Topic: Breaking Research News from sources other than Breastcancer.org

Forum: Clinical Trials, Research News, Podcasts, and Study Results — Share your research articles, interpretations and experiences here. Let us know how these studies affect you and your decisions.

Posted on: Nov 21, 2017 12:31AM - edited Nov 21, 2017 12:35AM by lumpie

Posted on: Nov 21, 2017 12:31AM - edited Nov 21, 2017 12:35AM by lumpie

lumpie wrote:

I watch for research news on breast cancer, treatments, etc., and frequently see interesting articles. There is a topic on BCO called "Breaking Research News from Breastcancer.org." One of the moderators suggested that another topic might be appropriate for posting links and synopses of reports on research found elsewhere. So here it is! Please post links to reports on research form reliable sources. Thanks for sharing!

"We must be willing to let go of the life we have planned, so as to have the life that is waiting for us." "If adventures will not befall a young lady in her own village, she must seek them abroad." "Buy the ticket, take the ride." Dx 2015, DCIS/IDC, Right, 3cm, Stage IIA, Grade 3, 0/1 nodes, ER-/PR-, HER2- Chemotherapy 1/14/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Targeted Therapy 1/14/2016 Herceptin (trastuzumab) Dx 2017, IDC, Stage IV, metastasized to liver, ER-/PR-, HER2- Surgery Lumpectomy; Lumpectomy (Right) Surgery Lumpectomy; Lumpectomy (Right) Radiation Therapy Whole breast: Breast
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Oct 30, 2021 06:03PM lillyishere wrote:

I have been eating nuts every day for many years and I keep them at work, car, home even though my kids are allergic to tree nuts. I even mix nuts with honey and eat them as dessert. Since starting letrozole I am finding them difficult to digest and I don't eat as much anymore.

Salamandra, you can find them cheap at Costco.

“Within five years, cancer will have been removed from the list of fatal maladies.” That was the optimistic promise to U.S. President William Howard Taft in 1910 when he visited Buffalo’s Gratwick Laboratory, “What’s taking so long?” Dx 7/31/2019, ILC, Left, <1, Stage IIA, 2/5 nodes, ER+/PR-, HER2- Hormonal Therapy 7/31/2019 Aromasin (exemestane), Femara (letrozole) Surgery 9/1/2019 Lymph node removal (Left); Mastectomy (Left): Nipple Sparing; Mastectomy (Right): Nipple Sparing; Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Surgery 9/1/2019 Mastectomy (Left): Nipple Sparing; Mastectomy (Right): Nipple Sparing; Prophylactic mastectomy (Right) Surgery 9/19/2019 Lymph node removal; Mastectomy; Mastectomy (Left); Mastectomy (Right); Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Hormonal Therapy 11/29/2019 Femara (letrozole) Hormonal Therapy 12/1/2019 Femara (letrozole), Aromasin (exemestane) Dx LCIS/ILC, Both breasts, 2/5 nodes, ER+/PR-, HER2-
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Oct 30, 2021 07:00PM minustwo wrote:

Agree about the Costco prices. Yes walnuts are high on all the 'good' lists. Unfortunately I am allergic to walnuts & macadamia nuts - but I eat all the rest.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Oct 31, 2021 06:07AM rah2464 wrote:

Walnuts are good for your brain as well. Here in Ky you can find walnuts for free if you want to go to the trouble to crack them open yourself.

Dx 5/23/2018, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- Surgery 6/27/2018 Mastectomy; Mastectomy (Left); Mastectomy (Right); Reconstruction (Left): Silicone implant; Reconstruction (Right): Silicone implant Hormonal Therapy 7/27/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Oct 31, 2021 08:14PM karenfizedbo15 wrote:

Ooohh yes good to see you Lumpie and a real pic of Cure-ious!

Surgery 9/7/2007 Lymph node removal; Mastectomy; Mastectomy (Right); Reconstruction (Right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2- Dx 2021, Stage IV, metastasized to bone Chemotherapy 2/4/2021 Xeloda (capecitabine) Hormonal Therapy Femara (letrozole) Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib)
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Nov 2, 2021 07:58AM homemom wrote:

I'm wondering, in these instances where funding a human trial is an issue, does Metavivor come in to help fund? I give 2% of my net commissions to a handful of charities and of course Metavivor is one and the next one up for a check.

Dx 3/31/2014, IDC, 2cm, Stage IIB, Grade 1, 3/29 nodes, ER+/PR+, HER2- Surgery 4/15/2014 Lumpectomy; Lumpectomy (Left) Surgery 5/6/2014 Lymph node removal; Lymph node removal (Left): Underarm/Axillary; Mastectomy; Mastectomy (Left); Reconstruction (Left): Tissue Expander Chemotherapy 5/30/2014 AC Chemotherapy 7/25/2014 Taxol (paclitaxel) Radiation Therapy 10/16/2014 Hormonal Therapy 12/15/2014 Arimidex (anastrozole)
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Nov 2, 2021 09:29AM gokale4320 wrote:

I received a response from Bayer about the emails I have been sending with requests for ErSO clinical trials:

Thank you for your inquiry regarding one of our drugs in development, ErSO. As you may have read, it has shown promising results in pre-clinical models of breast cancer. However, before it can be tried in humans, additional safety tests (such as in primates) must be undertaken, and that is where the compound currently is in development. We try to move our compounds through development as quickly as possible, but at the same time we have to take the prudent steps to ensure that the compounds are safe and provide the potential benefits we are striving to achieve (and thus the tests in other species such as primates). Because of these necessary steps the drug is not currently available for trials in humans. However, we hope to be able to provide an update on the status of the program before the end of the year.

If you would like to contact me in a 6-8 weeks, I may be able to give you a more definitive schedule.

You should know that Bayer posts its human clinical trials for all of its drugs on clinicaltrials.gov and that is another source for ongoing (or soon to start) clinical trials.

I hope that your doctors find ways to control your cancer in the meantime.

Sincerely,

Joseph Germino, MD, PhD

Vice President USMA

Bayer Healthcare

Dx: January 2017, IDC, Stage IIa, 1/23 nodes, <1cm Chemo 2/16/17 Cytoxan Taxotere x4 Radiation 6/8/2017, natural alternative to tamoxifen 3/2021 Stage 4 - mets to bones. Ibrance and Letrozole and Xgeva Dx 1/2017, IDC, Right, <1cm, Stage IIA, Grade 2, 1/23 nodes, ER+/PR+, HER2-
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Nov 2, 2021 09:38AM joynerl wrote:

WOW, Kale!! Great job, and thanks so much!

--Lynn Dx 12/1990, IDC, Left, <1cm, Stage IIA, ER+ Surgery 1/1/1991 Lymph node removal (Left); Mastectomy (Left): Simple; Reconstruction (Left): Nipple reconstruction, Tissue Expander Surgery 1/2/1991 Lymph node removal; Mastectomy; Mastectomy (Left); Reconstruction (Left): Nipple reconstruction, Saline implant Chemotherapy 1/15/1991 CMF Chemotherapy 1/22/1991 CMF Hormonal Therapy 6/30/1991 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 10/31/2002 Evista (raloxifene) Hormonal Therapy 2/1/2017 Dx 2/9/2017, IDC, Left, 1cm, Stage IV, metastasized to bone, ER+/PR-, HER2- Hormonal Therapy 2/13/2017 Faslodex (fulvestrant) Targeted Therapy 2/23/2017 Ibrance (palbociclib) Hormonal Therapy 3/5/2017 Faslodex (fulvestrant) Targeted Therapy 3/5/2017 Ibrance (palbociclib) Radiation Therapy 1/9/2019 External Local Metastases 1/9/2019 Radiation therapy: Bone Chemotherapy 1/17/2019 Xeloda (capecitabine) Chemotherapy 2/22/2019 Other Radiation Therapy 10/27/2020 External: Lymph nodes Targeted Therapy 1/1/2022 Afinitor (everolimus) Hormonal Therapy 1/1/2022 Aromasin (exemestane) Targeted Therapy 1/1/2022 Afinitor (everolimus) Hormonal Therapy 1/1/2022 Aromasin (exemestane)
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Nov 2, 2021 09:40AM laughinggull wrote:

Go Kale!

ACx4, THPx4, HP (to complete 1y); Nerlynx (1y); AI (expected 10y), Surgery: BMX + ALND, Reconstruction, Oophorectomy. Radiation. Dx 10/26/2017, IDC, Right, 3cm, Stage IIB, Grade 3, 2/6 nodes, ER+/PR+, HER2-
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Nov 2, 2021 10:31AM simone60 wrote:

GoKale,

Wow, it's wonderful he responded to you. Thanks for sharing.

Dx 7/2001, IDC, Right, 1cm, Stage IIIA, Grade 3, 7/13 nodes, ER+/PR+, HER2- Dx 1/2019, IDC, 1cm, Stage IV, metastasized to bone/other, ER+/PR+, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Femara (letrozole)
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Nov 2, 2021 10:56AM mocogram wrote:

GoKale, thank you so much for taking the initiative on this. Wonderful that you received what appears to be a personalized response. Can you share the email address you used to contact Mr. Germino?

Praying that ErSO reaches human trial phase soon and that it actually works! I'm very cautiously optimistic.

Dx 5/2016, ILC, Left, Stage IIB, ER+, HER2- Surgery 7/28/2016 Lumpectomy; Lumpectomy (Left) Chemotherapy 9/19/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Dx ILC, Other, Stage IV, ER+/PR+, HER2+, IHC Radiation Therapy Breast Hormonal Therapy Femara (letrozole) Targeted Therapy Ibrance (palbociclib) Targeted Therapy Tukysa (tucatinib) Chemotherapy Xeloda (capecitabine) Targeted Therapy Herceptin (trastuzumab)

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