Topic: Halaven - Day 1

Forum: Stage IV/Metastatic Breast Cancer — Please respect that this forum is for members with stage IV/metastatic breast cancer ONLY. There is a separate forum for caregivers and friends: Caring for Someone with Stage IV or Mets.

Posted on: Dec 14, 2010 12:05PM

Posted on: Dec 14, 2010 12:05PM

PJB wrote:

So, I'm the first person on this newly approved chemo at my med center. Lots of people who told me side effects.... They had a fancy dinner put on by the drug company last night so they all would know about it... :) Funny, no one gave ME steak and shrimp.  

Anyway, got hooked up to some saline as usual (altho, my onc's nurse wasn't sure why. She suggested since they charge so much, they had to do something... Apparently, it's unnecessary) The drug itself comes in a little syringe and they put it into the line over 5 minutes. Then, unhook you and you're done. All told, getting hooked up and waiting for pharmacy to get the drug over, etc., took about 30 minutes. 

Main SE's are neuropathy (have it, thanks to Ixempra), drop in blood counts (they say to plan on it next week), hair loss (already have that...), they'll watch liver enzymes (they're up from when I had my last Ixempra, but not too bad and tumor markers are the same... 

So, we'll see... I'll let you guys know what comes up down the road. I'll have it again next week, then a week off. Hopefully, it'll kill cancer like gangbusters.

Thanks for all your good wishes,

Paula 

May 2004, Stage 2 IDC. Recurrence in 2005. On Femara til mets diagnosis in Feb 2009. On Faslodex 8/11. Brain mets in April 2012. Progression in liver 6/12. On to Etoposide. Dx mets, ER+/PR+, HER2-
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Jul 31, 2012 01:05AM eag1954 wrote:

You'd better believe I can relate~~  Your rant is mild.  Considering the way I feel after chemo, I could go on and on.  I nw have diarrhea to.  I've been on Halaven for over a year and I really do think the side effects get worse!  I know treatment is a necessary evil, but I dread day 1 on Thursday!!!! 

Elizabeth Dx 4/2011, IDC, 2cm, Stage IV, 3/14 nodes, mets, ER+/PR+, HER2- Chemotherapy 4/24/2011 Halaven (eribulin)
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Jul 31, 2012 08:33AM SPAMgirl wrote:

I'm still on the constipation side of life and I'm 4 months in. My onc told me yesterday that the SE are cumulative. She also told me she's seen a lot of success with patients under 50-60, but patients older than that do not have much success.

mets to liver, bone and brain Radiation Therapy 3/5/2010 Breast, Lymph nodes Surgery 9/1/2010 Mastectomy: Left, Right; Reconstruction (left): Nipple reconstruction, Tissue expander placement; Reconstruction (right): Nipple reconstruction, Tissue expander placement Chemotherapy 9/26/2010 AC + T (Taxol) Hormonal Therapy 2/19/2012 Arimidex (anastrozole) Dx 2/20/2012, IDC, 2cm, Stage IV, Grade 2, 4/16 nodes, mets, ER+/PR-, HER2+ Targeted Therapy 2/26/2012 Herceptin (trastuzumab) Chemotherapy 2/26/2012 Navelbine (vinorelbine) Radiation Therapy 3/16/2012 Bone Chemotherapy 4/5/2012 Halaven (eribulin) Hormonal Therapy 11/4/2012 Faslodex (fulvestrant) Targeted Therapy 11/4/2012 Herceptin (trastuzumab) Targeted Therapy 11/4/2012 Perjeta (pertuzumab) Chemotherapy 11/4/2012 Taxotere (docetaxel) Chemotherapy 3/31/2013 Adriamycin (doxorubicin) Chemotherapy 6/16/2013 Xeloda (capecitabine) Targeted Therapy 6/23/2013 Tykerb (lapatinib)
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Jul 31, 2012 09:24AM holdontohope wrote:

My tumor makers are down another 300 pts.  Since going on Halaven they have dropped from over 900 to just over 300.  And with having to postpone treatments because of low counts, I have only received 40% of the dosage I should have had during this time period.

I am feeling hopeful!

So sorry to hear about the diarrhea issues.  I haven't experienced that yet.

Dx Stage IV, mets, ER+/PR+, HER2-
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Aug 2, 2012 08:56AM K-Lo wrote:

Hey, yall, have you ever noticed that one or two of the chemo nurses is a rebel?  Every other nurse has sat down and patiently pushed this Halaven over 5 minutes.  Then Ms. Grumpy comes over and shwooosh , its in as fast as she can push the plunger. 

So, last time I had her, I said, " Hey, K____, why is it that some people push Halaven slow and some fast?  Whats the reason behind it?"   She said, "I dunno, Ill check with pharmacy, but I thought it was just push".

When she got the drug, she sat down and pushed it slowly.

You know, if a rule is stupid or wrong, tell everyone.  But if there's a reason for caution, maybe something bad has happened to someone.  Like kidney failure, who  knows?  (I cant find it in literature)

Kathy Dx 8/30/2010, IDC, 4cm, Stage IV, 8/12 nodes, ER+/PR+, HER2-
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Aug 2, 2012 09:34AM SPAMgirl wrote:

Good job on being your own advocate. You probably helped others. Good job !

mets to liver, bone and brain Radiation Therapy 3/5/2010 Breast, Lymph nodes Surgery 9/1/2010 Mastectomy: Left, Right; Reconstruction (left): Nipple reconstruction, Tissue expander placement; Reconstruction (right): Nipple reconstruction, Tissue expander placement Chemotherapy 9/26/2010 AC + T (Taxol) Hormonal Therapy 2/19/2012 Arimidex (anastrozole) Dx 2/20/2012, IDC, 2cm, Stage IV, Grade 2, 4/16 nodes, mets, ER+/PR-, HER2+ Targeted Therapy 2/26/2012 Herceptin (trastuzumab) Chemotherapy 2/26/2012 Navelbine (vinorelbine) Radiation Therapy 3/16/2012 Bone Chemotherapy 4/5/2012 Halaven (eribulin) Hormonal Therapy 11/4/2012 Faslodex (fulvestrant) Targeted Therapy 11/4/2012 Herceptin (trastuzumab) Targeted Therapy 11/4/2012 Perjeta (pertuzumab) Chemotherapy 11/4/2012 Taxotere (docetaxel) Chemotherapy 3/31/2013 Adriamycin (doxorubicin) Chemotherapy 6/16/2013 Xeloda (capecitabine) Targeted Therapy 6/23/2013 Tykerb (lapatinib)
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Aug 5, 2012 08:18PM menan wrote:

K-Lo - My last one did the push really fast but seemed distracted and then found out anoter patient had had a reaction to Taxotere.  And didn't someone say they had stroke like symptoms from Halavan?  I wish we would get the same nurses every time.  I might make that request and see what happens.

Do any of you Stage 4/high risk feel like the nurses are stand offish to us?  I notice some seem to visit more with other patients and ask about their families.  Seems I get different nurses every time.

PET Scan  Wed. to see is Halavan is still working.  My hair is growing back but I'm still getting flu feeling and tired!  See my MO on Thur for results and hopefully another dose.  And I'm still at constipation phase but handling it with senna.

These are my good few days so I am going to  staRT LIVING.  I have been being real conservative - staying away from crowds, avoiding germs and staying home.  You all put me to shame so I plan to get more active.

Nancy B Dx 12/22/2007, IBC, Stage IV, Grade 3, 14/15 nodes, ER-/PR-, HER2-
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Aug 6, 2012 01:37PM SPAMgirl wrote:

My nurse just gave it ti me as a flu shot. Not even sub q. Just right in my belly. Head nurse just called me to tell me they know don't know if it will work since it didn't go straight into my blood stream. They are investigating now.

mets to liver, bone and brain Radiation Therapy 3/5/2010 Breast, Lymph nodes Surgery 9/1/2010 Mastectomy: Left, Right; Reconstruction (left): Nipple reconstruction, Tissue expander placement; Reconstruction (right): Nipple reconstruction, Tissue expander placement Chemotherapy 9/26/2010 AC + T (Taxol) Hormonal Therapy 2/19/2012 Arimidex (anastrozole) Dx 2/20/2012, IDC, 2cm, Stage IV, Grade 2, 4/16 nodes, mets, ER+/PR-, HER2+ Targeted Therapy 2/26/2012 Herceptin (trastuzumab) Chemotherapy 2/26/2012 Navelbine (vinorelbine) Radiation Therapy 3/16/2012 Bone Chemotherapy 4/5/2012 Halaven (eribulin) Hormonal Therapy 11/4/2012 Faslodex (fulvestrant) Targeted Therapy 11/4/2012 Herceptin (trastuzumab) Targeted Therapy 11/4/2012 Perjeta (pertuzumab) Chemotherapy 11/4/2012 Taxotere (docetaxel) Chemotherapy 3/31/2013 Adriamycin (doxorubicin) Chemotherapy 6/16/2013 Xeloda (capecitabine) Targeted Therapy 6/23/2013 Tykerb (lapatinib)
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Aug 6, 2012 09:23PM menan wrote:

WOW Spam!!    

And I thought it was bad having to remind nurses I'm allergic to tagaderm!!  I would call my MO and ask what they found out just to make sure he knows what happened.  I worked in a nursing home passing meds so I know alot of nurse's error never get reported to Drs.

Holdontohope- Good work on the markers!  Are you sure it isn't a 40% reduction?  I was at that up until June and now it is 50%.  

And btw, I will be 62 the end of September so hope I'm still unique and Halaven is working.  In December, I will be 5 years TNIBC and part of the 40% alive, but who's counting?

Nancy B Dx 12/22/2007, IBC, Stage IV, Grade 3, 14/15 nodes, ER-/PR-, HER2-
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Aug 7, 2012 09:57AM SPAMgirl wrote:

I just want to be sure. Does everyone get their Haleven as a push in their IV into their chemo port, or do you get it like a flu shot. I've always gotten it through my Chemo port, but I feel awful after getting like a flu shot yesterday.

mets to liver, bone and brain Radiation Therapy 3/5/2010 Breast, Lymph nodes Surgery 9/1/2010 Mastectomy: Left, Right; Reconstruction (left): Nipple reconstruction, Tissue expander placement; Reconstruction (right): Nipple reconstruction, Tissue expander placement Chemotherapy 9/26/2010 AC + T (Taxol) Hormonal Therapy 2/19/2012 Arimidex (anastrozole) Dx 2/20/2012, IDC, 2cm, Stage IV, Grade 2, 4/16 nodes, mets, ER+/PR-, HER2+ Targeted Therapy 2/26/2012 Herceptin (trastuzumab) Chemotherapy 2/26/2012 Navelbine (vinorelbine) Radiation Therapy 3/16/2012 Bone Chemotherapy 4/5/2012 Halaven (eribulin) Hormonal Therapy 11/4/2012 Faslodex (fulvestrant) Targeted Therapy 11/4/2012 Herceptin (trastuzumab) Targeted Therapy 11/4/2012 Perjeta (pertuzumab) Chemotherapy 11/4/2012 Taxotere (docetaxel) Chemotherapy 3/31/2013 Adriamycin (doxorubicin) Chemotherapy 6/16/2013 Xeloda (capecitabine) Targeted Therapy 6/23/2013 Tykerb (lapatinib)
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Aug 7, 2012 10:54AM menan wrote:

Spam - through my port     And I really would call my Dr. if I had that happen and then felt awful.     

Nancy B Dx 12/22/2007, IBC, Stage IV, Grade 3, 14/15 nodes, ER-/PR-, HER2-

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