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Sep 14, 2018 09:10AM
Case Report Describes 4 Breast Cancer Cases Post Transplant
case report published recently in the American Journal of Transplantation.
...reported four cases of breast cancer transmission to transplant recipients from a single organ donor. The donor had no relevant medical history and donated her kidneys, lungs, liver, and heart. ...four recipients developed donor-derived breast cancer, which was proven by DNA microsatellite. As a result of the donor-derived breast cancer, the double-lung recipient, left-kidney recipient, and liver recipient died. After diagnosis of the breast cancer in the right-kidney recipient, the patient underwent transplant nephrectomy, his immunosuppression was stopped, chemotherapy was initiated, and despite having widely metastasized disease he achieved complete remission.
"This extraordinary case points out the often fatal consequences of donor-derived breast cancer and suggests that removal of the donor organ and restoration of immunity can induce complete remission," the authors write.
"If adventures will not befall a young lady in her own village, she must seek them abroad." "Buy the ticket, take the ride."
2015, DCIS/IDC, Right, 3cm, Stage IIA, Grade 3, 0/1 nodes, ER-/PR-, HER2+ (IHC)
1/14/2016 Herceptin (trastuzumab)
1/14/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel)
2017, IDC, Stage IV, metastasized to liver, ER-/PR-, HER2+