that the 3- and 5-year survival rates of patients were linked to their age, ethnicity, marital status, T stage, N stage, M stage, surgery, radiotherapy, and chemotherapy, but NOT to histological grade, lesion location, PR status, ER status, or HER-2 status as indicated in Table."
"... age at diagnosis is the greatest contributor to the prognosis, followed, respectively, by M stage, TNM stage, ethnicity, surgery status, and radiotherapy status. The nomogram shows that the use of radiotherapy is beneficial for patients with MBC."
"... only lymph node involvement is considered chemotherapeutic, regardless of the T stage."
"Furthermore, lymph node involvement was found to be unrelated to tumor size in one investigation."
"It has been shown that patients treated with breast-conserving surgery in stage T1-2 MBC have a better prognosis than those who undergo mastectomy, particularly in patients aged 50–79 years;"
"In the current study, a total of 2,043 (51.5%) patients received radiotherapy and 1,921 (48.4%) did not. The nomogram shows that the use of radiotherapy is beneficial for patients with MBC."
"It has been reported in the literature that the reason for the low efficacy of chemotherapy is that mucus accounts for most of the total volume in MBC cells, forming a large pool of mucin, resulting in inconsistency between clinical or imaging assessment of chemotherapy efficacy and mucinous carcinoma pathology. Despite the effective elimination of malignant cells by chemotherapy, the mucin pool remains."