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Keytruda+Chemo Improves Survival for PD-L1+, TNBC Mets
Adding Keytruda to Chemotherapy Improves Overall Survival in Metastatic, Strongly PD-L1-Positive Triple-Negative Breast Cancer October 5, 2021 Adding the immunotherapy medicine Keytruda to chemotherapy improved overall survival more than chemotherapy alone in people diagnosed with metastatic triple-negative, strongly…
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Experimental Med Vs Drs Choice for Pre-treated Advanced HER2+
Experimental Vic-Trastuzumab Duocarmazine Better Than Doctors' Treatment Choices for Pre-treated Advanced-Stage HER2-Positive Breast Cancer October 5, 2021 The experimental targeted therapy medicine vic-trastuzumab duocarmazine improved progression-free survival and overall survival more than doctors' treatment choice for…
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Kisqali + Femara Ups Survival for Postmeno Advanced HR+ HER2-
Adding Kisqali to Femara Improves Overall Survival for Postmenopausal Women With Advanced-Stage Hormone-Receptor-Positive HER2-Negative Breast Cancer October 5, 2021 Adding Kisqali to Femara as a first treatment for advanced-stage hormone-receptor-positive HER2-negative breast cancer in postmenopausal women improved…
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Podcast: Keytruda+Chemo Improves Survival for PD-L1+, TNBC Mets
Keytruda Added to Chemotherapy Improves Overall Survival for Metastatic PD-L1-Positive, Triple-Negative Breast Cancer September 24, 2021 Dr. Hope Rugo is professor of medicine in the division of hematology and oncology at the University of California San Francisco Helen Diller Family Comprehensive Cancer Center, where she…
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Enhertu Way More Effective Than Kadcyla as 2nd Tx for HER2+ MBC
Enhertu Dramatically More Effective Than Kadcyla as Second Treatment for Metastatic HER2-Positive Breast Cancer September 22, 2021 Enhertu more than doubled the 12-month progression-free survival rate than Kadcyla in people diagnosed with metastatic HER2-positive breast cancer that had been previously treated. Read more...
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Supervised Exercise Safe for People With Bone Metastases
Supervised Exercise Safe for People With Bone Metastases September 20, 2021 People diagnosed with metastatic cancer that has spread to the bones can safely participate in supervised exercise programs, according to a review of 17 studies. Read more...
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Adding Surgery to Tx Plan Offers Better Survival for Some W/ MBC
Adding Surgery to Treatment Plan Offers Better Survival for Certain Women Diagnosed With Stage IV Breast Cancer September 20, 2021 A combination of surgery and systemic therapy can improve survival more than systemic therapy alone for women diagnosed with stage IV breast cancer with known hormone receptor and HER2 status.…
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Tamoxifen side effects
I have been on Tamoxifen for 11 days now and have had pretty severe indigestion from it. Is this a normal side effect? It's very uncomfortable and I take Pantoprazole with added Gaviscon for it but it's not helping at all. I am eating extremely light by the way.
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Soft tissue issue
Hi Everyone, I'm entering into 11 mos post Stage IV diagnosis. I began 7 rounds of Taxotere, Perjeta and Herceptin last December with some Zometa and Zarxio thrown in for good measure 😂 My March scan showed that all liver Mets and bone Mets had healed and I got me a chemo free summer...woot woot! However there is a soft…
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Bayer newly licensed drug called erSO
potential cure of metastatic breast cancer. More information for possible upcoming clinical trials would be appreciated. Google erSO Bayer dru
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Genentech Withdraws Breast Cancer Indication From Tecentriq
Genentech Withdraws Breast Cancer Indication From Tecentriq August 28, 2021 On Aug. 27, 2021, Genentech announced it is voluntarily withdrawing the breast cancer indication from the immunotherapy medicine Tecentriq in the United States. Read more...
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What you wish your friends knew
While you may have been able to educate your close family members about the reality of the disease, you might find that your friends and acquaintances don't quite grasp what you're going through. Have you experienced this? If so, what do you wish your friends and acquaintances knew? Thank you for sharing your insights!
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Is anyone here on Margetuximab (Margenza) without chemo?
Hello, Is anyone here on Margetuximab (Margenza) without chemo for stage IV? Thanks.
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Reaching out for help -11 years in - mets on small intestine
Maybe I should have reached out a while ago, but here I am. I've been, as you can see from my profile, on a lot of treatments. I trust and love my onco. But I've got mets on the outside of small intestine which is causing a blockage that is being very stubborn. Started epirubicin last week. I've been out of work since…
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Alpelisib
Since I had some progression, looks like I will be moving off of Ibrance+fulvestrant. My MO wants me to join a Phase II trial for alpelisib + fulvestrant or letrozole. It is for patients with a PIK3CA mutation, HR+, HER2- who have progressed on or after CDK 4/6 (Ibrance, for example) inhibitor treatment. Wondering if…
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Hormonal Treatment for Stage IV
This thread will be for the discussion of hormonal treatments as they relate to Stage IV members.
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Tried 5 drugs in the lat year, none worked
Hi all, My mother was first diagnosed with breast cancer in Nov 2014 (Grade II, ER+/PR+/HER2-). She did Chemotherapy (Doxorubicin + Cyclophosphamide + Paclitaxel) followed by radiation Then years later she found a lump on her left breast Dec 2019 and had surgery to remove it, after which the Dr said she was stage 1 because…
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FGFR1 amplification
I am asking for collective wisdom for those that have this genetic mutation. FGFR1 amplification is reported to be in 10-27% in breast cancer (per FoundationOne). I progressed after 3+ great years on Ibrance/Letrozole. Recent liver biopsy report from Foundation One(F1) showed FGFR1 amplification and ATM inversion exon 55.…
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Need Your Tips for Members Newly Diagnosed Stage IV
Looking for your tips to share with members who have been newly diagnosed stage IV/metastatic. Being diagnosed with Stage IV/Metastatic disease involves a unique set of concerns. If you could give your newly-diagnosed-with-mets self advice/tips/encouragement, what would you say? Please post in the thread below. We're…
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Stage 4 TNBC NED or Remission
Greetings everyone, I just wanted to know if there are any long term members who are NED or in Remission with TNBC. I was originally diagnosed with stage 3a triple neg. 4 lymph nodes cancerous in 2011. Treatment (Double mast., chemo and radiation) ended in March 2012. Found out I was stage 4 with a lung met in January…
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Lita57
I wanted to start a new thread for Lita, so she will only have to post on one thread. She has received some bad news this week. Let's all come together and walk with her through this. Lita, I posted on another thread that you posted on. Hope this is helpful that now you will only have to post once and everyone will know…
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MBC and Your Job -- whats your story?
We're looking for submissions about your experiences with a metastatic breast cancer diagnosis and managing your career. Did you find great support in the workplace from your employer and colleagues? Did you feel comfortable disclosing your diagnosis? Were there any unexpected reactions? How did you handle any…
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Please Read! Check Vit. D, 25-Hydroxy Levels
New research suggests that breast cancer patients with high levels of the vitamin in their blood are twice as likely to survive the disease than patients with low levels... The studies included a total of 4,443 patients with breast cancer and were performed between 1966 and 2010. All patients were followed for an average…
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For those on Ibrance, PFIZER Oncology Together can provide help
Pfizer Oncology Together is a first-of-its-kind program for patients taking Pfizer Oncology medicines that offers dedicated social workers called 'Care Champions' to help navigate the complexities that accompany treatment, such as identifying resources to help find emotional support, and workplace transition,…
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Is the Highest Dose Always the Right Dose for Us?
You may be interested in this article about a patient advocate-led survey which was presented in June at ASCO 2021. It's seen as the "first step" in determining whether there may be a different approach to treatment where people affected by metastatic breast cancer and their doctors collaboratively discuss the best dose…
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Black voices needed! Help make metastatic breast cancer research
Black voices needed! Help make metastatic breast cancer research more diverse by taking an anonymous patient survey about your thoughts on clinical trials (even if you've never participated in one). Survey closes July 15th. Go HERE to start the survey!
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Most W/ MBC Have Troubling SEs, Willing To Discuss Dosing
Most Women With Metastatic Breast Cancer Have Troubling Treatment Side Effects, Willing To Discuss Dosing Options With Doctor June 16, 2021 About 86% of women diagnosed with metastatic breast cancer had at least one bad treatment-related side effect, and 92% were willing to discuss options for different dosing levels of…
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Lets Talk About Oncologists
What do you look for in an oncologist? What is it about your onc that you like? Why I ask: My oncologist and her nurse are retiring soon. They've been with me for 10 years since I was first diagnosed. I got kinda spoiled, they were so good to work with in so many ways and I will miss them immensely. They are both over 70…
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Tukysa + Standard Tx Improves Survival in Advanced HER2+
Adding Tukysa to Standard of Care Continues To Improve Survival in Advanced-Stage HER2-Positive Breast Cancer June 15, 2021 Adding Tukysa to the standard of care of Herceptin and Xeloda continued to improve both progression-free and overall survival in people diagnosed with either metastatic or unresectable locally…
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Kisqali-Faslodex Combo Improves Overall Survival in Advanced HR+
Kisqali-Faslodex Combo Continues To Improve Overall Survival in Advanced-Stage, Hormone-Receptor-Positive Breast Cancer in Postmenopausal Women June 20, 2021 The latest results from the MONALEESA-3 study show that combining Kisqali plus Faslodex continues to offer better overall survival than Faslodex alone. Read more...