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Anyone on just Taxotere and Cytoxan?

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  • otter
    otter Member Posts: 757
    edited July 2008

    Hi, gang!  I've added SherriM to our TC list.  She's having the first of 4 rounds of TC on July 10.

    Oh, yeah--does anybody know why I'm getting fluid retention and swelling now, 4 weeks after my last dose of Taxotere & Cytoxan???  It's especially noticeable in my lower legs and ankles, but my fingers are kind of puffy too.   I'm thinking this is why my mast incision and chest wall have been bothering me for the past week.  This has come on gradually, ever since about day 21 of tx #4 (i.e., last Wednesday).

    I'm wondering if this was happening, or would have happened, with the other tx's, but it was being kept in check by the Decadron.  That's one of the things Decadron (dexamethasone) is supposed to do--it's supposed to inhibit allergic reactions to the Taxotere, but it's also supposed to reduce the fluid retention Taxotere causes.  I read that in the on-line packaging info and in some articles in medical journals.  I thought the fluid retention would be an early SE, though--I never imagined it was something that would occur so late in the treatment cycle, or even after treatment had ended!

    I don't know how often this late edema occurs, or how long it will last.  I've read some things about women being given diuretics, like lasix, for edema, but I don't want to go there.  My bp is low anyway.  The swelling isn't severe, but it sure wasn't something I was expecting. 

    otter 

  • collector
    collector Member Posts: 72
    edited July 2008

    Otter, your edema sounds mysterious and aren't you planning a trip sometime soon?  I have been getting the Decadron with the treatments too and have just been getting some swelling in my hands after this third treatment on Monday.  I take the decatron for 3 days after the infusion in pill form.  Sure seems like Taxotee might be the gift that keeps on giving. 

  • Stickerlady
    Stickerlady Member Posts: 1
    edited July 2008

    I had my second TC yesterday and after a few minnutes I had stomach pain, then my back hurt and I turned bright  red from my chest up and had a hard time breathing. They turned the Taxatore off right away and gave me something in the I.V. and after about a half hour or 45 mins they started it up again and it was O.K. Boy was that scary. The Dr. gave me the purple pill for acid reflux this time and boy what a difference. She also changed my pain meds to Oxycodone instead of Vicodine because the Vicodine didn't work so good first ime for the pain that settles in on day 5 or 6. It is from the WBC shot I get the day after. My RBC is very low and she gave me Iron pills for that and if it gets worse she will give me a shot next time for that. Hope everyone is doing O.K. I am now half way done. Only 2 more and then 6 weeks of Radiation.I live in Alaska and my parents are sending me plane tickets to spend a month in Myrtle Beach S.C this winter and that is what is keeping me going. My sister lives there and my parents stay there winters so we are going to have a wonderful time together.

  • robink
    robink Member Posts: 60
    edited July 2008

    Gee Otter,

    Edema now? when things should be going away.  Somewhere (i don't know if it was on this thread) in some information about Taxotere I read about peripheral edema/taxotere and either occuring a while after treatment concludes or the possiblity of lasting quite a while in some persons.

    After treatment #3 on day 7-9ish I developed edema of my hands, feet, lower legs, and mast. site.  Today I mentioned it to my onco who agreed it was from the Taxoteres.  He said if it happened in round #4 and didn't self resolve OR was worse than last time he would prescribe a diuretic.

    Tomorrow is the beginning of the end for me...last chemo!  It will be more of an end 3 wks after my last trip to the chemo bar and I receive my final labs and my walking papers!  Oh yeah, and I suppose a prescription for an aromatase inhibitor.

  • Tigwin
    Tigwin Member Posts: 115
    edited July 2008

    Otter...are you getting some exercise and drinking a lot of water??  It is pretty hot lately and seems like I need to move a bit more and drink a bit more...put your feet up and drink some H20...good luck

  • beergirl
    beergirl Member Posts: 83
    edited July 2008

    Otter, I agree with Tigwin. Drinking water and walking seem to help at lot with most everything. I had tx #3 today and before I got on the computer I was feeling a little puffy about my face and neck. They don't look puffy though, but my fingers do. Maybe that will go away by morning.

  • otter
    otter Member Posts: 757
    edited July 2008

    Hi, all-- 

    The edema really isn't bad--it's just that normally my ankles and the bones in my hands are very visible, and now they're not.  But it comes and goes, which is probably a good thing (better than staying puffy all the time...).

    I had cut out most salty foods during chemo anyway, so I'm back to doing that and being even more careful now; plus I'm trying to drink more water (thanks for the reminder!).  Also, Tigwin and Beergirl, you're right about the activity level.  I've become a lazy slug, and I really need to get moving around more.  I'm keeping my feet up when I'm not moving around, which seems to help.

    I haven't done a literature search yet, because I was in a no-internet zone for the past 24 hrs or so, but I'll check on the late-onset edema.  I'm pretty sure it's the Taxotere (what isn't???), and, like you, I know I read some reports about it here on the boards.  Sounds like all my onco would do is put me on a diruetic, and I know for sure it's not that bad.  (Been there, done that, for other things.)  Thanks a bunch for the suggestions.

    Today I was supposed to be having a DEXA bone density scan, but I got a call this morning that they had to cancel it because the tech had a family emergency.

    Robin, Debbiem425, ggrose, judianna, rogam (who is usually over on the African American board), and BBLady, have a smooth infusion today.  We don't want any of those reactions like Stickerlady had.  That's too scary.  And, beergirl, your tx was yesterday and not today?  I had the date wrong in our TC calendar.  Sorry!

    (Confession:  My dh and I spent the past 2-1/2 days on our boat, so I'm kind of out of touch with reality at the moment.  We're heading home in a few hours, instead of heading for the cancer center for my DEXA scan.  I just called them, and it has been rescheduled for next Wednesday.)

    otter 

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Don't mean to change the subject, but ITCHY ITCHY ITCHY!!  I'm on day 8 of tx 2, and I was minding my own business this morning, when first my head started itching like crazy, and actually throbbing where redness & bumps were popping up.....now in addition I have very itchy hives on the back of my knees and neck, and I think between my shoulder blades.  ARGGH!  I have hydrocortisone cream and oral Benadryl.....has anyone tried anything that works better?  I also rubbed Neosporin on my head (about 1/8" long hair now).  I feel like plunging my itchy head into the swimming pool and letting the chlorine burn the itch away.  (I know, a stupid idea.  I won't.)  I have to go out to eat tonight and I can't imagine how I'll stand a hat or anything on my horribly itchy head!  Help?  I may jump out a window from itch-induced insanity.  Good thing my house is only one story.

    Otter, I'm glad you got a little getaway on your boat--what fun!  We're leaving Sunday for a week at the beach and I'm hoping & praying I don't have major s/e's while we're gone.  These hives are quite attractive while wearing summer clothes.....

  • lalani
    lalani Member Posts: 3
    edited July 2008

    i start on july-11th. feeling nervous about what to expect-side effects-pain. i have spinal arthritis. anyone feel that treatments made this worse?

    first oncologist was going to have me have a port but, this one says a pic which i go in for on thursday.

    also, since i am having treatment on a friday i am a little nervous about it being the weekend. guess if anything happens there are two onc. on call at the hospital.

  • slortiz
    slortiz Member Posts: 142
    edited July 2008

    Checking in:  Day 8, Tx 1

    Well, I was doing pretty well, but labs drawn on Tues (Day 5) returned as perilously low re WBC (WBC< 1000, Neutrophils <500) even though I had had a Neulasta shot on Day 2. The Onco called and told me to come into the office the next morning and to high-tail it to the ER at any sign of infection. He scared the bejesus out of us, and I just didn't get it, since I felt pretty well. Then, when he saw me the next morning, he seemed relived as I was obviously looking pretty good, with only slightly elevated temp. Nevertheless he gave me a Rx for Levaquin to take prophylactically for a week. Cripes. My whole life I've managed to escape taking anti-biotics, and I attribute my good health to that fact. Now within the past few months I've been dosed twice with two of the biggest guns, Cipro and Levaquin. Not happy. I can just picture the Super Bugs that are going to start evolving in my body because of this. Damned doctors.

    The Neulasta finally kicked in last night with regard to bone pain. My question is this. I opted to get the Neulasta shot in my tummy, and I'm wondering if this slowed down its entry into the bone marrow, vs taking it in the arm?  The Onco said no, but I wondered if there's been any discussion of this. (Sorry, I'm just too tired to search through 79 pages of commentary)  I'm depressed about the low WBC with the very first treatment as I thought this problem didn't kick in until later in the regimen. Seriously doubt this chemo is worth the trouble and risk for me. It's different for you younger gals. I sat down and did the math. At age 65 I have a 22% chance of dying in 10 years from some kind of cancer and a 15.2% chance of dying from something else. Doing the chemo (in addition to the hormones) improves this picture by 5.5%, from 31.3% from all causes to 25.8% (per Adjuvant! Online). The TAILOR-X people would have you believe that doing the chemo is going to reduce your risk of death by 30% if you have a hi score for recurrence (mine was 29), but that's really only true for younger people with regard to their risk from cancer. In my case, it will reduce my overall risk of dying in ten years by 17%. (5.5% as a percentage of 31.3%) And I'm not even sure it's that beneficial, since I suspect the chemo increases your risk of dying from "other causes." Do I just have to roll over for this because?

    Can you tell I'm depressed?

  • robink
    robink Member Posts: 60
    edited July 2008

    HAPPY LAST DAY OF CHEMO TO ME!

    A few of the nurses gathered round me and sand to me, gave me a card and a lovely mug with sunflowers.  I am touched...I am also glad to not have to come back here!

    As I write this I am still in the chair, getting Zofran now then Cytoxin then HOME!  To the rest of you finishing today CONGRATS!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!  I will consider myself officially done when my 3week post chemo labs are drawn and comback normal.

    To all a good July 4th weekend and minimal SE to those in need.

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Congrats to you Robin!

    Has anyone tried using Tea Tree Oil to help with the itchy scalp/bumps?  If so, full strength or diluted?  It smells fierce, but if it'll help....

    Thanks~

  • beachmom13
    beachmom13 Member Posts: 85
    edited July 2008

    Congrats Robin.  Isn't it a great feeling? I'm sure you'll breeze through the last ses.

    Catlover44 - my dh uses tea tree oil full strength.  Yes, she does stink, but the bumps are usually gone the next morning.  The day after at the latest.

    Lee

  • otter
    otter Member Posts: 757
    edited July 2008

    Way to go, Robin!!!!

    Sandra (sloritz), that Neulasta shot probably kept you out of the hospital.  The injection needs to be given subcutaneously, so it is possible that it didn't end up there if given in the tummy.  No offense or assumptions, but if they had tried to give it in my tummy, it could very easily have ended up in fat tissue where it wouldn't have been absorbed effectively.  All 4 of mine were in the back of my arm, and they didn't hurt a bit (until a few days later of course).  As for the low wbc with your first tx, I've done quite a bit of reading about Neulasta, Neupogen, and the effects of chemo on the wbc (neutrophils specifically).  From what I've read, bone marrow generally takes the hardest hit from the first chemo tx, as long as you're getting "support" from Neulasta or Neupogen.  I've seen graphs of wbc over 4 chemo tx's (Adriamycin and Taxotere, I think it was) with Neulasta or Neupogen, and the lowest wbc's were during tx #1.  That said, the only tx's in which I developed a fever and needed antibiotics were tx #3 & 4. 

    catlover44, what a coincidence!  The only time I developed hives was during my 2nd TC tx, although I got them earlier than you did.  Mine came around day 3 and were gone by day 6. OTOH, I also developed red bumps on my scalp around day 8 or 9 of tx #2.  They "matured" into pustules but were gone by the time of my next tx.  I never got them again.

    For me, the key to resolving the scalp bumps (I kindly called it a "rash" but it didn't look rash-like) was switching from my regular shampoo ("Finesse") to J&J baby shampoo.  I tried an antibacterial soap one day, but that was disastrous--really irritating to my already-tender skin.  I also tried Head & Shoulders shampoo one time, but that didn't help either.  In fact, my onco and her nurse both said the antibacterial soap and the Head & Shoulders probably made things worse.  They urged me to use something very mild, like baby shampoo, or even "Neutrogena" face soap.  I stuck with the J&J baby shampoo on a daily basis, and the bumps dried up and went away, never to return.  I'm still using it, 4 wks after my last tx.

    I have been threatening to post pics of some of my more prominent TC SE's, like the scalp bumps and my sore feet.  I'll try to get to that tomorrow.  I think it might be helpful if we can share details about stuff like that.

    otter 

  • VBG
    VBG Member Posts: 75
    edited July 2008

    Hi All,

    Well as I mentioned "Bald' happened  all at once when I washed and combed my hair on Tuesday.  I took my wig "out for a test drive" and got lot of compliments on my new haircut!!!

    We I had my second TX yesterday and all went well.  I am feeling really good, not too tired, no nausea and so far no other SEs.  I am using my saline mist starting now instead of waiting for my nose to dry out!  All my blood work came back great!

    I am feeling very lucky and now a bit less stressed that the hiar thing has finally happened! 

    How long after hair fall out do eyebrows and lashes go!

    Wishing you all a great night!

    Valerie 

  • SusanDL123
    SusanDL123 Member Posts: 21
    edited July 2008

    Hi,

    In answer to your question, yes I think you're depressed.  Not without reason, however.  We are all struggling more or less at different times.  But, I must take issue with you being "old" and basically not worth it.  I am also "old".  63 and counting.  There is no way that I am going to sit down and let the numbers game beat me down.  My oncodx score was 40. Frighteningly high. But what I tell myself is that only a couple of years ago, there was no oncodx score and I wouldn't have known I was at greater risk for recurrence.  According to my Dr. Onc., doing chemo (which I was told originally by the surgeon I wouldn't need) cuts my risk of dying in 10 years by half.  I'll take those odds even though I feel like shit and as if I have a nice case of the flu.  (Tx 3  Day 3).  I am expecting a new grandchild any day and I want to be around for a very long time to watch him or her grow up.  Hang in there.  We will get through this. 

    Susan 

  • Debbiem425
    Debbiem425 Member Posts: 27
    edited July 2008

    HI everyone

    I was scheduled for #3 today but got a call Tuesday asking me to switch and come in Wednesday.  I guess they were expecting a crazy day today.  My office said that was fine so I went ahead and got it over with.  Went back for my shot today.  I worked a half day today, did some errands on the way to get my shot, then came home and took a nap.  I am pretty tired tonight.  Tomorrow the place I got my wig is actually open so I am treating myself and taking it there for a wash and blow dry so I don't have to do it. Cheaper then a haircut :)

    I don't use shampoo on my head, I have just been using the same soap I use for my body.

    VBG I haven't lost any of  my eyelashes or eyebrows.

    Otter - good for you getting away for a couple of days on the boat!  Last Friday night we went out on a friends boat.  I was a little nervous because I wore my wig but it stayed on perfectly.  I am so used to it now, I pop it on so quickly and hardly feel it during the day - but it does come off pretty quickly when I get home.

    Anyone have a teeny head?  I ordered three BeauBeau's and by mistake ordered one in an extra small.  I would be happy to send it to someone, it's a blue print.  It was on sale so I couldn't exchange it.

    Happy 4th everyone!

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Otter, thanks for the hopeful words about these $^#&$ hives!  Everywhere I have them, it feels like when you have a bad sunburn that actually hurts down to the muscles & nerves.  It was a long night!  I did tea tree oil yesterday and it helped temporarily.  I'm trying not to stink everyone out today with it, so I put hydrocortisone everywhere this time.  I'm really glad to hear the hives didn't come back after that one time for you.  Of course, today being a holiday, I'm running a little fever--my first one.  It's just 99.8 and I'm going to keep checking it.  I'm really starting to second-guess going out of town for a week Sunday, afraid that some other crazy thing will happen to my body while I'm away from home.  DH says he'd be fine with staying home, and he would because he's a sweetie, but he SO loves the week at the beach and he's been working so hard.  Can't make up  my  mind. 

    I have been using baby shampoo (not J&J, but a Kroger brand that doesn't smell nearly as good) and today my head feels better.  Now as soon as I typed that, a couple of places are itching again. 

  • MoinTexas
    MoinTexas Member Posts: 13
    edited July 2008

     Hi, I'm back after only posting once, just before I started my 4-cyle tx on 6/19.  I'm now day 16 on first cycle. 

    catlover, I had hives last week.  Not very many, but at least one on each leg and arm but none on torso, 2 on face.  One on back of left arm (non surgery arm) was about 7 inches by 4 inches - whole back of the arm and puffed up a lot.  happened in middle of night, so called chemo nurse next day.  She said take benadryl and put cortisone cream on.  I took 3 benadryl doses (1 every 12 hours) and the cream, and they faded within a week to just little red dots.  Have to resist the urge to scratch them or they stay longer!

    I was so happy to find that I wasn't having too many se's.  I had some  mild nausea on day 4 but lay down, didn't take anything, and was able to eat by evening.  Didn't come back but stomach and body generally was very shaky for at least 6 or 7 days.  Haven't had any other side effects except the obvious Dex ones that go away.  I was so pleased when I went to the Dr.  yesterday for my 14 day blood test - had no fatigue or bleeding - I was just sure I was fine..... haha    My red blood count and  platelets were fine; however, my WBC and particularly the neutrofils were rock bottom.   My absolute neutrofil count was 346 - and I had read where at 500 they will put us in the hospital with IV antibiotics to guard against infections... SO, taught how to give myself Neupogen shot, sent home with 7 more for isolation until it goes up, plus antibiotics.  Have some spasm-type back pain but not too bad.  Doesn't hurt at all when I stand up-wonder if I can learn to sleep that way.  Hope the count is back up by 7/10 for my 2d tx; don't want to put it off.  And I was so pleased it was going so welll,...so disappointed as I wanted to go actually have dinner out and a movie this weekend!   But I feel lucky I haven't had the other things.  So far my temperature is normal.  Hope everybody else is able to get out this 4th of July--my sister in law is with me and I'm sure she is feeling like she is in jail!!  

    Best holiday wishes!  Marilyn 

  • terridwo
    terridwo Member Posts: 31
    edited July 2008

    Hi All,

    Just found this board yesterday.  I haven't posted since my surgery, but go on quite often to read posts.  It has been extremely helpful.  I started my first of 4 TC last Friday.  Got through it ok with the ususal regimen that most seem to follow and the usual se's.  On day 6, though I started feeling lousy again, worse, headache, sore throat, etc.  Catlover, I wanted you to know that I was supposed to call if my temp. got to 100.5.  I ended up calling anyway when I kept feeling worse and  the fever was fluctuating between 99 and 100.  My onc had me come in for blood work and my WBC was way low and she put me on Leviquin, a strong anti-biotic you only take once a day.  I felt better this a.m, but fever returned about an hour ago, along with headache.  She told me if I hadn't come in, I probably would have ended up in there over the weekend for IV antibiotics.  So I don't know what your doc said, but I wouldn't wait long if the fever persists.

    Thanks to all of you for sharing your thoughts, it's so reassuring to hear that someone is feeling the same things and that this is all "normal".  Does anyone else have an expander.  I had uni-mast with expander on May 2.  Since, the chemo, the pain where the expander is and under my armpit (1 node removed/neg) are as bad as a month ago.  I was wondering if anyone else is experiencing this.  I'm back to taking percoset which I pretty much had not needed at all before tx.  I also have pain in the center of my chest which is supposedly from the Neulasta.

    Happy Fourth All,

    Terri

  • otter
    otter Member Posts: 757
    edited July 2008

    Terri, I also had pain and swelling at my mast/SNB incision, chest wall, and under my arm, after each TC treatment.  I'm now 4-1/2 wks past my last tx, and my arm and chest on the mast/SNB side are as stiff as they were 2 wks after my surgery (which was in Feb. '08).  I am back to doing the stretching exercises I did right after my surgery, because if I didn't, I am sure my range-of-motion would be pretty bad again.  I think quite a few of us have had that problem during our TC treatments.

    otter

  • Genieruth
    Genieruth Member Posts: 6
    edited July 2008

    I met with my onc last week about the decision to have tx 4 of TC. After the bad experience after tx 3, I am very nervous about going ahead with tx 4. My onc still feels that I had a blood infection even though all the cultures came back negative. She says she has never seen the kind of reaction(severe rigors & fever) that I had except with an infection. Anyway, I have decided to go ahead with tx 4 on July 9 - they will watch me very carefully and have me stay for a couple of hours after tx for observation. I was on Levaquin in the hospital and for a week at home - as a result now I have had to be on Flagyl for 7 days. I'm beginning to wonder if my system will ever get back to normal. Like slortiz, I've not had many antibiotics during my 67 years and have felt healthier because of it.

    Anyway, please keep me in your thoughts and pray that tx 4 will be easier than tx 3.

    God bless,

    GenieRuth

    DX 3/11/08,Triple negative, KCI 99%, stage 1, grade 3, 0/1 nodes

  • terridwo
    terridwo Member Posts: 31
    edited July 2008

    otter, thanks for the 1-up about the pain and stiffness.  It's not encouraging, but at least I know it's nothing I'm doing wrong.  This is one of the se's I didn't hear about, along with nail problems and hives. 

    GenieRuth, best of luck to you on tx 4

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Marilyn & Terri, did either of you have a Neulasta shot after your tx's?  I'm wondering because I did, but still wound up with the sudden fever yesterday.  They called me in Levaquin (must be the darling anti-bio of the moment) and a steroid pack for the hives, so things are looking up.  BUT, we are supposed to go to the beach tomorrow for 7 days and I DON'T KNOW WHAT TO DO.  I thought the Neulasta kept our counts up reasonably well, but I'm at day 10, the beginning of a 7 day nadir, which seems like the stupidest time to go on vacation.  I can be really careful, but eating out seems like it could pose a problem....?  We had been out to eat the night before the fever.  I don't want to make my hubby lose his week at the beach, and I'd enjoy it too, but at what cost???  I have to make a decision soon so I can call the inn if we aren't coming.  Anyone have any words of wisdom about vacationing while in this pickle???   Thanks (I'm needy today)!

  • terridwo
    terridwo Member Posts: 31
    edited July 2008

    Catlover, yes I had the Neulasta shot the morning after tx.  This a.m had no fever, took my 3rd Levaquin and now 1:00 p.m. and my temp is 100.3.  Getting frustrated.  I really don't know what to say about vacation, I think I would go.  At least you are on the antibiotics and I heard it's powerful.  (though surprised I'm still running a temp today).  I don't know how you felt, but I do feel better today.  I thought after the first five days we were pretty worry free till the next tx!!!  From all I've read on these posts it sounds like everyone is different and each tx can turn up different se's.  Sounds like a crapshoot to me.  I'm sure someone further along can give you better advice.  If you do go, I hope you have a great time.  I'm supposed to go to a family picnic in 1/2 hour.  Not sure what to do either, but that is a lot different than going away for a week.  Good Luck and feel better!!!

  • terridwo
    terridwo Member Posts: 31
    edited July 2008

    Catlover, yes I had the Neulasta shot the morning after tx.  This a.m had no fever, took my 3rd Levaquin and now 1:00 p.m. and my temp is 100.3.  Getting frustrated.  I really don't know what to say about vacation, I think I would go.  At least you are on the antibiotics and I heard it's powerful.  (though surprised I'm still running a temp today).  I don't know how you felt, but I do feel better today.  I thought after the first five days we were pretty worry free till the next tx!!!  From all I've read on these posts it sounds like everyone is different and each tx can turn up different se's.  Sounds like a crapshoot to me.  I'm sure someone further along can give you better advice.  If you do go, I hope you have a great time.  I'm supposed to go to a family picnic in 1/2 hour.  Not sure what to do either, but that is a lot different than going away for a week.  Good Luck and feel better!!!

  • MsKarin
    MsKarin Member Posts: 105
    edited July 2008

    This Nadir thing has had me confused. Is the nadir time frame figured out without receiving neulasta? I'm thinking it is. I had my CBC on day 9 of my 1st treatment and day 12 of my second. Both times my counts had already ready returned to normal.

    Enjoy the day, Karin

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Karin, my onc based her estimation of the nadir on the drugs we're taking.  I think they consider it the same whether you have Neulasta or not, from what I gathered.  I don't get my counts checked in between treatments, so I have no idea where I am!  After yesterday's fever, I suspect somewhat low....  I'm hoping the Neulasta will kick back in with me like it apparently has with you!

    Terri (my name is Terri too, BTW!), I hope your fever leaves you alone today and stays gone.  I can imagine how frustrating it is to be taking the a/b and still having it.  If you're feeling better, it's probably on it's last hurrah.  I haven't checked my temp today, but I don't have the chills I was having yesterday so hopefully it's OK.  Your phrase "crapshoot" is exactly what my onc called the whole thing, so I guess you are using medical terminology!  I think I'm going to give the beach a try...we go to a very small town so there aren't the big family crowds all over the place like some over-visited beaches.  I figure I'll stay away from salads in restaurants, eat just cooked food (I don't eat meat, so that's not a threat), and wash my hands in like I'm OCD all week.  Again, a crapshoot!!

  • otter
    otter Member Posts: 757
    edited July 2008

    Hey, all--

    I'm pretty sure the wbc nadir occurs at about the same time with or without Neulasta.  It just lasts longer and goes deeper without the Neulasta "support".

    Each of us has had our own set of SE's, and each cycle seems to be a bit different; but there are some common themes.  I was told my neutrophil nadir would occur between days 10 and 14 (even with Neulasta), so I should be careful around crowds on those days.  I thought that was a bit late, but it was exactly when I developed a fever during my 3rd and 4th rounds of TC.  There may have been a low wbc point around day 7, too.  That's the nadir for Taxotere, according to the papers I read.  I did run a low-grade fever (100.0 or less) around day 6 or 7 of my 1st and 2nd cycles, but it never got any worse.

    Catlover, the problem isn't the vacation--it's the people.  If you can keep yourself somewhat "isolated" (think quarantine), it shouldn't matter where you are.  Even a beach is probably OK, as long as you aren't hanging around the party crowd a lot.  Shaking hands, sharing drinks, eating communal meals around a crowded table, hugging small children--those are the types of things I would worry about.  Oh, and if you do go, be sure you can get in touch with your onco if necessary; and scout around for a late-night pharmacy and a walk-in clinic.  And, be sure to not get too much sun--sun exposure and Taxotere do not go well together!

    Terriwdo, I was placed on antibiotics for a week during each of my last two treatments--Avelox for tx #3 and Levaquin for #4--because I developed a temp > 100.4.  My temp went back down right away during tx #3, but during tx #4 it continued to be around 100.4 or 100.5 in the afternoons and evenings some days, even while I was on the antibiotic.

    I called my onco's office a couple of times about the continuing fever, but she kept reassuring me that it would be OK.  She also encouraged me to go ahead and take Advil, because that's what I would ordinarily take to suppress aches and pains and a low-grade fever.  She said my fever was actually pretty low, my wbc should be back to normal shortly (if it wasn't already), I was on an appropriate antibiotic, and I wasn't getting any worse.  She was right--after 7 days on Levaquin, my temp was back to normal and I was feeling fine.  I guess all that medical experience counts for something after all!  A disclaimer:  be sure to call your onco if you have any concerns.  That's why we pay them all that money.

    I need to go eat lunch--somehow that got skipped.  I was rescuing some spider lily bulbs an overly enthusiastic armadillo dug up last night, and the time got away from me.  Now I have a bucket full of bulbs I have to replant.  (Old-fashioned spider lilies bloom in the fall and are dormant in spring and summer.)

    otter

  • catlover44
    catlover44 Member Posts: 78
    edited July 2008

    Thanks, Otter for the advice.  I'm still annoyingly on the fence about going.  It's just the DH and me, and a very uncrowded beach and a quiet, laid-back inn.  But it seems suddenly that germs are lurking everywhere that I normally wouldn't even have to think about.  DH has been very stressed work-wise for the past couple of weeks and needs a break, but I can't decide if he'd be more keyed up worrying about me catching something on vacation, or just staying home.  I'm thinking I'll be such a pain if we go that it won't be much fun....can't hang out at our favorite restaurants, can't drink "adult" drinks, etc.  I need divine guidance for such a simple thing!  Hope your spider lilies recover from the abrupt digging!