Capivasertib and fulvestrant injection

I am starting this as second line as well, on Wednesday. I came to get insights, but it appears that there are so many mentions of one of the drugs but not both. Perhaps we need to take a little dive into these as well. Hoping things go well for us both 💪👍

Hi. I started as planned as well. So 4 days done and I have not experienced anything out of the ordinary. Maybe a little more tender buttocks, but that lasted maybe two days. The injections went well, without any prep on my part. But, I had made myself so nervous reading about it I think my anxiety got the worst of me and I almost fainted during the first injection. The nurse was so kind, and she got a chair under me in time to avoid catastrophe. What a whimp 😊 After all the needles and biopsies and indignities we go through, who knew this would bring me down. Anyway, all good. She got the full injection in, and I got my second one while reclining on my side. On my drive home I did put on my car heater as well as the seats. And I took my exercise class in the evening because I read one should keep active, and had no issues.
in terms of the Capivasertib, I went through my first four days and things seem fine 🤞Not sure about you, but my MO prescribed me Claritin and I take it every morning with the Capivasertib. Maybe that is the ticket to avoiding some of the rash and itchiness. I don’t know, but I haven’t needed to take any of the other drugs associated with the other side effects. Oh, and I’ve seen a dietician at diabetes clinic and she showed me how to take my blood glucose levels. So, it seems that my doc has everything taken care of, and I hope I continue to tolerate things. Obviously I want to see a reduction in my liver met ( ultrasound in July will show that) but I think that is likely given the research. It is just if the body allows the drugs to do their job.
I hope your treatments proceeds without I’ll effect as well. 🤞please continue to update, as will I.
Happy Mother’s Day if it applies. Not to me, so heading out now to take my 95 year old Mom out to breakfast. 🌻🪻

Hi all,

I had my first injections on 5/15. I used ice packs and put lidocaine cream on prior to injections (very messy, even with trying to cover with plastic wrap! I plan on buying and trying the over-the-counter patches). I felt the one injection more then the other… the nurse said it was likely bc that side had a chance to warm up from my sitting on the ice pack? Anyway, ironically, the side that didn't hurt still sometimes feels like there is a knot of pain at the injection site. I was told to massage the locations to work out the knots; I have rubbed them some.

I experienced nausea within the first couple of days, mainly after getting out of a moving car. The anti-nausea melts have helped with that. My major "ugh" is the bone pain! It isn't always there/noticeable. But when it shows up, it is very painful! One night, about one week after the injections, the pain was so bad I couldn't sleep! I had to take 3 ibuprofen, compared to the occasional 1 I usually take to ward off pain.

I am hoping the bone pain improves as my body gets used to the medication. I will be adding the Capivasertib sometime in early July, after 3 cycles of the Fulvestrant.