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Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer?
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Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer?
Dec 6, 2024
Dr. Donald McDonnell discusses his research on estrogen, eosinophils, and triple-negative breast cancer.
New research suggests that estrogen plays a role in allowing hormone receptor-negative breast cancer to grow. This is because estrogen limits the ability of the immune system to attack cancer cells; it also makes immunotherapy medicines, like Keytruda (chemical name: pembrolizumab), less effective. Dr. Donald McDonnell, senior author of the study, explains the results and how they might make a difference for people with breast cancer.
Listen to the episode to hear Dr. McDonnell explain:
- what eosinophils are and how he started studying them in connection with breast cancer
- how estrogen in the body affects the immune system
- how a hormonal therapy medicine, like tamoxifen, can make an immunotherapy medicine, like Keytruda, more effective
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