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Podcast: Hope After a Triple-Negative Diagnosis
Thought you all might be interested in this podcast from Breastcancer.org: Hope After a Triple-Negative Breast Cancer Diagnosis Hope you find this helpful! -- The Mods
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Tumor oscillating in size during chemo
Hi all! I have been diagnosed in early August with TNBC 30mm stage 2, grade 3, no lymph node involvement. I am negative for all 132 gene mutations, PD-L1 positive and TILS positive. I also had an 8mm spiculated nodule on one of my lungs that didn`t show activity on PET SCAN and was dismissed as scar..that still worries me.…
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Androgen Receptor Positive TNBC
Has anyone had their tumor tested for AR? I had a very poor response to neoadjuvent chemotherapy, which was a surprise because I had a complete clinical response, and am pretty young- which are both usually indicative of a good response to chemotherapy. I have been making rounds on second opinions since getting my surgical…
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Nivolumab - anyone tried this immunotherapy?
I was on keytruda during my chemo (AC-T) but had to stop after 2 doses due to a prolonged fever and elevated heart rate, which apparently is a rare side effect. Now I'm done with chemo and radiation, my Onc wants me to try another PD-1 immunotherapy drug called Nivolumab. I see it's not yet FDA approved for breast cancer,…
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Carboplatin-Taxol + Keytruda - Thread to Share Your Experience
Hi Everyone, Next week I will start a 24-week regimen of weekly Carboplatin/Taxol with Keytruda once every 3 weeks for 12 weeks. I understand this is the newest protocol for TNBC, so I thought it might be good to start a thread. I look forward to the chance for all of us to learn from one another! Aleta
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TNC metastasis to jaw?
Hi all. My dentist today found a strange spot in my left jaw. I'm going to have an oral surgeon look at it Monday. Anyone have triple negative BC metastasis to jaw?
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Immunotherapy Med Works Similarly in Black/White Women W/ TNBC
Experimental Immunotherapy Medicine Works Similarly in Black and White Women With Triple-Negative Breast Cancer Aug 4, 2022 When more Black women diagnosed with early-stage, triple-negative breast cancer joined a study on Imfinzi, the results showed the immunotherapy was as effective in Black women as it was in women of…
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Enhertu Improves Survival in People With HER2-Low MBC
A New Standard of Care? Enhertu Improves Survival in People With Metastatic HER2-Low Breast Cancer June 6, 2022 Compared with doctors' choice of chemotherapy, Enhertu (chemical name: fam-trastuzumab-deruxtecan-nxki) improved both progression-free survival and overall survival in people diagnosed with previously treated…
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Keytruda q3 wks and now elevated liver enzymes
I went through all the chemo for tnbc and finished in Nov 2021. Got the PCR and had a lumpectomy in Dec. Radiation for 20 sessions just to be safe. I started with Keytruda when I was on taxol/carbo and have continued Keytruda every three after surgery. My enzymes were slightly elevated last time but I still got the…
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Lynparza Approved To Treat High-Risk, Early-Stage, HER2-, BRCA+
Lynparza Approved To Treat High-Risk, Early-Stage, HER2-Negative Breast Cancer With BRCA Mutation Mar 13, 2022 The FDA approved Lynparza to treat early-stage, HER2-negative breast cancer with a BRCA1 or BRCA2 mutation and a high risk of recurrence, which also has been previously treated with chemotherapy — either before or…
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Sentinel Node Biopsy
Hello all, My wife was recently diagnosed with TNBC and upon scans it showed that her tumor was roughly 5cm. She did a PET, Bone and MRI. The drs said that the scans showed no cancer in the lymph nodes. Everywhere I am reading I see that people get a sentinel node biopsy as well to determine whether the nodes were…
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Hi, new and just diagnosed with TN
I’m in shock mainly because I’m 56 and have been on estrogen and progesterone since 2016 so when they first saw something I was sure it was the hormones! It seems to strike the younger more often. Anyone else this age when diagnosed? We are still waiting for the PDL-1 results. Mt KI-67 is 54% and my mass is 2.4 cm and…
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Looking for members experience
Hi! I'm new on this forum and I'm curruntly interested in Triple Negative Breast Cancer topic, since I'm studying it for an exam. I'm looking for some informations or personal experiences about it, if someone is willing to share. Thank you
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Surgery before chemo
Hi lovely ladies, Just wondering if any of you with TNBC had surgery prior to chemo? I know it’s protocol now to have surgery before chemo but I have also seen some stories were surgery was performedbefore and the ladies are doing fine. It seems a bit counter-intuitive to me. What do you guys think?
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Hey calling all Node positve survivors
Hi Everyone, Well I finished the last of my clinical trial on Nov 10 and today is exactly one year ago that I recieved that "call"...."I'm sorry but its cancer". I'm feeling very emotional about the last year and what is to come. I'm scared. I am hoping to get some positive feedback from some of you long term…
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Im devastated, terrified and angry! Newly diagnosed.
I can't believe I have to write this. I am 36 years old and was diagnosed with triple negative stage IIB invasive ductal carcinoma, just last week. To say I am terrified is an understatement. My treatment team says news research has showed for this kind of cancer, to do chemotherapy and immune therapy, first is standard.…
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Keytruda (pembrolizumab) Experience
****Breastcancer.org Moderators have approved this posting. Please note that Breastcancer.org is NOT responsible for, and is not endorsing any studies.**** My name of MJ DeCoteau and I am the executive director of Rethink Breast Cancer (www.rethinkbreastcancer.com) – a Canadian patient group dedicated to building community…
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Anyone know about the red devil?
I’m about to start chemo for triple negative breast cancer and that’s one of the drug
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Share Your TNBC Story
Hello, everyone! Share your triple-negative breast cancer story here to give hope to others recently diagnosed.Thank you for contributing! --The Mods
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Podcast: Keytruda+Chemo Improves Survival for PD-L1+, TNBC Mets
Keytruda Added to Chemotherapy Improves Overall Survival for Metastatic PD-L1-Positive, Triple-Negative Breast Cancer September 24, 2021 Dr. Hope Rugo is professor of medicine in the division of hematology and oncology at the University of California San Francisco Helen Diller Family Comprehensive Cancer Center, where she…
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Carboplatin + Chemo Before Sx Improves Early TNBC Outcomes
Adding Carboplatin to Chemotherapy Before Surgery Improves Early-Stage Triple-Negative Breast Cancer Outcomes September 20, 2021 Adding carboplatin (brand name: Paraplatin) to the standard neoadjuvant chemotherapy regimen for early-stage triple-negative breast cancer improved event-free survival. Read more...
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Just diagnosed with Triple-Negative--so many questions...
Hello everyone, So I had a stereotactic core biopsy of the left on 7/1/2021. Results: Benign breast tissue showing fibrocystic change and focal fibroadenomatous changes. On the same day, 7/1/21, I had sonogram guided core biopsies of two locations on the right. Well, both locations on the right side are Invasive ductal…
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FDA Approves Keytruda for Early-Stage TNBC
FDA Approves Keytruda for Early-Stage Triple-Negative Breast Cancer July 27, 2021 The U.S. Food and Drug Administration (FDA) has approved Keytruda plus chemotherapy before surgery, followed by Keytruda alone after surgery to treat early-stage triple-negative breast cancer with a high risk of recurrence. Read more...
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Keytruda Before & After Sx Improves Outcomes in Early TNBC
Keytruda Before and After Surgery Improves Outcomes in Early-Stage Triple-Negative Breast Cancer July 27, 2021 The immunotherapy medicine Keytruda plus chemotherapy before surgery and Keytruda alone after surgery improved event-free survival better than chemotherapy alone in women diagnosed with early-stage triple-negative…
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TNBC w/significant lymph node involvement
MO just informed me yesterday that the lymph node biopsy showed positive for the breast cancer. Stated that the treatment would be different than previously planned. No surgery or radiation and Abroxane (chemo). Said that I would be in chemo for the rest of my life. I was too shocked to ask questions. Anyone been through…
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Minimally Hormone Receptive
Hi! My cancer is technically ER+/PR+ however the hormone levels are minimal— 2% and 1% respectively. The MO wants to treat the cancer as if it were triple negative— with chemo. I am BRCA1 positive and small tumor. I had a BMX, the nodes came back clean and I was classified as Stage IA. Oncotype was not done but she's…
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Anyone have TNBC with lobular diagnosis .
I have been diagnosed with Lobular TNBC. My Dr says this is ver rare still . Treatment protocols ? Trials . Any one experience this ? thanks Susan
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Lynparza Offers Benefits for Early-Stage HER2- BRCA+
Lynparza Offers Benefits for Early-Stage HER2-Negative Breast Cancer With BRCA1/2 Mutation June 10, 2021 Adding Lynparza to standard treatment for early-stage HER2-negative breast cancer with a high risk of recurrence in people with a BRCA1 or BRCA2 mutation improved disease-free survival. Read more...
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Just diagnosed with triple negative breast cancer
Hi guys! So I was diagnosed with breast cancer in my lymph nodes on February 19th. With further testing they did find a tumor in my breast and I have a biopsy scheduled for next Monday. It is measuring 5cm. Isn’t that kind of big for not showing up on a mammogram? The cancer in my lymph nodes is triple negative. I feel…
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New group member
Just got informed today that my weakly ER+ (5%) has been classified as negative so I am officially part of your group. Nice to meet you all and wishing you all good outcomes. For other newbies I know this can be a very scary experience. I myself am frightened. I just keep picturing myself with a cap over my head, skinny &…