Topic: Taxotere, Carboplatin and Herceptin

Forum: Chemotherapy - Before, During, and After — Regimens, side effects, and support from others going through chemo.

Posted on: Apr 5, 2007 09:04PM - edited Aug 9, 2022 07:58PM by moderators

Posted on: Apr 5, 2007 09:04PM - edited Aug 9, 2022 07:58PM by moderators

cinrae123 wrote:

Anyone out there on taxotere, carboplatin, and herceptin? I am starting this program in May, I will be doing it every week instead of every third week...and would like to know what sort of side effects anyone has had. Examples:hair loss, nausea, vomiting, etc. I chose the every week routine as I was encouraged by a woman in the drs. office that is halfway thru and has not had any hair loss. I was thinking that because each cycle is spread out every week instead of a big dose once,,,,,that maybe that has something to do with it. I am having a difficult time with the thought of losing my hair. Silly I know...everyone says it grows back...but it's just a personal thing for me. So anyone out here that did TCH every week? I would truly like to hear from you.

Thank you.

Cindy Dx 1/2007, IDC, 1cm, Stage I, Grade 3, 0/3 nodes, ER-/PR-, HER2+
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Dec 18, 2015 06:57PM GraceN wrote:

Thank you so much for your response! Good to know it can let up eventually. My Dr seems to think we need to find which one caused me this violent a reaction and then adjust the cocktail accordingly but since he gave me a half dose this week of the Taxotere, I'm not sure if I can say for sure if this is the biggest problem or not. It did give me some D for 2 days but it was controllable whereas the first full round it was not. Perhaps my body will eventually just get used to it like yours did and I can stay on this routine. So many unknowns! I find Taxotere to be hard on my in many ways though. I get a tightness in my chest and racking pains that come from my back around my ribs. Just awful pain, but fortunately they are short lived but scary when they come! Anyway... I go back Monday for the Herceptin and Perjeta alone "test" to see if that's it. I really thought it would be Taxotere but now I don't really know. They all cause it some! LOL! Thanks for the help!
Dx 10/28/2015, ILC/IDC, Right, 5cm, Stage IIIA, Grade 3, 0/2 nodes, ER+/PR+, HER2+, Targeted Therapy 11/16/2015 Herceptin (trastuzumab) Chemotherapy 11/16/2015 Abraxane (albumin-bound or nab-paclitaxel), Carboplatin (Paraplatin) Targeted Therapy 11/16/2015 Perjeta (pertuzumab) Chemotherapy 11/16/2015 Carboplatin (Paraplatin) Chemotherapy 11/16/2015 Taxotere (docetaxel) Surgery 4/5/2016 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Left
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Dec 18, 2015 06:59PM GraceN wrote:

Thanks so much! It's a barrel of laughs huh? Hope you are doing well now!!!

Dx 10/28/2015, ILC/IDC, Right, 5cm, Stage IIIA, Grade 3, 0/2 nodes, ER+/PR+, HER2+, Targeted Therapy 11/16/2015 Herceptin (trastuzumab) Chemotherapy 11/16/2015 Abraxane (albumin-bound or nab-paclitaxel), Carboplatin (Paraplatin) Targeted Therapy 11/16/2015 Perjeta (pertuzumab) Chemotherapy 11/16/2015 Carboplatin (Paraplatin) Chemotherapy 11/16/2015 Taxotere (docetaxel) Surgery 4/5/2016 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Left
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Dec 19, 2015 10:34PM Jerseygirl927 wrote:

did not have perjetta, but still had diarrhea too, so your cocktail will be what the dr is trying to rule out.

As for the dental issues, will talk to dr after holidays, cause when I bite on hard things like nuts, this tooth hurts, so am hoping it's not cracked, nor the gum/jaw either, but something is up

Surgery 1/12/2015 Lymph node removal: Left, Sentinel; Mastectomy: Left, Right Dx 1/14/2015, ILC/IDC, Left, 1cm, Stage IA, Grade 1, 0/5 nodes, ER+/PR+, HER2+ Chemotherapy 2/25/2015 Carboplatin (Paraplatin), Taxol (paclitaxel) Hormonal Therapy 5/29/2015 Femara (letrozole) Dx IDC, ER+/PR+, HER2+ Dx ILC, 1cm, Stage IA, 0/1 nodes, ER+/PR+, HER2+
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Dec 20, 2015 06:33AM MaggieMae123 wrote:

Hi, I had diarrhea that wouldn't go away and it ended up being C Diff infection. I think you should have your Dr. check that for you. I am taking the TCH chemo and nothing worked on my problem until they found out that I had C diff. There is a special antibiotic that gets rid of it. Good luck to you.

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Dec 20, 2015 09:55PM lindakr wrote:

Grace - I didn't get Perjeta, because, like Lago, it wasn't available 5+ years ago when I received treatment, but I did get the Taxotere, Carboplatin and Herceptin, I had a little diarrhea while getting the chemos for a couple of days nothing bad. But mainly I wanted to say that I'm here and still no evidence of disease 5 1/2 years later without the perjeta, so if you have to stop that med, the other 3 are still very effective for most people.

Linda

Modified Radical MX w/axillary dissection; 6xTCH, Hercpetin for a year, Rads, trying 3rd AI Aromasin. No Reconstruction. Lymphedema. Dx 3/19/2010, IDC, 4cm, Stage IIIA, Grade 2, 5/18 nodes, ER+/PR+, HER2- Surgery 4/2/2010 Lymph node removal; Lymph node removal (Left): Underarm/Axillary; Mastectomy; Mastectomy (Left) Targeted Therapy 5/15/2010 Herceptin (trastuzumab) Chemotherapy 5/15/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy 9/15/2010 Arimidex (anastrozole), Aromasin (exemestane), Femara (letrozole) Radiation Therapy 9/25/2010 Whole breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Dec 20, 2015 10:14PM lago wrote:

I did TCH too but didn't get diarrhea, I was constipated. Didn't get any nausea either.

DONE!! goo.gl/IoaN6U • Tattoos 2.7.2012 • Nipples 10.6.2011 • Exchange 6.24.2011 • Chemo 1.18. 2011 • BMX 8.31.2010 Dx 7/13/2010, IDC, 5cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2-
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Dec 22, 2015 09:02AM specialk wrote:

I was a TCH peep without Perjeta, since it had not been approved yet, and had the Big D for ten days straight after each of the six infusions.

BMX w/ TE 11/1/10, ALND 12/6/10. 16 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 2013-2018. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+, IHC
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Dec 26, 2015 06:09PM GraceN wrote:

Thank you all so much for your help! I ended up getting the big D for days 6-7 and the Dr told me I can't have Taxotere. He has switched me to Abraxane which is a weekly dose instead of every three weeks so I will get it with my Herceptin. I did fine with the Perjeta except my insurance just sent a note that it is not medically necessary and did not pay the over $14k bill for it. Yikes! Praying we can get that one worked out!

Has anyone had Abraxane instead of Taxotere? Apparently they are in the same family of drugs but the ABraxane tends not to bother people as much with gastric issues so that's why that choice. My concern is that it was not what was used for the trials so I don't have that to keep me going, but hopefully this will be just as effective. I start my new 4 drug dose Monday.

Happy New Year to all of you!
Dx 10/28/2015, ILC/IDC, Right, 5cm, Stage IIIA, Grade 3, 0/2 nodes, ER+/PR+, HER2+, Targeted Therapy 11/16/2015 Herceptin (trastuzumab) Chemotherapy 11/16/2015 Abraxane (albumin-bound or nab-paclitaxel), Carboplatin (Paraplatin) Targeted Therapy 11/16/2015 Perjeta (pertuzumab) Chemotherapy 11/16/2015 Carboplatin (Paraplatin) Chemotherapy 11/16/2015 Taxotere (docetaxel) Surgery 4/5/2016 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Left
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Dec 26, 2015 07:35PM lago wrote:

Grace. Abraxane does have SE but not as many as Taxotere. It's more expensive so insurance will not pay unless you have to have it. Like in your case you can't do Taxotere. Don't worry. You are getting good shit

DONE!! goo.gl/IoaN6U • Tattoos 2.7.2012 • Nipples 10.6.2011 • Exchange 6.24.2011 • Chemo 1.18. 2011 • BMX 8.31.2010 Dx 7/13/2010, IDC, 5cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2-
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Dec 26, 2015 08:13PM GraceN wrote:

Thanks lago! Good to know about the Abraxane not being paid by insurance unless necessary. I just found out they didn't pay my Perjeta as not medically necessary so I may be in for a fight. Ugh. So glad to know to ask about this as well before treatment Monday!

Dx 10/28/2015, ILC/IDC, Right, 5cm, Stage IIIA, Grade 3, 0/2 nodes, ER+/PR+, HER2+, Targeted Therapy 11/16/2015 Herceptin (trastuzumab) Chemotherapy 11/16/2015 Abraxane (albumin-bound or nab-paclitaxel), Carboplatin (Paraplatin) Targeted Therapy 11/16/2015 Perjeta (pertuzumab) Chemotherapy 11/16/2015 Carboplatin (Paraplatin) Chemotherapy 11/16/2015 Taxotere (docetaxel) Surgery 4/5/2016 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Left

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