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Triple-Negative Breast Cancer Treatment: Where Are We?
Triple-Negative Breast Cancer Treatment: Where Are We? Dr. Lisa Carey explains the latest research on TNBC treatments. Mar 7, 2025 About 10% to 15% of breast cancers are triple-negative. This means they don’t have receptors for the hormones estrogen or progesterone, and don’t have too many HER2 proteins. So, hormonal…
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Helpful links about Triple-Negative Breast Cancer
For more information, see Breastcancer.org's Triple-Negative Breast Cancer section. Check out this Podcast: Hope After a Triple-Negative Breast Cancer diagnosis. Triple-Negative Breast Cancer Stories Hope this helps! --The Mods
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Calling all TNs
I think that we tn's need to have a sign up list like some of the other threads have...maybe put your age, and also what treatment you have had or are now having. What to do you think? I can start: age 50, diagnosed at age 49 1/2, lumpectomy, 4 AC Dose dense (every two weeks) and 4 Taxol, Dose Dense every 2 weeks. 35 rads…
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Reconstruction options
My wife has finished six months of chemo and immunotherapy and scheduled for a mastectomy at the end of the month, to be followed by up to six weeks radiation. We have discussed reconstruction with both the primary surgeon and a plastic surgeon. Quite frankly, these have been good discussions, but we still feel confused as…
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Triple negative 4mm - No chemio?
please help I have a TNBC, 4mm. My doc said no chemio but I am so so afraid. Please, could smb share an Experience? Please help, I need help
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Sacituzumab Govitecan (Trodelvy)
Hello everyone. I was wondering if anyone(s) could share any experiences they have had using sacituzumab govitecan (Trodelvy) either in a clinical trial or as recently approved by the FDA. We are trying to determine if it's the best plan of action for my wife at this time. There are 2 key things we are trying to determine.…
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TRIPLE NEGATIVE (Age 74) Lumpectomy (twice) ONE positive sentinel node - REFUSING TREATMENT
Good day, I'm writing on behalf of my 74 year old mother. She was diagnosed February 2023 with Invasive Ductal Carcinoma and Ductal Carcinoma In Situ (IDC & DCIS). Triple negative was our diagnosis. Ki67 is 20-25%, Grade 2, Apocrine features. First lumpectomy - (March 2023) clear margins, one out of six sentinel lymph…
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Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer?
Can Hormonal Therapy Help Treat Triple-Negative Breast Cancer? Dec 6, 2024 Dr. Donald McDonnell discusses his research on estrogen, eosinophils, and triple-negative breast cancer. New research suggests that estrogen plays a role in allowing hormone receptor-negative breast cancer to grow. This is because estrogen limits…
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Calling all triple negative breast cancer patients in the UK
With so many forums and threads on this site to go through for information, I thought it would be a good idea for all of us in the UK to form a forum specifically for us, and to give our details and experiences in a compact manner. Anyone else in the world is welcome to join in. I was diagnosed with a very large tumour,…
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Symptoms before being diagnosed
I wanted to see what symptoms did you all get from breast cancer before you were diagnosed as there are hardly any when you look them up but have noticed I got different ones in the time period I started noticing the lumps. I had and still have tiredness, indigestion, loss of appetite and loss of weight.
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Long term survivor examples.
Just an idea came across my mind. Can we share stories and examples of long term triple negative survivors. They dont participate in such forums. So its only by word of mouth that we get to hear about them. But I also see few of them in this website, who themselves are long term survivors. I feel so happy to see how they…
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Keytruda Improves Survival in Triple-Negative Breast Cancer
Keytruda Improves Survival in Triple-Negative Breast Cancer September 15, 2024 People diagnosed with early-stage triple-negative breast cancer who received the immunotherapy Keytruda (chemical name: pembrolizumab) along with chemotherapy before and after surgery had better event-free survival — how long they lived without…
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Keytruda Adverse Event and Rechallenge
Hello fellow TNBCers, I am reaching out for help regarding a situation I am in. I was recently diagnosed with TNBC back in January 2024. Invasive Ductal Carcinoma, Stage 2B (maybe A, 4x lymph nodes lit up on my petscan, but the axillary node which was biopsied 2x, one as FNA and a repeat with a core needle, both came back…
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To the newly diagnosed: 6 Years With TNBC, Still Going Strong
Good morning, everyone. I’m stopping in after a long hiatus to offer some help to those newly diagnosed with TNBC. Almost 6 years ago I was diagnosed with stage 3C triple negative breast cancer. I was in total shock, grief, and had to stop working due to anxiety and depression. I have had two recurrences since then. I am…
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More Immune Cells in Triple-Negative Breast Cancer May Mean Lower Recurrence Risk
More Immune Cells in Triple-Negative Breast Cancer May Mean Lower Recurrence Risk Apr 24, 2024 Higher numbers of certain white blood cells in a tumor may mean triple-negative breast cancer is less likely to come back. Read more…
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Triple-Negative Breast Cancer Has Unique Risk Factors
Triple-Negative Breast Cancer Has Unique Risk Factors Apr 23, 2024 Being older when having your first child and breastfeeding seem to offer some protection against triple-negative breast cancer. Read more…
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TNBC reoccurrence in treatment (Xeloda & Proton Therapy)
Hi 😊I am dealing with my 2nd reoccurrence of TNBC and currently in treatment. Starting my 4th week of Xeloda M-F (1000mg twice a day) also doing Proton Therapy. Have 20 more treatments. My oncologist said I will continue with the Xeloda after my Proton Therapy is completed. Has anyone gone thru the same treatment as me?…
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Neoadjuvant EC Regimen precautions
Posting this on behalf of my wife (aged 34) who had been diagnosed with TNBC in October 2023. She had recently completed her weekly 12 sessions of TC regimen : Paclitaxel (120mg) and Carboplatin (200mg). Although there was Hair Loss and slight nail discoloration from 3rd week onwards, she had Nausea from Day 1-4 post every…
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In Triple-Negative Breast Cancer, Response to Chemotherapy Before Surgery Varies by Race and Ethnici
In Triple-Negative Breast Cancer, Response to Chemotherapy Before Surgery Varies by Race and Ethnicity Apr 8, 2024 After chemotherapy before surgery for triple-negative breast cancer, Black women are less likely and Hispanic women are more likely than white women to have a pathologic complete response. Read more…
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Moved: Battling triple-negative, non-hormone-sensitive metastatic breast cancer
This discussion has been moved.
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TNBC Survivorship plan
I was diagnosed with TNBC in July 2022. I had a lumpectomy in August, then chemo Oct-Dec. Because of the genetics results, I elected to have a bilateral mastectomy with breast reconstruction using my own abdominal fat in January 2023. I have recovered quite well. By April 2023, my med onc discharged me to family practice,…
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Triple Negative Breast Cancer
Anyone else in the UK had TNBC and gone on to have HRT or oestrogen creams ? There seems to be a lack of knowledge with GP's. Any info would be grateful. Just out of interest I'm also had surgery for hyperparathyroidism.
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Experience with Keytruda for early stage Triple Negative Breast Cancer
Hi Since the standard of care for early TNBC has changed and now includes Keytruda (Pembrolizumab) with chemotherapy in the neoadjuvant setting, followed by Keytruda alone for 9 cycles in the adjuvant setting, I was wondering if everyone on the current regimen could share their experiences? How has it affected you? Have…
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Stage 3/4 TNBC - delays in BC, Canada
Hello, I’m curious what the community here has experienced in terms of time from diagnosis to start of treatment. I am concerned about accessing treatment and delays where I live. Dec 9, 2023: found lump Jan 19, 2024: ultrasound and xray, suspicious Feb 1, 2024: core needle biopsy, clip inserted, additional ultrasound and…
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Stage III TNBC. Looking for stories of hope
Hi. My 30 year old wife's been diagnosed with TNBC. Unfortunately our treatment right from the start has not gone as per the standard algorithm. In fact her 4cm lump was determined to be a fibroadenoma and excised by a general surgeon, and it turned out to be tnbc with LVI, ki-67 65-70%, necrosis present, closest margin…
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Triple negative and oestrogen positive
Hi all, I am hoping someone can help. I was diagnosed with invasive, aggressive, triple negative breast cancer in May 2023 with some micrometastasis in 3 out of 4 lymph nodes. Have had surgery, chemo and radiation therapy. Apparently 5% of the cancer was oestrogen positive and my oncologist if leaving the option to take…
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Newly Diagnosed Triple Negative
Wow the last month has been a whirlwind. Dx on 12/19 with TN Stage I with no lymph node involvement. Mastectomy with reconstruction is scheduled for 2/27 and discussions of post op chemo have started… I feel so overwhelmed with the unknown. please share any tips, insight or wisdom!
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Sister just diagnosed with TNBC
Good morning, everyone, My sister was just diagnosed with TNBC, in fact she hasn't been staged yet but the Onc feels she's probably at IIIB given the size and at least one Node involvement. She will be getting her scans this coming week then starting Chemo. She lives in Georgia and I'm in PA so I can be at her dr appts to…
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Triple Negative Treatment Plan
I’m finishing up NAC chemo 4 rounds of a/c, 6 rounds of Tchp, to be followed by a double mastectomy and rads. Did any of you have chemo after your surgery/rads? I know it depends on the results of the surgery pathology report but just trying to get a handle on what is to come. Could you share your experiences?
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TNBC for my Birthday! Scared and Confused.
I've been searching everywhere to find a peer to peer group, to maybe find someone who has been diagnosed with my same form of breast cancer as I figure out what treatment path to take. I was diagnosed with TNBC on September 18th. I have since been on a whirlwind ride of getting doctors to respond etc. Here are my details:…
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Breast Cancer Vaccine Update
Breast Cancer Vaccine Update Dec 7, 2023 Dr. Justin Johnson explains early results from three small studies on a vaccine for triple-negative breast cancer. Dr. G. Thomas Budd, an oncologist, and Dr. Justin Johnson, an immunologist, are collaborating on research looking at a vaccine to prevent triple-negative breast cancer.…
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Stage 2 triple negative breast cancer
I was diagnosed with stage 2 triple negative breast cancer. Because my tumor is aggressive and fast growing they flipped the treatment around from doing surgery first and starting chemo instead. I have made my decision from the choices I was giving which basically was double mastectomy followed by reconstructive surgery. I…