AIMSS: How Aromatase Inhibitors Can Affect Hands and Wrists
AIMSS: How Aromatase Inhibitors Can Affect Hands and Wrists
January 13, 2026
If you’re taking an aromatase inhibitor, you may have pain in your hands and wrists. Dr. David Bozentka explains the syndrome.
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Bone and joint pain are some of the most common side effects of aromatase inhibitors, medicines for hormone receptor-positive breast cancer. The official name for this is aromatase inhibitor associated — or sometimes induced — musculoskeletal syndrome, also called AIMSS. Many people report pain in the knees, ankles, and hips while taking an aromatase inhibitor, but the hands and the wrists also might be affected.
Hand expert Dr. David Bozentka discusses how AIMSS can affect the wrists and hands, including symptoms such as carpal tunnel syndrome, trigger finger, and tendonitis.
Listen to the episode to hear Dr. Bozentka explain:
- the theories why aromatase inhibitors cause joint and bone pain, or AIMSS
- how to decrease the risk of AIMSS
- how carpal tunnel syndrome, trigger finger, and tendonitis are treated