Feb 22, 2018 06:48PM - edited Feb 22, 2018 07:01PM by Meow13
Oncodx is an indicator. My score was 34 and chose not to do chemo. As it turns out my lack of pr receptors and high estrogen 95% and being post menopausal I chose AI drugs. Going on 7 years NED. I also was not grade 3 but barely grade 2. My doctors did recommend chemo but I didn't feel the overwhelming need since my oncodx score was based on tamoxifen not AI drugs and being pr- the tamoxifen is proven not as effective as AI.
It will probably take more time to get the data on AI vs tamoxifen out there. I saw one conclusion dated 2004 very preliminary and another published 2014. The conclusion seeming to be for er+ pr- cancers AI drugs level the outcome the same as er+ pr+ on tamoxifen. Remembering that oncodx only looks at tamoxifen use.
I see many people with oncodx scores in the mid range over 20 jumping at chemo. I could see that if they also had a fast growing cancer. And I see people with low oncodx scores with node involvement not getting chemo.
I think it is a useful tool but also consider other information not just the oncodx number.